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1998 articles

October 202624

Clinical ResearchObstetrics & Gynecology

The Impact of Telemedicine Interventions on Maternal and Fetal Outcomes in Women With Gestational Diabetes: Systematic Review and Meta-Analysis of Randomized Controlled Trials.

This systematic review and meta-analysis pooled 23 randomized controlled trials involving 3055 women with gestational diabetes to assess telemedicine and maternal and fetal outcomes.

J Med Internet ResOct 23, 2026Read summary
Clinical ResearchGastroenterology

Gut virome remodeling after fecal microbiota transplantation is associated with virus-bacteria co-variation and metabolic response in obesity and type 2 diabetes.

This randomized controlled trial examined longitudinal fecal virome and bacteriome changes after fecal microbiota transplantation (FMT) in people with obesity and type 2 diabetes.

Gut MicrobesOct 23, 2026Read summary
Case ReportInfectious Diseases

Streptococcus constellatus-Associated Lemierre Syndrome Presenting With Cavitating Septic Pulmonary Emboli Managed by Video-Assisted Thoracoscopy.

A previously healthy 25-year-old man presented with a week of dyspnea, productive cough, fever, and hemoptysis, with severe hypoxemia and respiratory distress.

Am J Case RepOct 23, 2026Read case
Clinical ResearchRadiology (Diagnostic)

The entorhinal cortex atrophy score for diagnostic distinction between phases of the Alzheimer's disease continuum.

This systematic review assessed the Entorhinal Cortex Atrophy (ERICA) visual score for distinguishing subjective cognitive decline (SCD), mild cognitive impairment (MCI), and Alzheimer’s disease (AD) dementia.

Arq NeuropsiquiatrOct 23, 2026Read summary
Case ReportOncology (Medical)Open access

Successful treatment with BrECADD in a patient with Dubin-Johnson syndrome and classic Hodgkin lymphoma: a case report.

A 26-year-old man with advanced-stage classic Hodgkin lymphoma also had Dubin–Johnson syndrome (DJS) associated with a homozygous ABCC2 variant, c.2291G>A (p.Gly764Asp).

Cancer Chemother PharmacolOct 23, 2026Read case
Clinical ResearchDermatology

Balancing safety and efficacy in photodynamic therapy for facial port-wine stains in children aged 2-7 years: a prospective controlled study of light-intensity optimization.

This open-label, prospective controlled study compared two light intensities for hemoporfin-mediated photodynamic therapy in children aged 2–7 years with facial port-wine stains.

J Dermatolog TreatOct 23, 2026Read summary
Case ReportUrology

Perineal Urethrostomy After Urethral Stricture: Step-by-Step Surgical Technique.

A 73-year-old man with complex, recurrent urethral stricture after multiple reconstructive and endoscopic procedures underwent perineal urethrostomy. His history also included Bowen’s disease of the glans penis.

Int Braz J UrolOct 23, 2026Read case
Case ReportUrology

Extending the Graft Harvesting Area in Severe Penoscrotal Hypospadias: The Rainbow Technique.

A 2-year-old with severe penoscrotal hypospadias, a scrotal meatus, bifid scrotum, and chordee exceeding 90° underwent first-stage reconstruction.

Int Braz J UrolOct 23, 2026Read case
Clinical ResearchGeriatrics

Feasibility of a Co-Designed Personalized Cognitive Reablement Program Delivered via Digital Voice Assistants for Older Adults Living With Early-Stage Dementia or Mild Cognitive Impairment: Pilot Randomized Controlled Trial.

This nonblinded pilot randomized controlled trial assessed the feasibility and potential effectiveness of VOICE-COG, a personalized cognitive reablement program delivered through digital voice assistants, in adults aged…

JMIR AgingOct 23, 2026Read summary
Clinical ResearchPediatrics

Silver diamine fluoride versus conventional restorative treatment for dental caries in primary teeth of children: a meta-analysis.

This meta-analysis compared 30% to 38% silver diamine fluoride (SDF) with conventional restorative approaches for caries control in children with carious primary teeth.

Quintessence IntOct 22, 2026Read summary
Clinical ResearchHematology

Concurrent administration of BCMA and GPRC5D CAR T cells for advanced multiple myeloma.

This phase 1 dose-escalation trial evaluated BCMA-directed CAR T-cell therapy MCARH125 alone or infused concurrently with GPRC5D-directed MCARH109 in patients with relapsed or refractory multiple myeloma.

BloodOct 22, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Translational applications and clinical utility of organoids in ovarian cancer: a systematic review.

This systematic review synthesized 13 studies of patient-derived organoids (PDOs) in ovarian cancer, assessing feasibility, histological fidelity, and agreement between organoid drug sensitivity and clinical outcomes.

Cancer Chemother PharmacolOct 22, 2026Read summary
Clinical ResearchPulmonology

Clinical Outcomes and Complications of Extracorporeal Membrane Oxygenation (ECMO) in Adult Patients With COVID-19 in Central and Eastern Europe: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis pooled observational studies of adults with COVID-19 treated with ECMO in Central and Eastern Europe. Twelve studies covered 802 patients from six countries.

Med Sci MonitOct 22, 2026Read summary
Clinical ResearchPediatrics

Clinical performance of resin infiltration and different sealant modalities in noncavitated pits and fissures: a split-mouth randomized controlled trial.

This split-mouth randomized controlled trial compared resin infiltration, two sealant approaches, and their combination for noncavitated occlusal lesions in 128 permanent molars from 32 children aged 7–14 years.

Quintessence IntOct 22, 2026Read summary
Clinical ResearchPsychiatryOpen access

Randomized controlled trial of a group-based smoking cessation intervention for adults with serious mental illness.

This randomized controlled trial evaluated PARQuit in 99 adults with serious mental illness in the United States. Participants received 12 weeks of cessation counseling and pharmacotherapy and were assigned to…

Nicotine Tob ResOct 22, 2026Read summary
Clinical ResearchOrthopedic SurgeryOpen access

Platelet-rich plasma for knee osteoarthritis: a systematic review and meta-analysis of structural outcomes.

This systematic review and meta-analysis assessed imaging-based structural outcomes after platelet-rich plasma (PRP) treatment in people with knee osteoarthritis.

Arch Orthop Trauma SurgOct 22, 2026Read summary
Clinical ResearchPreventive Medicine / Public Health

Combined Chatbot and Counselor Support for Smoking Cessation in China: A Pilot, Mobile-Based, Randomized Controlled Trial.

This two-arm, community-based randomized pilot trial in China assessed chatbot-supported smoking cessation and whether adding personalized counselor support might improve outcomes.

Nicotine Tob ResOct 22, 2026Read summary
Clinical ResearchRheumatology

Ianalumab for the Treatment of Patients with Sjögren's Disease.

Two 52-week, double-blind, randomized, placebo-controlled phase III trials evaluated monthly or less frequent ianalumab in patients with active Sjögren's disease.

N Engl J MedOct 22, 2026Read summary
Case ReportNeurology

Tuberculosis-Associated Longitudinally Extensive Transverse Myelitis.

A 51-year-old man with a year of chronic non-productive cough and about 20 days of fever and headache presented with encephalopathy but no focal neurological deficits.

Am J Case RepOct 22, 2026Read case
Clinical ResearchObstetrics & Gynecology

Maternal and Neonatal Complications in Pregnant Women With Polyendocrine Metabolic Ovarian Syndrome: A Nested Prospective Cohort Study.

This prospective nested cohort study examined associations between polyendocrine metabolic ovarian syndrome (PMOS) and pregnancy outcomes among 3,645 pregnant women with risk factors for hyperglycemia enrolled in an…

Diabetes CareOct 22, 2026Read summary
Clinical ResearchNephrology

Crescents in native kidney biopsies from patients with IgA nephropathy and the risk of recurrence after kidney transplantation: a retrospective cohort study, systematic literature review and meta-analysis of observational studies.

This retrospective cohort study, systematic review and meta-analysis examined whether glomerular crescents in native kidney biopsies predict IgA nephropathy (IgAN) recurrence after kidney transplantation.

J NephrolOct 22, 2026Read summary
Clinical ResearchDermatologyOpen access

Thulium laser-assisted delivery of growth factors for treating androgenetic alopecia - a randomized, controlled, clinical study.

This pilot randomized controlled study evaluated non-ablative fractional laser (NAFL)-assisted delivery of a biomimetic growth factor serum, with or without red light therapy, in patients with androgenetic alopecia.

Lasers Med SciOct 22, 2026Read summary
Clinical ResearchGeneral SurgeryOpen access

The effect of telephone-based education and counselling on stoma adjustment and complication severity in individuals with a colostomy: a randomised controlled trial.

This randomised controlled trial evaluated telephone-based education and counselling for people with a colostomy, compared with routine stoma care.

Support Care CancerOct 22, 2026Read summary
Clinical ResearchPreventive Medicine / Public HealthOpen access

Avatar-led digital health intervention for sexual and gender minority young adult smoking cessation: randomized controlled pilot trial.

This randomized controlled pilot trial compared EQQUAL, an Acceptance and Commitment Therapy-based digital smoking cessation program tailored for sexual and gender minority (SGM) young adults, with Smokefree.gov.

Nicotine Tob ResOct 22, 2026Read summary

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