Secondary Syphilis.

Med J AustOct 29, 2026
Case ReportInfectious DiseasesOphthalmologyDermatology

Fiona Spencer, Michael Taggart

✦ AI-curated · Sources linked

Case in brief

A 46-year-old man presented with two months of progressive, painful visual loss. Examination showed bilateral panuveitis alongside widespread ulcerative skin lesions and alopecia. Treponemal antibody testing was positive, and the rapid plasma reagin titre was 1:2048. Together, these findings were consistent with severe secondary syphilis in an otherwise immunocompetent patient. The abstract does not report treatment or clinical resolution.

What made this case unusual

Severe secondary syphilis presented with bilateral panuveitis and progressive painful visual loss in an otherwise immunocompetent patient.

Diagnostic / clinical pearl

In a patient with panuveitis and compatible skin or hair findings, include syphilis in the diagnostic assessment and interpret serology alongside the clinical presentation.

Source

PubMed · PMID 42947270

Published in Med J Aust. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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AI-generated summaries may contain errors or omissions. Verify clinically important information with the original publication.

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