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1998 articles

October 202624

Clinical ResearchOncology (Medical)Open access

Association between cancer cachexia and treatment-related adverse outcomes in patients with gastrointestinal cancers: a systematic review and meta-analysis.

This systematic review and meta-analysis examined cohort studies of cancer cachexia and treatment-related outcomes in patients with gastrointestinal cancers.

Support Care CancerOct 23, 2026Read summary
Clinical ResearchDermatologyOpen access

Fractional CO₂ laser combined with intradermal and topical platelet-rich plasma for hypertrophic scars: a randomized controlled trial.

This prospective, randomized, assessor-blinded trial compared fractional CO₂ laser plus intradermal and topical platelet-rich plasma (PRP) with laser plus saline in 120 patients with hypertrophic scars.

Lasers Med SciOct 23, 2026Read summary
Case ReportUrology

Robot-Assisted Radical Prostatectomy in a Post-Enucleation Gland.

A 64-year-old man was found to have right-lobe ISUP grade 3 prostate adenocarcinoma after HoLEP for benign prostatic obstruction. PSA was 0.51 ng/mL, and MRI showed a 0.4 cm PI-RADS 4 lesion.

Int Braz J UrolOct 23, 2026Read case
Case ReportInfectious Diseases

Streptococcus constellatus-Associated Lemierre Syndrome Presenting With Cavitating Septic Pulmonary Emboli Managed by Video-Assisted Thoracoscopy.

A previously healthy 25-year-old man presented with a week of dyspnea, productive cough, fever, and hemoptysis, with severe hypoxemia and respiratory distress.

Am J Case RepOct 23, 2026Read case
Clinical ResearchRadiology (Diagnostic)

The entorhinal cortex atrophy score for diagnostic distinction between phases of the Alzheimer's disease continuum.

This systematic review assessed the Entorhinal Cortex Atrophy (ERICA) visual score for distinguishing subjective cognitive decline (SCD), mild cognitive impairment (MCI), and Alzheimer’s disease (AD) dementia.

Arq NeuropsiquiatrOct 23, 2026Read summary
Case ReportPediatrics

Fosfomycin-induced liver injury in a 17-year-old patient: A case report.

A previously healthy 17-year-old male developed nausea, vomiting, fever, progressive epigastric pain, fatigue, and malaise.

Am J Health Syst PharmOct 23, 2026Read case
Clinical ResearchGastroenterology

Gut virome remodeling after fecal microbiota transplantation is associated with virus-bacteria co-variation and metabolic response in obesity and type 2 diabetes.

This randomized controlled trial examined longitudinal fecal virome and bacteriome changes after fecal microbiota transplantation (FMT) in people with obesity and type 2 diabetes.

Gut MicrobesOct 23, 2026Read summary
Clinical ResearchObstetrics & Gynecology

The Impact of Telemedicine Interventions on Maternal and Fetal Outcomes in Women With Gestational Diabetes: Systematic Review and Meta-Analysis of Randomized Controlled Trials.

This systematic review and meta-analysis pooled 23 randomized controlled trials involving 3055 women with gestational diabetes to assess telemedicine and maternal and fetal outcomes.

J Med Internet ResOct 23, 2026Read summary
Case ReportInfectious Diseases

Fatal Occupational Leptospirosis in a Beef Cattle Farmer: Case Report and Epidemiological Investigation.

A 56-year-old beef cattle farmer in Lombardy, Italy, died from occupational leptospirosis. Testing identified a strain of serogroup Javanica, with a microscopic agglutination test titre of 1:3,200 against serovar Poi.

Med LavOct 23, 2026Read case
Case ReportNeurologyOpen access

Spontaneous regression of post-traumatic syringomyelia: longitudinal mr imaging demonstrating a dynamic disease course.

A 69-year-old patient with post-traumatic cervicothoracic syringomyelia presented with occipital headaches, dizziness, and subjective upper-extremity weakness.

Spinal Cord Ser CasesOct 23, 2026Read case
Clinical ResearchOncology (Medical)Open access

Extracorporeal photopheresis for the treatment of steroid-refractory immune related adverse events from immune checkpoint inhibitor therapy: a multi-center phase Ib/II clinical trial.

This prospective, single-arm, non-randomized phase Ib/II multicentre trial evaluated extracorporeal photopheresis (ECP) for steroid-refractory immune-related adverse events (irAEs) in 30 patients receiving immune…

Nat CommunOct 23, 2026Read summary
Clinical ResearchPreventive Medicine / Public Health

Hematological and biochemical responses to three doses of caffeine during the CrossFit® workout: a randomized, double-blind, crossover trial.

This randomized, double-blind, placebo-controlled crossover trial examined hematological and biochemical responses to caffeine during a 17-minute CrossFit® workout in 26 moderately trained athletes.

J Int Soc Sports NutrOct 23, 2026Read summary
Clinical ResearchPediatricsOpen access

Immediate vs delayed extubation after pediatric liver transplantation: a systematic review and meta-analysis.

This systematic review and meta-analysis compared immediate operating-room extubation with delayed extubation after pediatric orthotopic liver transplantation.

Eur J PediatrOct 23, 2026Read summary
Clinical ResearchEndocrinologyOpen access

Skeletal effects of GLP-1 receptor agonist therapy in adults with overweight or obesity: a systematic review.

This systematic review examined randomized evidence on bone mineral density (BMD) and bone-turnover markers in adults with overweight or obesity receiving GLP-1 receptor agonists.

Arch OsteoporosOct 23, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Protective effect of N-acetylcysteine on oxaliplatin-induced peripheral neuropathy in colorectal cancer: a randomized controlled trial.

This randomized controlled trial evaluated oral N-acetylcysteine (NAC) for preventing oxaliplatin-induced peripheral neuropathy in 46 patients with stage III or high-risk stage II colorectal cancer receiving adjuvant…

Cancer Chemother PharmacolOct 23, 2026Read summary
Clinical ResearchInfectious Diseases

Evaluation of the Achievement of a Pharmacodynamic Target of Piperacillin-Tazobactam for the Population With Obesity: An Open Randomized Controlled Feasibility Study (TAZO-OBESITY Trial).

The open-label randomized feasibility trial TAZO-OBESITY compared standard with prolonged piperacillin-tazobactam infusions in patients with obesity (BMI ≥30 kg/m²).

Fundam Clin PharmacolOct 23, 2026Read summary
Clinical ResearchEmergency Medicine

Jidesheng Snake Pills as Adjunctive Therapy for Snakebite: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

This systematic review and meta-analysis assessed randomized evidence for Jidesheng Snake Pills as adjunctive treatment for snakebite. Five unique trials involving 458 participants were included.

J Vis ExpOct 23, 2026Read summary
Case ReportUrology

Robotic Totally Intracorporeal Bilateral Boari Flap Reconstruction for Complex Bilateral Ureteral Strictures: A Step-by-Step Technique.

A 42-year-old woman with complex bilateral mid- and distal ureteral strictures underwent robotic, totally intracorporeal bilateral Boari flap reconstruction.

Int Braz J UrolOct 23, 2026Read case
Clinical ResearchGeneral SurgeryOpen access

Prophylactic neurectomy versus nerve preservation in open inguinal hernia repair for prevention of chronic postoperative inguinal pain (CPIP): a systematic review and meta-analysis.

This systematic review and meta-analysis assessed prophylactic neurectomy versus nerve preservation in adults undergoing elective open anterior inguinal hernia repair, including 17 randomized trials.

HerniaOct 23, 2026Read summary
Clinical ResearchNeurologyOpen access

STN-SNr co-stimulation in Parkinson's disease: a systematic review and meta-analysis of motor and freezing-of-gait outcomes.

This systematic review and meta-analysis assessed whether adding substantia nigra pars reticulata stimulation to subthalamic nucleus deep brain stimulation improves motor function or freezing of gait in people with…

Neurol SciOct 23, 2026Read summary
Clinical ResearchHematologyOpen access

The perceptions of hematopoietic stem cell transplantation decision-making in patients with hematologic malignancies: a qualitative systematic review.

This qualitative systematic review synthesized research on how patients with hematologic malignancies perceive decisions about hematopoietic stem cell transplantation (HSCT).

Support Care CancerOct 23, 2026Read summary
Clinical ResearchGeriatrics

A Methodological Framework for a Large Language Model Virtual Companion for Older Adults at Risk of Social Isolation.

This paper presents a methodological framework for developing and evaluating a large language model (LLM)-driven virtual companion for older adults at risk of social isolation.

J Vis ExpOct 23, 2026Read summary
Case ReportPsychiatry

Psychopathological and neuropsychological sequelae in children victimised by intimate partner violence: a clinical case series.

A clinical case series assessed four children aged 5–9 with documented exposure to intimate partner violence, including witnessing violence and, in some cases, direct abuse.

Eur J PsychotraumatolOct 23, 2026Read case
Case ReportUrology

Perineal Urethrostomy After Urethral Stricture: Step-by-Step Surgical Technique.

A 73-year-old man with complex, recurrent urethral stricture after multiple reconstructive and endoscopic procedures underwent perineal urethrostomy. His history also included Bowen’s disease of the glans penis.

Int Braz J UrolOct 23, 2026Read case

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