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2000 articles
October 202624
Probable vestibular paroxysmia mimicking benign paroxysmal positional vertigo of the superior semicircular canal in the presence of a neurovascular conflict: a case report and review of the literature.
A 52-year-old woman presented with positional vertigo and was initially diagnosed with right superior semicircular canal benign paroxysmal positional vertigo (BPPV).
Prospective controlled study of the recombinant zoster vaccine in autoimmune rheumatic disease: robust seroconversion despite intravenous cyclophosphamide.
This subanalysis of a prospective, randomized, placebo-controlled trial assessed recombinant zoster vaccine (RZV) responses in patients with autoimmune rheumatic disease receiving intravenous cyclophosphamide (IVCYC)…
Prediction models for postpartum post-traumatic stress disorder: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed multivariable models predicting post-traumatic stress disorder within 12 months after childbirth.
Challenging historical associations and reassuring women: an updated meta-analysis of multiple sclerosis relapse risk following assisted reproductive technology.
This systematic review and random-effects meta-analysis examined whether assisted reproductive technology (ART) is associated with multiple sclerosis (MS) relapses in women with MS or incident MS in previously healthy…
Safety and Immunogenicity of the Live-Attenuated Quadrivalent Dengue Vaccine V181 Compared With Butantan-DV Among Healthy Adults in Brazil: A Randomized, Double-Blind, Phase 2 Trial.
This randomized, double-blind, active-comparator phase 2 trial compared the safety and immunogenicity of single-dose quadrivalent dengue vaccines V181 and Butantan-DV in healthy adults in Brazil.
Fosfomycin as Oral Transition Therapy Versus Continued Intravenous β-Lactams for Complicated Urinary Tract Infections Caused by Extended-Spectrum β-Lactamase-Producing Enterobacterales: A Multicenter, Open-Label, Randomized Controlled Trial.
This multicenter, open-label randomized noninferiority trial compared oral fosfomycin transition therapy with continued intravenous carbapenem or β-lactam/β-lactamase inhibitor therapy in hospitalized adults with…
Effect of a Single Subanesthetic Dose of Esketamine on Gastrointestinal Recovery After Laparoscopic Colorectal Cancer Surgery: A Randomized, Outcome-Assessor-Blinded, Placebo-Controlled Trial.
Postoperative gastrointestinal dysfunction (POGD) and Postoperative gastrointestinal intolerance (POGI) remain a critical challenge in abdominal surgery, particularly for colorectal cancer patients undergoing…
Successful treatment of hairy cell leukemia with TP53 abnormality using cladribine combined with low-dose rituximab: a case report and literature review.
An elderly man with classical hairy cell leukemia (HCL) had BRAF V600E positivity, a TP53 deletion detected by fluorescence in situ hybridization, and bone marrow fibrosis.
Anxiety and Depression in Athletes of Different Levels Without Current Injury: A Systematic Review With Meta-Analyses.
This systematic review and random-effects meta-analysis examined anxiety and depression in athletes across competitive levels, including those without current injury.
Multiple Sclerosis During Pregnancy and the Postpartum Period: Diagnostic and Multidisciplinary Challenges in Two Cases.
The report describes two pregnant women with progressive focal neurological symptoms and brain MRI abnormalities concerning for central nervous system demyelination.
Dose response relationship of medical cannabis and symptom control in patients with pancreatic cancer: an analysis of the CANPAN trial.
This analysis of the CANPAN pilot waitlist-control randomized trial examined cannabis use, patient-reported outcome completion, and THC dose-response among 32 cannabis-naïve patients with newly diagnosed locally…
Acrokeratosis paraneoplastica (Bazex syndrome): a systematic review and quantitative analysis of 106 cases.
Acrokeratosis paraneoplastica (Bazex syndrome) is an obligate paraneoplastic dermatosis characterized by symmetrical acral psoriasiform lesions and nail dystrophy.
Chemotherapy backbone and outcomes of immune checkpoint inhibitor combinations across solid tumors: a pan-tumor network meta-analysis.
This systematic review and network meta-analysis examined phase II–III randomised trials comparing first-line immune checkpoint inhibitor (ICI) plus chemotherapy with chemotherapy alone across solid tumours, assessing…
Safety, Efficacy, and Immunogenicity of a Multivalent Adjuvanted Staphylococcus aureus Vaccine in Adults With Recent Skin and Soft Tissue Infections: An Observer-Blind, Randomized, Placebo-Controlled, Multinational Phase 1/2 Trial.
This observer-blind, randomized, placebo-controlled phase 1/2 trial evaluated a five-antigen Staphylococcus aureus vaccine with AS01E adjuvant in adults, including 194 participants aged 18–64 years with a recent S.
Sunitinib in Patients With Various Solid Tumors With FGFR1 / 2 Alterations: Results From the Targeted Agent and Profiling Utilization Registry (TAPUR) Study.
This phase II basket trial evaluated sunitinib in patients with advanced solid tumours and FGFR1 or FGFR2 alterations who had no remaining standard treatment options. Histology-specific cohorts were pooled by alteration.
Managing 7-Hydroxymitragynine Use Disorder with Buprenorphine-Naloxone.
A patient who had used kratom to stop illicit opioids developed tolerance and transitioned to 7-hydroxymitragynine, believing the plant-derived product was safe.
Efficacy of direct-acting antiviral regimens for acute HCV infection: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed interferon-free dual direct-acting antiviral regimens for acute or recently acquired HCV infection.
Systematic Review and Meta-Analyses of Time-Use, Productivity, and Labor Outcomes Among Unpaid Cancer Caregivers.
This systematic review and meta-analysis pooled evidence on time use and labor outcomes among unpaid caregivers of adults with cancer.
Daily sedation interruption versus no daily sedation interruption for critically ill adults and children requiring invasive mechanical ventilation.
This updated Cochrane systematic review and meta-analysis assessed daily sedation interruption (DSI) versus sedation strategies without interruption in critically ill adults and children receiving invasive mechanical…
The efficacy of surgical interventions for trigeminal neuralgia in multiple sclerosis: A systematic review.
This systematic review with narrative synthesis assessed surgical treatments for trigeminal neuralgia in people with multiple sclerosis, using studies reporting Barrow Neurological Institute Pain Scale outcomes.
Multidimensional Poverty and Implementation Reach of Household Contact Tracing for Tuberculosis in South Africa: Analysis of a Randomized Trial.
This analysis of a cluster-randomized trial in South Africa examined whether household multidimensional poverty was associated with the reach of household contact tracing (HHCT) for tuberculosis.
Recurrent Ovarian Torsion Despite Previous Oophoropexy in a 9-Year-Old Prepubertal Girl: A Pediatric Emergency Department Perspective.
A 9-year-old prepubertal girl with prior left ovarian torsion treated by laparoscopic detorsion and oophoropexy presented with severe intermittent left-sided abdominal pain and vomiting.
Costs and health-related quality of life of non-operative and surgical treatment modalities for displaced distal radius fractures: a comprehensive overview based on the CAST study.
This cost and health-related quality-of-life analysis used data from the multicenter cluster-randomized CAST trial of adults with displaced distal radius fractures.
Parkinsonism with Reduced Striatal Uptake on DAT-SPECT in a Patient Harboring a Novel KCND3 Variant.
A Japanese patient with a novel KCND3 missense variant classified as a variant of uncertain significance had childhood-onset, slowly progressive cerebellar ataxia and asymmetric parkinsonism, a phenotype compatible with…
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