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2000 articles
October 202624
A Phase 1/2 Dose-Ranging Safety and Immunogenicity Study of mRNA-Based Candidate Pandemic Influenza Vaccines in Healthy Adults.
This randomised phase 1/2 dose-ranging study evaluated the safety, reactogenicity, and immunogenicity of mRNA-1018 pandemic influenza vaccine candidates in healthy adults.
Janus kinase inhibitors in the management of lichen planus: a systematic review.
Lichen planus (LP) is a chronic, lymphocytic, inflammatory skin disorder that can affect the skin, hair follicles, nails, and mucous membranes. It has limited treatment options.
MRI-derived radiomics for prostate cancer active surveillance: a systematic review.
This PRISMA 2020 systematic review assessed MRI-derived radiomic and artificial intelligence models for selecting men with prostate cancer for active surveillance, detecting clinically significant cancer at baseline…
Three Months of Weekly Rifapentine and Isoniazid Versus Four Months of Daily Rifampicin for Tuberculosis Infection: A Randomized Controlled Trial.
This multicenter, open-label randomized controlled trial compared treatment completion with weekly isoniazid plus rifapentine for 3 months (3HP) versus daily rifampicin for 4 months (4RIF) among people of any age with…
Approach to management of walled-off necrosis secondary to trauma-induced pancreatitis in a limited-resource setting.
A patient with trauma-induced pancreatitis developed a walled-off necrosis (WON) characterized by a necrotic peripancreatic collection. Imaging revealed a mature collection with necrotic debris.
Artificial intelligence-powered renal pathology for glomerular disease classification: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the performance of artificial intelligence (AI) models in classifying glomerular diseases using pathology images.
'Life has become a lot easier'-the acceptability of the treatable traits clinic experience to people with bronchiectasis.
This exploratory qualitative study examined how adults with bronchiectasis experienced a regional Australian outpatient clinic using a treatable-traits approach.
Acute effects of volume-matched isometric exercise intensity on vascular function and autonomic regulation in men with elevated blood pressure.
This randomized controlled trial examined the acute effects of high-intensity isometric exercise (HIIE) versus low-intensity isometric exercise (LIIE) on cardiovascular function in 17 men with elevated blood pressure.
Efficacy and safety of roxadustat for the treatment of renal anemia in patients undergoing peritoneal dialysis: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the efficacy and safety of roxadustat for treating renal anemia in patients undergoing peritoneal dialysis.
Infection burden in mismatched unrelated donor hematopoietic cell transplantation: results from the ACCESS trial.
The ACCESS trial evaluated infection burden in 268 adult patients undergoing HLA-mismatched unrelated donor hematopoietic cell transplantation (HCT) with posttransplant cyclophosphamide (PTCy) for graft-versus-host…
Rupture of Left Ventricular Aneurysm in Infant: Case Report.
A preterm infant hospitalized from birth with necrotizing enterocolitis, later complicated by ascending-colon narrowing requiring surgery, had persistent infections with Staphylococcus haemolyticus and then…
Neuromuscular, Balance, and Gait Factors Associated with Falls and Fall-Related Outcomes in Individuals with COPD: A Systematic Review.
This systematic review examined associations between muscle strength, balance, gait and falls or fall-related outcomes in people with COPD. It included 25 original studies involving 1295 participants.
Severe Euglycemic Diabetic Ketoacidosis After Semaglutide-Associated Poor Intake Despite Empagliflozin Discontinuation: A Case Report.
A 68-year-old woman with long-standing type 2 diabetes developed several weeks of nausea, intermittent vomiting and diarrhea, and minimal oral intake after starting semaglutide.
Exercise to enhance antipsychotic effectiveness and mitigate metabolic harm: systematic review and meta-analysis.
This systematic review and meta-analysis pooled randomised controlled trials of supervised exercise in adults receiving antipsychotic medication for psychotic disorders.
Brief social contact videos to promote treatment seeking among young adults with depressive symptoms: Intention change, suicidal ideation, and treatment use in a randomized controlled trial.
This randomized controlled trial tested whether brief social contact videos featuring personal recovery stories increased help-seeking and treatment use among 1,545 young adults aged 18–25 years with depressive…
Standardized Acupuncture Plus Modified Xiaoxuming Decoction for Acute Ischemic Stroke: A Randomized Controlled Trial.
This single-center, assessor-blinded randomized controlled trial enrolled adults with imaging-confirmed acute ischemic stroke within 72 hours and compared standard care with or without standardized acupuncture plus…
Cannabis use and subsequent onset of manic symptoms and bipolar disorder: A systematic review and meta-analysis.
This registered systematic review and meta-analysis examined longitudinal observational studies of people without prior bipolar disorder, comparing those exposed and unexposed to cannabis.
Maternal circulating cytokine and chemokine levels during pregnancy and risk of autism spectrum disorder in offspring: A systematic review and meta-analysis.
This systematic review and meta-analysis examined whether maternal blood cytokine and chemokine levels during pregnancy were associated with autism in offspring, drawing on seven human observational studies.
Febrile neutropenia in adults with diffuse large B-cell lymphoma receiving first-line R-CHOP-based therapy: a systematic review and meta-analysis of observational and trial evidence.
This systematic review and meta-analysis assessed febrile neutropenia (FN) in adults with diffuse large B-cell lymphoma receiving first-line R-CHOP or R-CHOP-like therapy, separating observational cohorts from clinical…
Physical activity for psychological and physical well-being in menstruating individuals: an integrative review.
This integrative review synthesised qualitative, quantitative, and mixed-methods research on physical activity and psychological or physical well-being across the menstrual cycle.
Changes in health literacy following participation in a multidisciplinary primary care intervention for people with chronic pain: a longitudinal cohort study.
This longitudinal cohort study examined changes in health literacy among 43 people with chronic non-cancer pain who completed a personalized, multidisciplinary primary care pain-management intervention.
The Effect of a Very Low-Carbohydrate Diet on Intermuscular Adipose Tissue and Muscle Function in Older Adults With Obesity.
This randomized controlled trial compared a weight-maintaining very low-carbohydrate diet (VLCD) with a low-fat diet (LFD) over 8 weeks in adults aged 60 years or older with obesity.
Safe electrophysiology-guided resection of an epileptogenic non-exophytic hamartoma at the floor of the fourth ventricle in a child.
Hamartoma of the floor of fourth ventricle (HFFV) is an extremely rare entity known to be causing focal movement disorders in children.
Iron or Multiple Micronutrient Powder Supplements With Malaria Chemoprevention in Rural Malawian Children: The IRMA Randomized Clinical Trial.
This randomized clinical trial evaluated the effects of iron supplements combined with malaria chemoprevention on cognitive outcomes in 6-month-old infants in rural Malawi.
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