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2000 articles

September 202624

Case ReportOrthopedic Surgery

Primary Hyperparathyroidism Presenting as a Distal Femur Pathologic Fracture in an Adolescent: A Case Report.

A 17-year-old boy presented with a pathologic fracture of the distal femur, accompanied by bilateral distal femoral metadiaphyseal lytic lesions.

JBJS Case ConnectSep 24, 2026Read case
Case ReportOrthopedic Surgery

Radioulnar Synostosis After Isolated Undisplaced Distal Ulna Fracture: A Rare Case Report and Review of the Literature.

A 50-year-old man presented with restricted forearm rotation due to radioulnar synostosis, which developed 15 months after an isolated undisplaced distal ulna fracture.

JBJS Case ConnectSep 24, 2026Read case
Case ReportGastroenterology

Giant choledochal cyst - type VI B.

A man in his early 20s presented with jaundice, abdominal pain, and right upper quadrant fullness. Imaging revealed a type VI B choledochal cyst, characterized by significant dilatation of the cystic duct and common…

BMJ Case RepSep 24, 2026Read case
Clinical ResearchHematology

Etuvetidigene Autotemcel for the Treatment of Wiskott-Aldrich Syndrome.

This multicenter clinical trial evaluated the safety and efficacy of etuvetidigene autotemcel (etu-cel) in patients with Wiskott-Aldrich syndrome, integrating data from two studies and an expanded-access program.

N Engl J MedSep 24, 2026Read summary
Clinical ResearchOphthalmology

Impact of different intraocular pressures during cataract surgery on retinal perfusion in eyes with diabetic retinopathy: randomized clinical trial.

This randomized clinical trial investigated the effects of low (20 mm Hg) versus high (55 mm Hg) intraocular pressure during cataract surgery on retinal perfusion in patients with nonproliferative diabetic retinopathy.

J Cataract Refract SurgSep 24, 2026Read summary
Case ReportOrthopedic Surgery

Anterior Hip Dislocation with Testicular Interposition: A Case Report.

A 48-year-old man experienced severe inguinal pain and hip immobility following a high-energy injury. Examination revealed scrotal invagination and a nonpalpable testis, with imaging showing anterior hip subluxation and…

JBJS Case ConnectSep 24, 2026Read case
Clinical ResearchOphthalmology

Optical quality in decentration of intraocular lenses: updated systematic review.

This systematic review evaluated the impact of intraocular lens (IOL) decentration on optical quality across various IOL designs, including monofocal, EDOF, multifocal, and toric lenses.

J Cataract Refract SurgSep 24, 2026Read summary
Clinical ResearchNeurology

Brain-motor behavior coupling during walking while negotiating obstacle: A systematic review.

This systematic review examined cortical activity alongside gait during obstacle negotiation in adults, using a brain–motor behavior framework.

Neurosci Biobehav RevSep 24, 2026Read summary
Case ReportMedical Genetics

Mild Phenotype in Functionally Validated STAT1 Gain-of-Function Disease Due to a Novel DNA-Binding Variant.

A case report describes four patients with STAT1 gain-of-function disease, focusing on three related individuals with a novel p.Leu400Pro variant.

Scand J ImmunolSep 24, 2026Read case
Clinical ResearchHematology

Phase 1 Study of Anito-cel, a d-Domain BCMA CAR T Cell for Refractory or Recurrent Myeloma.

This phase 1 multicenter study evaluated the safety and efficacy of anitocabtagene autoleucel (anito-cel), a BCMA-directed CAR T-cell therapy, in 40 patients with relapsed or refractory multiple myeloma.

N Engl J MedSep 24, 2026Read summary
Case ReportPlastic Surgery

Salvaging a submental flap.

A 50-year-old man underwent surgery for carcinoma of the gingivobuccal sulcus, followed by reconstruction using a submental artery-based island flap (SMIF).

BMJ Case RepSep 24, 2026Read case
Case ReportOrthopedic Surgery

Challenging Removal of Intramedullary Nails: Description of 2 Techniques With Proposal to Classify Nail Extraction Methods.

This report details two cases of intramedullary nail removal. The first involved an intact, incarcerated short proximal femoral nail successfully extracted without creating an additional bone window, followed by hip…

JBJS Case ConnectSep 24, 2026Read case
Clinical ResearchObstetrics & GynecologyOpen access

Predictors of Quit Attempts and Successful Smoking Abstinence in Pregnancy: An Exploratory Analysis of a Pooled Clinical Trial Dataset.

This multicenter randomized controlled trial analyzed pooled data from 1409 pregnant women to identify predictors of quit attempts and smoking abstinence.

Nicotine Tob ResSep 24, 2026Read summary
Clinical ResearchPhysical Medicine & Rehabilitation

Do blood flow restriction exercises offer additional benefits when compared to conventional exercises in musculoskeletal rehabilitation? A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the effects of low-load exercise with blood flow restriction (LLE-BFR) versus low-load exercise (LLE) and high-load exercise (HLE) in individuals with musculoskeletal…

Br J Sports MedSep 24, 2026Read summary
Case ReportHematology

Immune Thrombotic Thrombocytopenic Purpura: Diagnosis and Management.

A middle-aged patient with a history of immune-mediated thrombotic thrombocytopenic purpura (iTTP) presented with a relapse characterized by thrombocytopenia and microangiopathic hemolytic anemia.

Am J NursSep 24, 2026Read case
Case ReportPsychiatry

Summer-pattern seasonal affective disorder: A case study and implications for primary care.

A 35-year-old woman presented with a 3-year history of summer-onset depression, characterized by irritability, insomnia, appetite loss, and psychomotor agitation.

JAAPASep 24, 2026Read case
Clinical ResearchPsychiatry

Zuclopenthixol acetate for acute schizophrenia and similar major mental illnesses.

This systematic review and meta-analysis evaluated the effectiveness of zuclopenthixol acetate for managing acute behavioral disturbances in 714 participants with acute schizophrenia and similar major mental illnesses.

Cochrane Database Syst RevSep 24, 2026Read summary
Clinical ResearchPediatrics

Parental awareness, attitudes and decision-making of off-label use in children: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated parental awareness and attitudes towards off-label medication use in children. In seven studies, the pooled parental awareness rate was found to be 20.2%.

BMJ Paediatr OpenSep 24, 2026Read summary
Clinical ResearchCardiology

Mitochondrial DNA methylation as a bridge: Linking indoor air purification to alleviated cardiovascular impairments in young adults.

This randomized, double-blind crossover trial examined whether mitochondrial DNA (mtDNA) methylation was associated with fine particulate matter (PM2.5) exposure and cardiovascular indicators in 38 healthy young adults.

Environ ResSep 24, 2026Read summary
Clinical ResearchOncology (Medical)

Structured exercise interventions and survival outcomes in patients with cancer: systematic review and meta-analysis of randomised controlled trials.

This systematic review and meta-analysis evaluated the impact of structured exercise interventions on survival outcomes in cancer patients.

Br J Sports MedSep 24, 2026Read summary
Clinical ResearchObstetrics & GynecologyOpen access

Prenatal allostatic load and adverse pregnancy outcomes: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the relationship between prenatal allostatic load (AL) and adverse pregnancy outcomes (APOs) in a population of 8,795 pregnant women.

PeerJSep 24, 2026Read summary
Case ReportNeurosurgery

Microvascular decompression for long-standing oculomotor nerve palsy due to compression by fetal-type posterior communicating artery.

A woman with a 2-year history of left-sided ptosis and binocular horizontal diplopia was diagnosed with oculomotor nerve palsy due to compression from a fetal-type posterior communicating artery.

BMJ Case RepSep 24, 2026Read case
Clinical ResearchCardiology

Opposite seasonal variation in nighttime and morning blood pressure: a longitudinal study of patients with hypertension.

This longitudinal study examined seasonal variations in nighttime and morning blood pressure (BP) among 419 hypertensive patients using home blood pressure monitoring.

Am J HypertensSep 24, 2026Read summary
Case ReportOrthopedic Surgery

Extraneural ganglion cyst causing foot drop.

A male in his late 50s presented with a swelling on the lateral aspect of the right proximal lower leg, accompanied by progressive ankle dorsiflexion weakness and sensory loss on the dorsum of the foot.

BMJ Case RepSep 24, 2026Read case

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