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2000 articles
September 202624
Lumbar spinal brucellosis presenting as an atypical epidural abscess.
A man in his 50s presented with low back pain and lower limb radiculopathy. MRI revealed a ventral epidural collection at L4-L5, resembling a sequestered disc fragment, without significant vertebral or disc involvement.
Sarcopenia in Indian adults with type 2 diabetes: a systematic review and meta-analysis of prevalence and associated factors.
This systematic review and meta-analysis assessed the prevalence of sarcopenia among Indian adults with type 2 diabetes mellitus (T2DM).
The Effect of Carbetocin on Cardiac Repolarization: A Randomized, Placebo- and Positive-Controlled QT/QTc Study in Healthy Adults.
This randomized controlled trial assessed the impact of a supratherapeutic dose of carbetocin on cardiac repolarization in 42 healthy adults.
Uveitis as a class effect of Bruton tyrosine kinase inhibitors: ibrutinib and zanubrutinib ocular toxicity.
A man in his early 50s with Waldenström macroglobulinaemia developed posterior uveitis while on ibrutinib, characterized by vitreous and retinal infiltrates.
Rotational thromboelastometry guided transfusion in venom-induced consumptive coagulopathy following a haemotoxic snakebite.
A woman in her 30s presented with severe haemotoxic snake envenoming and venom-induced consumptive coagulopathy (VICC), leading to early multiorgan involvement.
GLP-1 receptor agonist exposure in the periconceptional period and adverse obstetric outcomes: A systematic review and meta-analysis.
This systematic review and random-effects meta-analysis examined observational studies comparing pregnancies with and without GLP-1 receptor agonist exposure during pregnancy or within six months before a positive…
Retatrutide in adults with obesity and type 2 diabetes (TRIUMPH-2): a double-blind, parallel-group, randomised, placebo-controlled, phase 3 trial.
TRIUMPH-2 was a double-blind, parallel-group, randomised, placebo-controlled phase 3 trial at 92 centres in eight countries. It assessed once-weekly retatrutide in adults with obesity and type 2 diabetes.
Autologous retinal transplant for macular hole in retinal detachment following bag-intraocular lens complex dislocation.
An elderly patient in their late 80s presented with total retinal detachment and a macular hole following pars plana vitrectomy for a dislocated capsular bag-intraocular lens complex.
Unveiling the Prognostic Power of Circulating Tumor DNA in Multiple Myeloma: A Systematic Review and Updated Meta-Analysis.
This systematic review and meta-analysis evaluated the prognostic significance of circulating tumor DNA (ctDNA) in 948 patients with multiple myeloma (MM).
Efficacy of transcranial alternating current stimulation on cognitive function in patients with dementia: a systematic review and meta-analysis of randomized controlled trials.
This systematic review and meta-analysis evaluated the efficacy of transcranial alternating current stimulation (tACS) on cognitive function in 357 dementia patients across 9 randomized controlled trials.
Efficacy and safety of T-DXd versus Other HER2-targeted therapies in second-line and later settings for HER2-positive metastatic breast cancer: A Bayesian network meta-analysis.
This Bayesian network meta-analysis evaluated the efficacy and safety of T-DXd compared to other HER2-targeted therapies in 3,339 patients with HER2-positive metastatic breast cancer after trastuzumab-based therapy.
Designing Youth Early Intervention in Psychosis Services: A Secondary Framework Synthesis of Organisational Recommendations.
This systematic review synthesized organizational recommendations from 26 international guidelines on early intervention in psychosis (EIP) for youth.
Petrelintide, a human amylin analogue for the treatment of obesity (ZUPREME 1): a randomised, double-blind, placebo-controlled, phase 2 trial.
This multicentre, randomised, double-blind, placebo-controlled phase 2 trial assessed once-weekly petrelintide in adults with obesity or overweight with hypertension or dyslipidaemia, without type 2 diabetes.
A Heterozygous Variant in the GABBR2 Gene in a Girl With Clinical Classic Rett Syndrome.
A girl diagnosed with classic Rett syndrome exhibited developmental stagnation, loss of purposeful hand use, stereotypic movements, autonomic dysfunction, and behavioral issues.
Longest surviving patient with a homozygous splice-altering EGFR pathogenic variant presenting with skin autoinflammation and a Bartter-like salt-losing tubulopathy.
An adolescent patient with a Bartter-like phenotype presented with progressive nephrocalcinosis, hypercalciuria, and skin autoinflammation.
Segmental sternal resection for metastatic ovarian cancer: surgical technique and clinical outcome.
Isolated sternal recurrence from ovarian cancer is exceptionally rare, and its optimal surgical management remains poorly defined.
Subcutaneous infliximab for maintenance therapy in children and adolescents with inflammatory bowel disease: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the effectiveness and safety of subcutaneous infliximab for maintenance therapy in children and adolescents with inflammatory bowel disease.
Stroke mimic caused by severe hypomagnesemia: a case report and literature review.
A patient with a history of transient neurological deficits presented with stroke-like symptoms, including hemiparesis and aphasia. The patient was on Proton Pump Inhibitors and Metformin.
Combined repetitive transcranial magnetic stimulation and mirror therapy for upper limb rehabilitation in stroke survivors: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the effects of combined repetitive transcranial magnetic stimulation (rTMS) and mirror therapy (MT) on upper limb rehabilitation in stroke survivors.
Time toxicity in cancer care: a systematic review of definitions and measurement methods.
This systematic review examined the definitions and measurement methods of time toxicity in cancer care, involving 56 studies primarily from high-income countries.
Oral glucose solution for the treatment of persistent asymptomatic neonatal hypoglycemia: a randomized, double-blind, placebo-controlled trial.
This multicenter, randomized, double-blind, placebo-controlled trial evaluated the efficacy of buccal 50% dextrose solution (D50W) in treating persistent asymptomatic hypoglycemia in at-risk late preterm and term…
Recurrent serotonin syndrome during low-dose venlafaxine treatment in a patient with reduced CYP2D6 activity.
A man in his late 70s with transthyretin amyloidosis experienced recurrent serotonin syndrome while on low-dose venlafaxine treatment.
Refractory Acquired Thrombotic Thrombocytopenic Purpura in the Third Trimester of Twin Pregnancy: A Case Report.
A 29-year-old woman in her third trimester of a twin pregnancy presented with symptoms including palpitations, dyspnea, and oral bleeding, alongside severe thrombocytopenia.
The Effect of Emotional Freedom Techniques on Death Anxiety and Cancer-Related Anxiety in Patients Undergoing Oncological Surgery: A Randomized Controlled Trial.
This randomized controlled trial examined the impact of emotional freedom techniques (EFT) on death anxiety and cancer-related anxiety in 120 patients undergoing oncological surgery.
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