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1998 articles
October 202624
Combined transcutaneous electrical nerve stimulation and low-level laser photobiomodulation for postoperative pain after cesarean section: A randomized controlled trial.
This randomized controlled trial compared combined transcutaneous electrical nerve stimulation (TENS) and low-level laser photobiomodulation (PBM) with TENS alone, placebo, and control for postoperative recovery after…
Bolus-only versus bolus plus continuous infusion hydromorphone for refractory cancer pain: a prospective, multicenter, randomized noninferiority trial.
This prospective, multicenter, randomized noninferiority trial compared bolus-only patient-controlled intravenous hydromorphone analgesia with bolus plus continuous infusion in patients with refractory cancer pain.
A self-controlled case series to evaluate the effects of clinical trial eligibility criteria on biologic-associated reductions in severe asthma exacerbations: an analysis of the CHRONICLE study.
This study examined whether eligibility criteria used in biologic trials identify adults with severe asthma who are more likely to benefit.
A case of lysozyme-induced nephropathy with improved renal function following treatment for chronic myelomonocytic leukemia.
A 75-year-old man with longstanding diabetes presented with weight loss and progressive anemia and was diagnosed with chronic myelomonocytic leukemia (CMML).
Determining the minimal important difference of EQ-5D-5 L utility values in CIDP patients using data from a large clinical trial.
This analysis of data from the ADHERE randomized controlled trial estimated the minimal important difference (MID) in EQ-5D-5 L utility values for patients with chronic inflammatory demyelinating polyradiculoneuropathy…
Early exercise therapy for acute nephrotic syndrome: a randomised clinical trial.
This single-centre randomised controlled trial assessed early exercise therapy in hospitalised adults receiving glucocorticoids for acute nephrotic syndrome.
Anbalcabtagene autoleucel (PD-1 and TIGIT knockdown CD19 CAR T-cell therapy) for relapsed or refractory LBCL: the CRC01-01 trial.
The multicenter phase 1/2 CRC01-01 trial evaluated anbalcabtagene autoleucel, a CD19 CAR T-cell therapy with PD-1 and TIGIT knockdown, in patients with relapsed or refractory large B-cell lymphoma.
Effectiveness of tocilizumab monotherapy for IgG4-related disease-like features caused by idiopathic multicentric Castleman's disease: a case-based review.
A 68-year-old woman presented with dyspnea associated with a recurrent laryngeal tumor, pulmonary consolidation, mediastinal and axillary lymphadenopathy, sclerosing mesenteritis, and retroperitoneal fibrosis.
Firstline treatment with ruxolitinib versus best available therapy in patients with polycythemia vera: results from the randomized RuxoBEAT trial.
The multicenter randomized RuxoBEAT trial compared first-line ruxolitinib (RUX) with best available therapy (BAT) in patients with polycythemia vera.
Safety and immunogenicity of the 24-valent pneumococcal conjugate vaccine in healthy Chinese adults: two single-center, randomized, double-blind Phase 1 and Phase 2 trials.
Two single-center, randomized, double-blind Phase 1 and Phase 2 trials assessed the safety and immunogenicity of a 24-valent pneumococcal conjugate vaccine (PCV24) in healthy Chinese adults aged 18 years or older.
Novel Imaging Techniques Prior to Surgical Management of Invasive Bladder Cancer: A Systematic Review.
This PRISMA-guided systematic review assessed novel imaging for detecting muscle invasion and nodal disease before surgical management of invasive bladder cancer. It included 33 studies encompassing 4,689 patients.
Minimally invasive management of pulmonary artery bleed in robotic left upper lobectomy.
A patient undergoing robotic left upper lobectomy for a Pancoast tumour developed an intraoperative pulmonary artery bleed.
Molecular-genetic mechanisms of cerebral arteriovenous malformations: A systematic review of germline, somatic and experimental evidence.
This systematic review synthesised human genetic, molecular, and experimental evidence on cerebral arteriovenous malformation (AVM) formation, clinical course, and potential therapeutic targets.
Prediction of death by neurologic criteria in patients with non-traumatic acute brain injury: a systematic review and meta-analysis.
This systematic review and meta-analysis examined predictors of death by neurologic criteria (DNC) after non-traumatic acute brain injury.
Effects of exposure to negative and positive social media content about vaping and nicotine addiction on beliefs and intentions to use e-cigarettes among young adults in the United States: results from a randomized controlled experiment.
This randomized controlled experiment assigned 1,816 young adults in the United States to view real, publicly accessible social media videos presenting nicotine addiction positively, negatively, or in unrelated control…
Hyponatremic-Hypertensive Syndrome as a Rare Manifestation of Renovascular Hypertension: A Case Series.
Two girls, aged 4 and 9 years, presented with severe hypertension and electrolyte disturbances, including hyponatremia and hypokalemia, with elevated renin-aldosterone activity.
Clinical safety, tolerability, and efficacy of fospropofol disodium for sedation: a systematic review.
This systematic review and meta-analysis assessed randomized trials of fospropofol for procedural and ICU sedation. It included 10 studies: six procedural-sedation trials and four ICU-sedation trials.
Impact of remote management using patient-reported outcomes on pain and anxiety after breast biopsy: the BIO-PSY randomized controlled trial.
The BIO-PSY French, single-centre, open-label randomised controlled trial assessed whether remote patient-reported outcome (PRO) monitoring with tailored interventions improved pain and anxiety after breast biopsy.
Patterns and predictive factors of hearing loss following microvascular decompression for hemifacial spasm: a systematic review.
This systematic review and meta-analysis assessed the prevalence, patterns, and potential risk factors for hearing loss after microvascular decompression for hemifacial spasm.
Clinical and radiographic success of bioflex versus stainless steel crowns using the hall technique in primary molars: a 12-month randomized controlled trial.
This two-arm randomized controlled trial compared BioFlex crowns (BFCs) with stainless-steel crowns (SSCs), both placed using the Hall Technique, in healthy children aged 4–6 years with carious mandibular second primary…
Drug-coated balloons in coronary disease: meta-analysis comparing sirolimus- and paclitaxel-coated technologies.
This systematic review and meta-analysis compared sirolimus-coated balloons (SCBs) with paclitaxel-coated balloons (PCBs) for coronary interventions.
Efficacy and Safety of Argatroban as an Adjunct to Antiplatelet Therapy in Ischemic Stroke: An Updated Systematic Review and Meta-analysis.
This systematic review and meta-analysis assessed argatroban added to antiplatelet therapy versus control in acute ischemic stroke.
Administration-order effects in head-to-head comparisons of the EQ-5D-3L and EQ-5D-5L descriptive systems: evidence from a randomised general-population panel in Great Britain.
This randomised study in a general-population panel in Great Britain examined whether administration order affects comparisons of the EQ-5D-3L and EQ-5D-5L.
Antidopaminergic Medications and Clinical Outcomes in Huntington Disease: Evidence From the PROOF-HD Placebo-Controlled Trial.
This post hoc analysis of the placebo arm of the randomized PROOF-HD trial examined associations between antidopaminergic medication (ADM) use and clinical outcomes in adults with Huntington disease.
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