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1998 articles

October 202624

Case ReportCardiothoracic Surgery

Endoscopic secondary chordae transfer and edge-to-edge repair for the treatment of asymmetric anterior leaflet prolapse.

A 59-year-old patient with Barlow’s disease presented with severe mitral regurgitation from asymmetric anterior leaflet prolapse.

Multimed Man Cardiothorac SurgOct 14, 2026Read case
Clinical ResearchCardiologyOpen access

Ramadan Fasting in Chronic Heart Failure: A Systematic Review.

This systematic review assessed clinical studies of Ramadan fasting in people with chronic heart failure. Searches of PubMed, Scopus, and Web of Science identified seven eligible studies from 137 records; most were…

Curr Cardiol RepOct 14, 2026Read summary
Clinical ResearchOrthopedic Surgery

Antibiotic-Loaded Hydrogel, Calcium Bead, and Cement in Periprosthetic Joint Infection Following Hip-Knee Arthroplasty: A Systematic Review and Meta-Analysis of Commercially Available Products.

This systematic review and meta-analysis compared defensive antibacterial coating (DAC), calcium sulfate beads, and antibiotic-loaded bone cement for preventing or managing periprosthetic joint infection after total hip…

J Am Acad Orthop Surg Glob Res RevOct 14, 2026Read summary
Clinical ResearchAnesthesiologyOpen access

Effect of a Subanesthetic Dose of Esketamine on Postoperative Sleep Disturbance After Oocyte Retrieval Under Intravenous Anesthesia: A Randomized Controlled Trial.

This randomized, double-blind, placebo-controlled trial assessed whether intravenous esketamine reduces postoperative sleep disturbance (PSD) in women undergoing oocyte retrieval with intravenous anesthesia.

Drug Des Devel TherOct 14, 2026Read summary
Clinical ResearchOncology (Medical)

Dietary and lifestyle quality and endometrial cancer: Incidence and survivorship outcomes-An umbrella review of systematic reviews and meta-analyses.

This umbrella review of 21 systematic reviews, including meta-analyses, assessed composite diet and lifestyle quality in relation to endometrial cancer (EC) risk and survivorship outcomes.

PLoS OneOct 14, 2026Read summary
Case ReportNeurosurgery

Painless Spontaneous Spinal Epidural Hematoma Mimicking Acute Ischemic Stroke: A Case Report.

A woman in her early 60s receiving anticoagulant and antiplatelet therapy developed neck tightness and numbness in both limbs without pain, followed by transient right hemiplegia and rapid neurological deterioration.

Ann Ital ChirOct 14, 2026Read case
Case ReportMedical GeneticsOpen access

Severe growth retardation in Dent disease: a case report of a novel OCRL variant.

A 12-year-old boy with marked short stature and poor weight gain had low-molecular-weight proteinuria, haematuria, hypercalciuria and bilateral nephrocalcinosis, with normal renal function and no relevant family…

CEN Case RepOct 14, 2026Read case
Case ReportCardiology

Integrated Use of Extracorporeal Membrane Oxygenation and Molecular Adsorbent Recirculating System for Refractory Cardiotoxic Ingestion: A Single-Center Case Series.

Five consecutive patients with severe calcium-channel blocker or beta-adrenergic antagonist ingestions developed profound hypotension and respiratory failure despite standard therapies.

Crit Care ExplorOct 14, 2026Read case
Clinical ResearchOncology (Medical)Open access

Volumetric discordance between ¹⁸F-FET-PET/MRI and MRI-based radiotherapy target volumes in high-grade glioma: a prospective pilot study (FETSMaRT).

This prospective pilot study enrolled 30 patients with WHO grade 3 or 4 high-grade glioma receiving postoperative radiotherapy.

J NeurooncolOct 14, 2026Read summary
Clinical ResearchPreventive Medicine / Public Health

A Single Exercise Session Elicits a Transient Kynurenine Metabolic Signature in Health and Disease: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis examined acute changes in circulating tryptophan (TRP) and kynurenine-pathway metabolites after a single exercise session.

FASEB JOct 14, 2026Read summary
Clinical ResearchGeneral SurgeryOpen access

Routine versus postoperative CRP/CT guided selective diverting ileostomy after laparoscopic low anterior resection for rectal cancer: a comparative randomized controlled trial.

This randomized controlled trial compared postoperative CRP/CT-guided selective diversion with routine diverting ileostomy in 200 patients with stage II or III middle or lower rectal cancer undergoing laparoscopic low…

BMC SurgOct 14, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Characterizing vaginal misoprostol induction in individuals with and without severe obesity.

This secondary analysis of the vaginal misoprostol arm of a cluster-randomized trial compared term inductions in individuals with BMI < 40 versus ≥ 40 kg/m².

J Matern Fetal Neonatal MedOct 14, 2026Read summary
Clinical ResearchDermatology

Fecal microbiota transplantation for the treatment of neurogenic rosacea: protocol of a randomized, blinded, placebo-controlled explorer study.

This publication describes the protocol for a single-center, randomized, double-blind, placebo-controlled exploratory trial of fecal microbiota transplantation (FMT) in patients with neurogenic rosacea, a phenotype…

Ann MedOct 14, 2026Read summary
Clinical ResearchPlastic Surgery

Multiple-Staged Versus Single-Stage Surgical Excision for the Reconstruction of Congenital Melanocytic Nevi: A Meta-Analysis of Efficacy and Safety.

This meta-analysis compared multiple-staged with single-stage excision and reconstruction for congenital melanocytic nevi (CMN). It pooled seven retrospective cohort or clinical controlled studies involving 578 patients.

Ann Ital ChirOct 14, 2026Read summary
Clinical ResearchAnesthesiology

Pericapsular Nerve Group Block Versus Femoral Nerve Block for Analgesia in Newly Admitted Patients With Hip Fractures: A Randomized Controlled Trial.

This randomized controlled trial compared preoperative pericapsular nerve group (PENG) block with femoral nerve block (FNB) in 60 newly admitted patients with hip fractures.

Clin J PainOct 14, 2026Read summary
Clinical ResearchGeriatrics

Vegetarian and Vegan Diets and the Risk of Hip Fracture in Adults: A Systematic Review and Meta-analysis.

This systematic review and meta-analysis assessed hip-fracture risk in adults following vegetarian or vegan diets compared with meat-eaters. Four cohort studies involving 529 672 participants were included.

Nutr RevOct 14, 2026Read summary
Clinical ResearchOncology (Medical)

Impact of body composition on clinical outcomes in patients with hepatocellular carcinoma: A systematic review and meta-analysis.

This systematic review and meta-analysis examined associations between body composition and outcomes in patients with hepatocellular carcinoma (HCC), across curative, locoregional, systemic, and mixed treatment…

Hepatol CommunOct 14, 2026Read summary
Case ReportMedical Genetics

Aberrant splicing caused by a homozygous AK2 c.498 + 1G > A variant in a patient with reticular dysgenesis and concurrent B-cell acute lymphoblastic leukemia.

A boy with reticular dysgenesis (RD), a severe immunodeficiency associated with biallelic AK2 loss of function, was also diagnosed with B-cell acute lymphoblastic leukemia (B-ALL).

GeneOct 14, 2026Read case
Clinical ResearchPhysical Medicine & RehabilitationOpen access

Clinical outcomes of low versus high intensity laser therapy in patients with subacute carpal tunnel syndrome: A randomized, single-blinded, controlled trial.

This single-blinded randomized controlled trial compared high-intensity laser therapy (HILT), low-level laser therapy (LLLT), and sham laser, each alongside physiotherapy, in 69 people with electromyography- and…

Lasers Med SciOct 14, 2026Read summary
Clinical ResearchDermatology

The Use of Cannabidiol in Cutaneous Wound Healing: A Systematic Review.

This qualitative systematic review assessed cannabidiol (CBD) for cutaneous wound healing, including in vivo studies and clinical trials identified through searches of seven databases. Six studies were included.

FASEB JOct 14, 2026Read summary
Clinical ResearchDermatologyOpen access

Targeting an IL-17/IL-36 pathogenic hub in hidradenitis suppurativa with a bispecific antibody.

This phase I/II proof-of-concept clinical trial evaluated HB0043, a bispecific antibody targeting IL-17A and IL-36R, in patients with severe, tunnel-dominant Hurley Stage III hidradenitis suppurativa.

Signal Transduct Target TherOct 14, 2026Read summary
Case ReportPhysical Medicine & RehabilitationOpen access

Surgery to treat autonomic dysreflexia due to cubital tunnel syndrome in cervical spinal cord injury: a case report.

A 74-year-old woman with remote C6 spinal cord injury (AIS B) developed recurrent autonomic dysreflexia episodes that had not responded to standard measures.

Spinal Cord Ser CasesOct 14, 2026Read case
Clinical ResearchPsychiatry

An Internet-Based Cognitive-Behavioral Program, With Telephone Support, Improves Pain, Disability and Emotional Well-Being in Adults With Chronic Pain: Randomized Controlled Trial of the Pain Course With 2-Year Follow-Up.

This randomised controlled trial evaluated an internet-delivered, cognitive-behavioral Pain Course with clinician support in adults with chronic pain living in Ireland.

Clin J PainOct 14, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Camrelizumab plus chemotherapy as induction therapy followed by concurrent chemoradiotherapy and camrelizumab consolidation in limited-stage small cell lung cancer: a randomized phase II trial.

This randomized phase II trial compared a camrelizumab-based induction and consolidation strategy with induction chemotherapy followed by concurrent chemoradiotherapy (CRT) alone in previously untreated patients with…

Signal Transduct Target TherOct 14, 2026Read summary

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