FDG PET/CT in IgG4-related Disease Involving the Urethra.

Clin Nucl MedOct 20, 2026 (epub)
Case ReportNuclear MedicineRadiology (Diagnostic)UrologyRheumatology

Xiaojun Man, Changming Dong, Aisheng Dong et al.

✦ AI-curated · Sources linked

Case in brief

A woman with IgG4-related disease presented with obstructive urinary symptoms. FDG PET/CT and delayed pelvic PET/MRI demonstrated marked circumferential urethral wall thickening with intense diffuse FDG uptake (SUV max 13), alongside hypermetabolic lymph nodes in pelvic, retroperitoneal, mediastinal, pulmonary hilar, and axillary regions. The report identifies the urethral abnormality as IgG4-related disease; the abstract does not describe its subsequent resolution.

What made this case unusual

The case highlights urethral involvement by IgG4-related disease, an uncommon site, with circumferential thickening and intense diffuse FDG uptake on imaging.

Diagnostic / clinical pearl

Include IgG4-related disease in the differential diagnosis of FDG-avid urethral or periurethral lesions, particularly when imaging also shows lymphadenopathy at multiple sites.

Source

PubMed · PMID 42912667

Published in Clin Nucl Med. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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