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1998 articles
October 202624
Short-term Rhodiola rosea supplementation improves premenstrual symptoms, reaction time, and perceived exertion in female taekwondo athletes: a randomised double-blind placebo-controlled trial.
This randomised, double-blind, placebo-controlled trial tested 10 days of Rhodiola rosea (RR) supplementation during the estimated symptomatic premenstrual phase in 24 female taekwondo athletes with moderate-to-severe…
Safety and immunogenicity of a first-generation modified vaccinia virus Ankara-vectored SARS-CoV-2 vaccine candidate with mRNA-based booster vaccination: A phase 1 trial.
This phase 1 trial assessed safety and immune responses to the MVA-vectored SARS-CoV-2 vaccine MVA-SARS-2-S in 30 healthy, SARS-CoV-2-naive adults given two doses 28 days apart, with six-month follow-up.
TRANSFORM-1 phase 3 study: efficacy and safety of navitoclax plus ruxolitinib in patients with untreated myelofibrosis.
TRANSFORM-1 was a multicentre, randomised phase 3 trial comparing navitoclax plus ruxolitinib with placebo plus ruxolitinib in Janus kinase inhibitor-naïve adults with intermediate-2 or high-risk myelofibrosis.
Coronary microvascular dysfunction in patients undergoing transcatheter aortic valve implantation: A systematic review and meta-analysis.
This systematic review and meta-analysis examined coronary microvascular dysfunction (CMD) in adults with severe aortic stenosis undergoing transcatheter aortic valve implantation (TAVI).
The Moderating Effects of Race and Ethnicity on a Motivational Interviewing Intervention for Improving Physical Health Among Patients With Peripheral Artery Disease: Secondary Analysis of a Pilot Randomized Trial.
This secondary analysis of a pilot randomized trial examined whether social determinants of health modified motivational interviewing (MI) effects on walking distance and weight among community-dwelling adults with…
Quality of recovery after arthroscopic meniscectomy with remimazolam or propofol anesthesia: A randomized controlled trial.
This randomized controlled trial compared propofol-based with remimazolam-based total intravenous anesthesia in adults undergoing elective arthroscopic meniscectomy.
A Phase II Multicenter Trial of Rucaparib and Nivolumab as Maintenance Therapy in Patients with Advanced Biliary Tract Cancer: BilT-02.
BilT-02 was a multicenter phase II trial of rucaparib plus nivolumab as maintenance therapy for patients with advanced biliary tract cancer whose disease had not progressed after 4 to 6 months of first-line…
Acceptability and Feasibility of an Islamic Faith-Based Smoking Cessation Intervention Delivered via WhatsApp for Muslim Smokers in Saudi Arabia: Pilot Randomized Controlled Trial.
This two-arm pilot randomized controlled trial assessed the feasibility, acceptability, and preliminary outcomes of a 21-day Islamic faith-based smoking cessation intervention delivered by WhatsApp to adult Muslim…
Comparative Efficacy and Safety of Systemic Immunomodulatory Therapies for Non-Infectious Uveitis: A Systematic Review With Pairwise and Network Meta-Analyses.
This systematic review and network meta-analysis compared systemic immunomodulatory therapies for non-infectious uveitis (NIU), including evidence from seven studies with 992 participants: six randomised trials and one…
Blood-based biomarkers in patients with recurrent, persistent, or metastatic endometrial cancer treated with olaparib and cediranib: Results from NRG-GY012.
This biomarker analysis of the phase 2 NRG-GY012 clinical trial assessed blood-based markers and outcomes among patients with recurrent, persistent, or metastatic endometrial cancer treated with olaparib, cediranib, or…
Bacterial infections and antibiotic susceptibility in children with sickle-cell anemia on malaria chemoprevention using Dihydroartemisinin-piperaquine (DP) or Sulfadoxine-pyrimethamine (SP) in Uganda.
This analysis nested within a randomized, double-blind trial assessed bacterial infections and antimicrobial resistance among Ugandan children aged 6 months to 15 years with sickle-cell anemia receiving weekly…
Efficacy of Stromal Vascular Fraction for Scar Prevention: A Multicenter, Double-Blinded, Randomized Controlled Trial.
This multicenter, double-blinded, placebo-controlled randomized trial evaluated intraoperative stromal vascular fraction (SVF) injections for scar prevention in 45 patients undergoing free tissue transfer at three…
Giant Cystic Lymphangioma of the Transverse Mesocolon in a 7-Year-Old Child: A Case Report.
A 7-year-old girl presented with several weeks of vomiting, abdominal pain and progressive distension. Examination found a large abdominal mass; laboratory results were unremarkable.
Inside a Programmer's Brain: Dissociating Code and Language Comprehension Networks Using a Novel fMRI-ESM Protocol.
A professional software engineer with an IDH-mutant astrocytoma in the left middle frontal gyrus underwent preoperative fMRI and intraoperative electrical stimulation mapping (ESM) to assess both language and code…
Artificial intelligence EEG biomarkers for schizophrenia diagnosis: Systematic review with PROBAST+AI assessment.
This systematic review assessed the diagnostic performance and methodological quality of AI models using resting-state EEG to identify schizophrenia or first-episode psychosis.
The impact of prophylactic azithromycin on the developing preterm gut microbiome and resistome.
This multicentre, double-blind, randomised, placebo-controlled trial examined the effects of 10 days of prophylactic intravenous azithromycin on the gut microbiome and resistome of 693 preterm infants born before 30…
Modulation of the gut microbiome and resistome by antibiotic use, but not by subsequent 2'-fucosyllactose intake, in adults with overweight or obesity.
This randomized, double-blind, placebo-controlled intervention examined gut microbiome and resistome changes in 18 adults with overweight or obesity after seven days of vancomycin, followed by eight weeks of…
Long-Acting HIV Therapy in African Adults with Adherence Challenges.
This phase 3b, open-label, randomized trial compared long-acting injectable cabotegravir plus rilpivirine with daily oral dolutegravir-based therapy in adults in Kenya, South Africa, and Uganda who had suppressed HIV-1…
Intracranial metastasis as a mimic of amyloid-related imaging abnormalities.
A 79-year-old woman with biomarker-confirmed Alzheimer’s disease developed progressive vasogenic edema while receiving lecanemab.
The ability of the commercial inertial measurement unit-based gait system in determining Parkinson's disease: A systematic review with meta-analysis of cross-sectional studies.
This systematic review and meta-analysis of cross-sectional studies assessed whether commercial inertial measurement unit (IMU)-based gait systems distinguish people with Parkinson’s disease (PD) from healthy controls.
Key Predictors of Cerebral Vasospasm Following Subarachnoid Hemorrhage: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis examined observational evidence on factors associated with cerebral vasospasm after subarachnoid hemorrhage (SAH).
Multimodal assessment of exceptional responders refines subtyping-directed precision treatment in HR+/HER2- breast cancer.
This clinical-trial analysis examined whether multimodal tumour and clinical features could clarify exceptional responses to subtype-directed treatment in locally advanced HR+/HER2− breast cancer.
Efficacy and Safety of Necitumumab and Pembrolizumab Combination Therapy in Advanced Non-Small Cell Lung Cancer with ≥50% PD-L1 Expression: A Nonrandomized Phase II Trial.
This nonrandomized, multicenter, open-label, single-arm phase II trial evaluated first-line pembrolizumab plus necitumumab in 50 patients with previously untreated advanced NSCLC and PD-L1 tumor proportion score ≥50%.
Evidence on Glutathione and Boosters for Prevention of Chemotherapy-Induced Neuropathy: A Systematic Review and Network Meta-Analysis.
This systematic review and network meta-analysis compared glutathione (GSH) and GSH boosters for preventing chemotherapy-induced peripheral neuropathy (CIPN), drawing on 25 randomised controlled trials involving 1625…
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