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1998 articles
October 202624
Protective effect of N-acetylcysteine on oxaliplatin-induced peripheral neuropathy in colorectal cancer: a randomized controlled trial.
This randomized controlled trial evaluated oral N-acetylcysteine (NAC) for preventing oxaliplatin-induced peripheral neuropathy in 46 patients with stage III or high-risk stage II colorectal cancer receiving adjuvant…
Streptococcus constellatus-Associated Lemierre Syndrome Presenting With Cavitating Septic Pulmonary Emboli Managed by Video-Assisted Thoracoscopy.
A previously healthy 25-year-old man presented with a week of dyspnea, productive cough, fever, and hemoptysis, with severe hypoxemia and respiratory distress.
The entorhinal cortex atrophy score for diagnostic distinction between phases of the Alzheimer's disease continuum.
This systematic review assessed the Entorhinal Cortex Atrophy (ERICA) visual score for distinguishing subjective cognitive decline (SCD), mild cognitive impairment (MCI), and Alzheimer’s disease (AD) dementia.
Fractional CO₂ laser combined with intradermal and topical platelet-rich plasma for hypertrophic scars: a randomized controlled trial.
This prospective, randomized, assessor-blinded trial compared fractional CO₂ laser plus intradermal and topical platelet-rich plasma (PRP) with laser plus saline in 120 patients with hypertrophic scars.
Feasibility of a Co-Designed Personalized Cognitive Reablement Program Delivered via Digital Voice Assistants for Older Adults Living With Early-Stage Dementia or Mild Cognitive Impairment: Pilot Randomized Controlled Trial.
This nonblinded pilot randomized controlled trial assessed the feasibility and potential effectiveness of VOICE-COG, a personalized cognitive reablement program delivered through digital voice assistants, in adults aged…
Precancerous cervical lesions and associated factors among HIV-positive women in Southern and Eastern African countries: A systematic review and meta-analysis.
This systematic review and meta-analysis pooled evidence on precancerous cervical lesions (PCCL) and associated factors among women living with HIV in Southern and Eastern Africa.
Effects of E-Coach-Based Chronic Disease Management on Self-Management, Quality of Life, and Mental Health in Maintenance Hemodialysis Patients.
This randomized controlled trial evaluated a WeChat-based E-Coach programme in 96 patients receiving maintenance hemodialysis, comparing usual care plus E-Coach with usual care alone.
The Impact of Telemedicine Interventions on Maternal and Fetal Outcomes in Women With Gestational Diabetes: Systematic Review and Meta-Analysis of Randomized Controlled Trials.
This systematic review and meta-analysis pooled 23 randomized controlled trials involving 3055 women with gestational diabetes to assess telemedicine and maternal and fetal outcomes.
Extracorporeal photopheresis for the treatment of steroid-refractory immune related adverse events from immune checkpoint inhibitor therapy: a multi-center phase Ib/II clinical trial.
This prospective, single-arm, non-randomized phase Ib/II multicentre trial evaluated extracorporeal photopheresis (ECP) for steroid-refractory immune-related adverse events (irAEs) in 30 patients receiving immune…
Prophylactic neurectomy versus nerve preservation in open inguinal hernia repair for prevention of chronic postoperative inguinal pain (CPIP): a systematic review and meta-analysis.
This systematic review and meta-analysis assessed prophylactic neurectomy versus nerve preservation in adults undergoing elective open anterior inguinal hernia repair, including 17 randomized trials.
Immediate vs delayed extubation after pediatric liver transplantation: a systematic review and meta-analysis.
This systematic review and meta-analysis compared immediate operating-room extubation with delayed extubation after pediatric orthotopic liver transplantation.
Robot-Assisted Radical Prostatectomy in a Post-Enucleation Gland.
A 64-year-old man was found to have right-lobe ISUP grade 3 prostate adenocarcinoma after HoLEP for benign prostatic obstruction. PSA was 0.51 ng/mL, and MRI showed a 0.4 cm PI-RADS 4 lesion.
Anatomopathological Aspects and Clinical Correlation of Conjunctival Bleb Fibrosis Following Encapsulation of a Biodegradable Collagen Matrix Implant in Glaucoma Surgery.
Four patients with progressive glaucoma and inadequate intraocular pressure control despite maximal medical therapy underwent non-penetrating deep sclerectomy with a biodegradable collagen-glycosaminoglycan implant and…
Intermittent Maple Syrup Urine Disease Presenting With Chronic Demyelinating Polyneuropathy: A Genetically Confirmed DBT-Related Case.
A female patient with intermittent maple syrup urine disease (MSUD), genetically confirmed by compound heterozygous pathogenic DBT variants, had recurrent ataxic episodes from early childhood.
A Methodological Framework for a Large Language Model Virtual Companion for Older Adults at Risk of Social Isolation.
This paper presents a methodological framework for developing and evaluating a large language model (LLM)-driven virtual companion for older adults at risk of social isolation.
The perceptions of hematopoietic stem cell transplantation decision-making in patients with hematologic malignancies: a qualitative systematic review.
This qualitative systematic review synthesized research on how patients with hematologic malignancies perceive decisions about hematopoietic stem cell transplantation (HSCT).
Spontaneous regression of post-traumatic syringomyelia: longitudinal mr imaging demonstrating a dynamic disease course.
A 69-year-old patient with post-traumatic cervicothoracic syringomyelia presented with occipital headaches, dizziness, and subjective upper-extremity weakness.
Association between cancer cachexia and treatment-related adverse outcomes in patients with gastrointestinal cancers: a systematic review and meta-analysis.
This systematic review and meta-analysis examined cohort studies of cancer cachexia and treatment-related outcomes in patients with gastrointestinal cancers.
Successful treatment with BrECADD in a patient with Dubin-Johnson syndrome and classic Hodgkin lymphoma: a case report.
A 26-year-old man with advanced-stage classic Hodgkin lymphoma also had Dubin–Johnson syndrome (DJS) associated with a homozygous ABCC2 variant, c.2291G>A (p.Gly764Asp).
Extending the Graft Harvesting Area in Severe Penoscrotal Hypospadias: The Rainbow Technique.
A 2-year-old with severe penoscrotal hypospadias, a scrotal meatus, bifid scrotum, and chordee exceeding 90° underwent first-stage reconstruction.
Hematological and biochemical responses to three doses of caffeine during the CrossFit® workout: a randomized, double-blind, crossover trial.
This randomized, double-blind, placebo-controlled crossover trial examined hematological and biochemical responses to caffeine during a 17-minute CrossFit® workout in 26 moderately trained athletes.
Skeletal effects of GLP-1 receptor agonist therapy in adults with overweight or obesity: a systematic review.
This systematic review examined randomized evidence on bone mineral density (BMD) and bone-turnover markers in adults with overweight or obesity receiving GLP-1 receptor agonists.
Lesion Water Content on CT Predicts 12-Month Outcome and Modifies Thrombectomy Effect in Large-Core Stroke-A Secondary Analysis of the TENSION Trial.
This secondary analysis of the randomized TENSION trial examined whether CT-derived net water uptake (NWU) predicts 12-month outcomes and modifies thrombectomy effects in 198 patients with large-core ischemic stroke.
STN-SNr co-stimulation in Parkinson's disease: a systematic review and meta-analysis of motor and freezing-of-gait outcomes.
This systematic review and meta-analysis assessed whether adding substantia nigra pars reticulata stimulation to subthalamic nucleus deep brain stimulation improves motor function or freezing of gait in people with…
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