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1998 articles

October 202624

Clinical ResearchPreventive Medicine / Public Health

Effects of exposure to negative and positive social media content about vaping and nicotine addiction on beliefs and intentions to use e-cigarettes among young adults in the United States: results from a randomized controlled experiment.

This randomized controlled experiment assigned 1,816 young adults in the United States to view real, publicly accessible social media videos presenting nicotine addiction positively, negatively, or in unrelated control…

Nicotine Tob ResOct 22, 2026Read summary
Clinical ResearchHematologyOpen access

Firstline treatment with ruxolitinib versus best available therapy in patients with polycythemia vera: results from the randomized RuxoBEAT trial.

The multicenter randomized RuxoBEAT trial compared first-line ruxolitinib (RUX) with best available therapy (BAT) in patients with polycythemia vera.

Blood Cancer JOct 22, 2026Read summary
Clinical ResearchUrologyOpen access

Novel Imaging Techniques Prior to Surgical Management of Invasive Bladder Cancer: A Systematic Review.

This PRISMA-guided systematic review assessed novel imaging for detecting muscle invasion and nodal disease before surgical management of invasive bladder cancer. It included 33 studies encompassing 4,689 patients.

Curr Urol RepOct 22, 2026Read summary
Clinical ResearchCardiologyOpen access

Drug-coated balloons in coronary disease: meta-analysis comparing sirolimus- and paclitaxel-coated technologies.

This systematic review and meta-analysis compared sirolimus-coated balloons (SCBs) with paclitaxel-coated balloons (PCBs) for coronary interventions.

BMC Cardiovasc DisordOct 22, 2026Read summary
Case ReportCardiothoracic Surgery

Minimally invasive management of pulmonary artery bleed in robotic left upper lobectomy.

A patient undergoing robotic left upper lobectomy for a Pancoast tumour developed an intraoperative pulmonary artery bleed.

Multimed Man Cardiothorac SurgOct 22, 2026Read case
Case ReportPediatrics

Hyponatremic-Hypertensive Syndrome as a Rare Manifestation of Renovascular Hypertension: A Case Series.

Two girls, aged 4 and 9 years, presented with severe hypertension and electrolyte disturbances, including hyponatremia and hypokalemia, with elevated renin-aldosterone activity.

Am J Case RepOct 22, 2026Read case
Clinical ResearchPulmonology

Clinical Outcomes and Complications of Extracorporeal Membrane Oxygenation (ECMO) in Adult Patients With COVID-19 in Central and Eastern Europe: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis pooled observational studies of adults with COVID-19 treated with ECMO in Central and Eastern Europe. Twelve studies covered 802 patients from six countries.

Med Sci MonitOct 22, 2026Read summary
Clinical ResearchOncology (Medical)

Anbalcabtagene autoleucel (PD-1 and TIGIT knockdown CD19 CAR T-cell therapy) for relapsed or refractory LBCL: the CRC01-01 trial.

The multicenter phase 1/2 CRC01-01 trial evaluated anbalcabtagene autoleucel, a CD19 CAR T-cell therapy with PD-1 and TIGIT knockdown, in patients with relapsed or refractory large B-cell lymphoma.

BloodOct 22, 2026Read summary
Clinical ResearchPreventive Medicine / Public HealthOpen access

Administration-order effects in head-to-head comparisons of the EQ-5D-3L and EQ-5D-5L descriptive systems: evidence from a randomised general-population panel in Great Britain.

This randomised study in a general-population panel in Great Britain examined whether administration order affects comparisons of the EQ-5D-3L and EQ-5D-5L.

Qual Life ResOct 22, 2026Read summary
Clinical ResearchNephrology

Crescents in native kidney biopsies from patients with IgA nephropathy and the risk of recurrence after kidney transplantation: a retrospective cohort study, systematic literature review and meta-analysis of observational studies.

This retrospective cohort study, systematic review and meta-analysis examined whether glomerular crescents in native kidney biopsies predict IgA nephropathy (IgAN) recurrence after kidney transplantation.

J NephrolOct 22, 2026Read summary
Clinical ResearchPulmonologyOpen access

A self-controlled case series to evaluate the effects of clinical trial eligibility criteria on biologic-associated reductions in severe asthma exacerbations: an analysis of the CHRONICLE study.

This study examined whether eligibility criteria used in biologic trials identify adults with severe asthma who are more likely to benefit.

Eur Respir JOct 22, 2026Read summary
Clinical ResearchGeriatrics

Agreement Between In-Person and Telephone Application of the Informant Questionnaire on Cognitive Decline in the Elderly.

This methodological study assessed agreement between in-person and telephone administration of the Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE), completed by caregivers or family members of older…

PsychogeriatricsOct 22, 2026Read summary
Clinical ResearchDermatologyOpen access

Thulium laser-assisted delivery of growth factors for treating androgenetic alopecia - a randomized, controlled, clinical study.

This pilot randomized controlled study evaluated non-ablative fractional laser (NAFL)-assisted delivery of a biomimetic growth factor serum, with or without red light therapy, in patients with androgenetic alopecia.

Lasers Med SciOct 22, 2026Read summary
Clinical ResearchNeurologyOpen access

Prediction of death by neurologic criteria in patients with non-traumatic acute brain injury: a systematic review and meta-analysis.

This systematic review and meta-analysis examined predictors of death by neurologic criteria (DNC) after non-traumatic acute brain injury.

BMC NeurolOct 22, 2026Read summary
Clinical ResearchOrthopedic SurgeryOpen access

Platelet-rich plasma for knee osteoarthritis: a systematic review and meta-analysis of structural outcomes.

This systematic review and meta-analysis assessed imaging-based structural outcomes after platelet-rich plasma (PRP) treatment in people with knee osteoarthritis.

Arch Orthop Trauma SurgOct 22, 2026Read summary
Clinical ResearchPreventive Medicine / Public Health

Combined Chatbot and Counselor Support for Smoking Cessation in China: A Pilot, Mobile-Based, Randomized Controlled Trial.

This two-arm, community-based randomized pilot trial in China assessed chatbot-supported smoking cessation and whether adding personalized counselor support might improve outcomes.

Nicotine Tob ResOct 22, 2026Read summary
Case ReportNephrologyOpen access

A case of lysozyme-induced nephropathy with improved renal function following treatment for chronic myelomonocytic leukemia.

A 75-year-old man with longstanding diabetes presented with weight loss and progressive anemia and was diagnosed with chronic myelomonocytic leukemia (CMML).

CEN Case RepOct 22, 2026Read case
Clinical ResearchNeurologyOpen access

Determining the minimal important difference of EQ-5D-5 L utility values in CIDP patients using data from a large clinical trial.

This analysis of data from the ADHERE randomized controlled trial estimated the minimal important difference (MID) in EQ-5D-5 L utility values for patients with chronic inflammatory demyelinating polyradiculoneuropathy…

Qual Life ResOct 22, 2026Read summary
Clinical ResearchInfectious Diseases

Safety and immunogenicity of the 24-valent pneumococcal conjugate vaccine in healthy Chinese adults: two single-center, randomized, double-blind Phase 1 and Phase 2 trials.

Two single-center, randomized, double-blind Phase 1 and Phase 2 trials assessed the safety and immunogenicity of a 24-valent pneumococcal conjugate vaccine (PCV24) in healthy Chinese adults aged 18 years or older.

Expert Rev VaccinesOct 22, 2026Read summary
Clinical ResearchNeurologyOpen access

Efficacy and Safety of Argatroban as an Adjunct to Antiplatelet Therapy in Ischemic Stroke: An Updated Systematic Review and Meta-analysis.

This systematic review and meta-analysis assessed argatroban added to antiplatelet therapy versus control in acute ischemic stroke.

Eur J Clin PharmacolOct 22, 2026Read summary
Clinical ResearchGastroenterologyOpen access

Patients with MASH experience worse health-related quality of life: a multinational real-world study using LiverMultiScan.

This multinational real-world randomised controlled trial examined health-related quality of life (HRQoL) and liver MRI markers in 802 people with suspected MASLD/MASH across four European countries.

Qual Life ResOct 22, 2026Read summary
Clinical ResearchGeneral SurgeryOpen access

The effect of telephone-based education and counselling on stoma adjustment and complication severity in individuals with a colostomy: a randomised controlled trial.

This randomised controlled trial evaluated telephone-based education and counselling for people with a colostomy, compared with routine stoma care.

Support Care CancerOct 22, 2026Read summary
Clinical ResearchNephrology

Early exercise therapy for acute nephrotic syndrome: a randomised clinical trial.

This single-centre randomised controlled trial assessed early exercise therapy in hospitalised adults receiving glucocorticoids for acute nephrotic syndrome.

J NephrolOct 22, 2026Read summary
Clinical ResearchPediatrics

Clinical performance of resin infiltration and different sealant modalities in noncavitated pits and fissures: a split-mouth randomized controlled trial.

This split-mouth randomized controlled trial compared resin infiltration, two sealant approaches, and their combination for noncavitated occlusal lesions in 128 permanent molars from 32 children aged 7–14 years.

Quintessence IntOct 22, 2026Read summary

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