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2000 articles

October 202624

Case ReportPathology (Anatomic & Clinical)

Hodgkin Lymphoma With Sarcoid-Like Reaction: Importance of Clinicopathological Correlation in Granulomatous Lymphadenopathy.

A 63-year-old man with systemic lymphadenopathy had a cervical lymph node biopsy showing epithelioid granulomas but no identifiable neoplastic cells, prompting an initial suspicion of sarcoidosis.

Am J Case RepOct 12, 2026Read case
Clinical ResearchEndocrinology

Effectiveness of a self-management intervention on clinical outcomes among patients with type 2 diabetes at high risk for Diabetic Kidney Disease: A Randomised Controlled Trial.

This prospective, two-arm randomised controlled trial at a tertiary hospital in China evaluated a structured self-management programme in 134 adults with type 2 diabetes classified as at high risk of diabetic kidney…

PLoS OneOct 12, 2026Read summary
Clinical ResearchOncology (Medical)

Continuous intrathecal therapy for refractory cancer pain: A systematic review and meta-analysis focusing on partially implanted devices.

This systematic review and meta-analysis assessed partially implanted intrathecal devices (PIDs) for adults with refractory cancer-related pain, comparing them with conventional medical management and, in comparative…

Acta OncolOct 12, 2026Read summary
Case ReportPathology (Anatomic & Clinical)Open access

A case of immunofluorescence-negative light chain deposition disease diagnosed by mass spectrometry.

A 53-year-old man with kidney dysfunction and edema had nodular glomerular lesions on biopsy, but immunofluorescence did not show immunoglobulin or light-chain deposits.

CEN Case RepOct 12, 2026Read case
Clinical ResearchCardiology

Impact of Extent of Coronary Artery Disease in Transcatheter Aortic Valve Replacement: A PRO-TAVI Substudy.

This post hoc substudy of the multicentre randomised PRO-TAVI trial examined whether coronary disease complexity, measured by SYNTAX score, was associated with outcomes among 466 patients with significant coronary…

JACC Cardiovasc IntervOct 12, 2026Read summary
Clinical ResearchCardiology

Immediate Versus Staged Complete Revascularization in Multivessel Disease and STEMI: A Meta-Analysis of Randomized Trials.

This frequentist meta-analysis of four multicentre randomised trials compared immediate with staged complete revascularization in 2,651 patients with STEMI and multivessel disease.

JACC Cardiovasc IntervOct 12, 2026Read summary
Clinical ResearchCardiology

Occlusion-Focused Triage vs Very-High-Risk NSTEMI Criteria: A DIFOCCULT-3 Substudy.

This substudy of the multicenter, cluster-randomized DIFOCCULT-3 trial compared occlusion/nonocclusion (OMI/NOMI) classification with the conventional STEMI/NSTEMI framework and guideline-defined very-high-risk NSTEMI…

JACC Cardiovasc IntervOct 12, 2026Read summary
Clinical ResearchPlastic SurgeryOpen access

Anatomical variation in the cervical branch of the facial nerve: a systematic review.

There is a paucity of literature on the anatomical variations of the cervical branch of the facial nerve (CBFN). Poor awareness of its anatomy and variations risks intraoperative damage, misdiagnosis of facial nerve…

Surg Radiol AnatOct 12, 2026Read summary
Clinical ResearchInfectious Diseases

Predictors of immunological non-response despite virological suppression in people living with HIV on antiretroviral therapy: A systematic review and meta-analysis.

This systematic review and meta-analysis examined clinical, demographic and molecular predictors of inadequate CD4+ T-cell recovery despite viral suppression on antiretroviral therapy in people living with HIV.

PLoS OneOct 12, 2026Read summary
Clinical ResearchPulmonologyOpen access

Improvement in peripheral airway function after a 12-week exercise intervention in COPD.

This prospective, multicenter, single-arm non-randomized intervention study assessed lung function, exercise capacity and symptoms before and after a 12-week supervised exercise program in 62 people with COPD.

Respir ResOct 12, 2026Read summary
Clinical ResearchAnesthesiologyOpen access

Analgesic efficacy of uni-level erector spinae plane block in breast cancer surgery patients: a systematic review and Meta-analysis.

This systematic review and meta-analysis assessed uni-level erector spinae plane block (ESPB) as an adjunct to general anesthesia and opioids for breast cancer surgery.

BMC AnesthesiolOct 12, 2026Read summary
Case ReportPediatricsOpen access

Robotic Parenchyma-Preserving Pancreatic Resection for Focal Congenital Hyperinsulinism in an Infant.

An infant weighing 4.6 kg with focal congenital hyperinsulinism underwent robot-assisted, parenchyma-preserving pancreatic resection using indocyanine green, intraoperative ultrasound, and suture-based retraction.

CRSLSOct 12, 2026Read case
Clinical ResearchOphthalmologyOpen access

Oral eplerenone in first-episode acute central serous chorioretinopathy: results of a double-masked randomized trial.

This double-masked, randomized, placebo-controlled trial evaluated oral eplerenone in 44 patients with first-episode acute central serous chorioretinopathy (CSCR).

Int OphthalmolOct 12, 2026Read summary
Clinical ResearchDermatology

Comparative efficacy of topical garlic extract and 20% podophyllin solution in the treatment of female genital warts: a triple-blind randomized clinical trial.

This triple-blind randomized clinical trial compared topical 5% garlic extract with 20% podophyllin in 74 women with genital warts, applied weekly for four weeks.

J Dermatolog TreatOct 12, 2026Read summary
Clinical ResearchObstetrics & GynecologyOpen access

Progestogens, cervical cerclage, and cervical pessary for preventing preterm birth in asymptomatic singleton pregnancies with a sonographic short cervix and no previous history of spontaneous preterm birth: systematic review and bayesian network meta-analysis.

This systematic review and Bayesian network meta-analysis compared interventions to prevent preterm birth in asymptomatic women with singleton pregnancies, a sonographic short cervix, and no previous spontaneous preterm…

BMJ MedOct 12, 2026Read summary
Clinical ResearchPulmonology

Effectiveness of a fully digital mandibular advancement appliance compared with CPAP in the treatment of obstructive sleep apnea.

This crossover clinical study compared a fully digital mandibular advancement appliance (MAA) with CPAP in 20 adults with obstructive sleep apnea (OSA), confirmed by polysomnography and non-adherent to CPAP.

Dental Press J OrthodOct 12, 2026Read summary
Case ReportInfectious Diseases

Brought with the wind: A case of melioidosis acquired in the United States presenting with multiple pulmonary nodules.

A Florida resident without recent international travel presented with fever, pleuritic chest pain, and hypoxia after severe weather.

PLoS Negl Trop DisOct 12, 2026Read case
Case ReportNeurology

The Effects of Multimodal Communication Treatment With Discourse and Group Activities via Telepractice on People With Severe Nonfluent Aphasia: A Case Study.

Two people with severe nonfluent aphasia—one with Broca’s aphasia and one with global aphasia—received 10 weeks of telepractice multimodal communication treatment.

Am J Speech Lang PatholOct 12, 2026Read case
Clinical ResearchRheumatology

Osteopathic manual therapy in fibromyalgia: a pilot study.

This pilot randomised controlled trial assessed whether adding osteopathic manual therapy to Clinical Pilates improved pain, symptom severity, pressure pain threshold, and sleep in 20 women with fibromyalgia.

Rev Assoc Med Bras (1992)Oct 12, 2026Read summary
Case ReportPediatrics

Use of Instructional Therapeutic Play during the preoperative nursing consultation of a child with orofacial clefts.

An 8-year-old girl with an orofacial cleft was preparing for cleft palate repair and expressed fear and anxiety about surgery, especially that she might not wake up after anesthesia.

Rev Esc Enferm USPOct 12, 2026Read case
Clinical ResearchGeneral SurgeryOpen access

The effectiveness of guided botulinum toxin "A" injection to the masticatory muscles in the management of condylar and sub condylar fractures: a randomized controlled clinical trial.

This randomized controlled clinical trial compared ultrasound-guided botulinum toxin A injections into the masseter, temporalis and lateral pterygoid muscles plus closed reduction with closed reduction alone in 16…

BMC Oral HealthOct 12, 2026Read summary
Clinical ResearchCardiologyOpen access

Robotic-assisted versus conventional coronary artery bypass grafting: a systematic review, meta-analysis, and trial sequential analysis of 39,918 patients.

This systematic review and meta-analysis compared robotic-assisted with conventional coronary artery bypass grafting (CABG) across nine observational studies involving 39,918 patients.

J Cardiothorac SurgOct 12, 2026Read summary
Clinical ResearchPsychiatry

Assessment of Autism Spectrum Disorder in Gender-Diverse Populations: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis examined how autism spectrum disorder (ASD) and autistic traits are assessed in gender-diverse populations.

LGBT HealthOct 12, 2026Read summary
Clinical ResearchEmergency MedicineOpen access

The impact of kinesiotaping on functional respiratory outcome in chest injuries-a pilot randomized trial.

This pilot randomized trial compared kinesiotaping (KT) plus breathing exercises with breathing exercises alone in 34 patients with isolated unilateral injuries involving fewer than five ribs.

PeerJOct 12, 2026Read summary

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