Prevalence of Sleep Disorders in Patients With Knee, Hip, and Hand Osteoarthritis: A Systematic Review With Meta-Analysis.
Katrine Kindtler Krag-Andersen, Josephine Hauge van Zaane, Giovanna Laura Neves Antonio Gaban et al.
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In 30 seconds
This prevalence systematic review and meta-analysis assessed insomnia, obstructive sleep apnea, restless legs syndrome, and narcolepsy in people with knee, hip, or hand osteoarthritis. It included 18 observational and interventional studies involving 202 847 participants. Pooled prevalence was highest for insomnia at 42% (95% confidence interval [CI]: 34% to 51%), followed by sleep apnea at 37% (95% CI: 6% to 67%) and restless legs syndrome at 35% (95% CI: 10% to 61%). No studies reported narcolepsy. Estimates varied across studies, and certainty of evidence was very low.
Key findings
- Pooled insomnia prevalence was 42% (95% confidence interval [CI]: 34% to 51%).
- Sleep apnea prevalence was 37% (95% CI: 6% to 67%), and restless legs syndrome prevalence was 35% (95% CI: 10% to 61%).
- No included studies reported narcolepsy; prevalence estimates varied with diagnostic criteria and sample characteristics.
Why it matters
Sleep disorders were common in the reviewed osteoarthritis populations, particularly insomnia. Awareness of this overlap may help clinicians consider sleep symptoms when assessing people with knee, hip, or hand osteoarthritis. However, the wide variation in estimates and very low certainty of evidence mean that the pooled figures should be interpreted cautiously.
What to keep in mind
The review found large between-study heterogeneity, few high-quality studies, and very low certainty of evidence; no studies reported narcolepsy.