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2000 articles
October 20268
Ultrasound-Guided Dorsal Penile Nerve Block Reduces Perioperative Opioid Requirements in Pediatric Circumcision: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the effectiveness of ultrasound-guided versus landmark-based dorsal penile nerve block (DPNB) in reducing opioid requirements during pediatric circumcision.
Updated Meta-Analysis of Left Atrial Appendage Closure Versus Oral Anticoagulation to Prevent Stroke in Atrial Fibrillation.
This systematic review and meta-analysis pooled six randomized controlled trials comparing percutaneous left atrial appendage closure (LAAC) with oral anticoagulation in 7028 patients with nonvalvular atrial…
A hypertensive response to irrigation: endoscopic repair of a ventral spinal CSF leak.
A 36-year-old woman with recurrent spontaneous intracranial hypotension due to a ventral T11-12 CSF leak underwent endoscopic repair.
Digital Health Technologies for Risk Factor Management and Secondary Prevention After Stroke: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the effectiveness of digital health interventions for managing vascular risk factors in stroke survivors.
DDX3Y loss-of-function variant in AZFa-like non-obstructive azoospermia highlights gaps in current Y-chromosome microdeletion testing.
A man with idiopathic non-obstructive azoospermia presented with an AZFa-like phenotype, characterized by elevated FSH and a normal karyotype.
Systematic Review: Inclusion of Patients With Difficult-to-Treat Inflammatory Bowel Disease in Randomized Controlled Trials of Advanced Therapies.
This systematic review examined how patients with difficult-to-treat inflammatory bowel disease (DTT-IBD) were represented in randomized controlled trials of advanced therapies for ulcerative colitis and Crohn’s…
Quetiapine modestly improves sleep and breathing but impairs next-day performance in people with obstructive sleep apnea and difficulty maintaining sleep: a randomized controlled trial.
This randomized controlled trial evaluated the effects of 50 mg quetiapine versus placebo in 15 individuals with obstructive sleep apnea (OSA) and difficulty maintaining sleep.
Opioid Use and Family Members' Experiences of Opioids in Paediatric Cancer Pain Management: An Integrative Review.
This integrative review analyzed opioid use in pediatric cancer pain management and family members' experiences. Sixteen peer-reviewed articles were reviewed, revealing that morphine and fentanyl are the most commonly…
September 202616
Impact of EBV status and histology on patient outcomes with nivolumab-AVD vs BV-AVD in advanced classic Hodgkin lymphoma (S1826).
This phase 3 randomized controlled trial evaluated the impact of EBV status and histology on outcomes in patients with advanced classic Hodgkin lymphoma treated with nivolumab-AVD (N-AVD) versus brentuximab vedotin-AVD…
Pyogenic Granuloma in the Sinonasal Cavity: A Potential 38-Year Latency Following Foreign Body Entrapment.
A 43-year-old male presented with left-sided nasal obstruction, rhinorrhea, and hyposmia for two months. Endoscopic evaluation and imaging revealed a highly vascular mass on the left middle turbinate.
A phase 1b/2 study of ceralasertib, a selective inhibitor of ATR, in patients with relapsed or refractory MDS and CMML.
This phase 1b/2 study evaluated ceralasertib, an ATR inhibitor, in 44 adults with relapsed or refractory MDS and CMML. The overall response rate was 29.5%, with a median progression-free survival of 4.8 months and…
Dexketoprofen Trometamol Plus Sufentanil for Analgesia After Thoracoscopic Radical Resection of Lung Cancer: A Randomized, Double-Blind, Placebo-Controlled Trial.
Evidence for adding dexketoprofen trometamol to sufentanil-based patient-controlled intravenous analgesia (PCIA) after thoracoscopic radical resection of lung cancer remains limited.
Tegileridine versus Sufentanil for Patient-Controlled Intravenous Analgesia After Cesarean Delivery: A Randomized Double-Blind Trial.
Postoperative nausea and vomiting (PONV) remains one of the most common opioid-related adverse events after cesarean delivery despite multimodal analgesia.
Thalamic Tuberculoma Presenting as Isolated Gait Disturbance Without Systemic or Meningeal Symptoms in a 2-Year-Old Child: A Case Report.
A 2-year-old boy presented with isolated gait disturbance and decreased power on the left side, without systemic or meningeal symptoms.
Saprochaete pneumonia presenting as septic shock in an elderly patient with poorly controlled diabetes mellitus.
An elderly woman with poorly controlled diabetes presented with community-acquired pneumonia, septic shock, and multi-organ dysfunction. Despite initial antibiotic treatment, her condition deteriorated.
A phase 1/1b study of the all-oral regimen CC-486 and venetoclax in acute myeloid leukemia.
This phase 1/1b study evaluated the all-oral regimen of CC-486 and venetoclax in patients with relapsed, refractory, and newly diagnosed acute myeloid leukemia (AML).
A specialist-led interprofessional weaning program to prevent weaning failure in high-risk patients: the PRiVENT study.
The PRiVENT study evaluated a specialist-led interprofessional weaning program for high-risk mechanically ventilated patients in a multicenter, non-randomized trial.
Implementation of Total Body Photography for Skin Cancer Early Detection: A Systematic Review.
This systematic review examined how total body photography (TBP) has been implemented and used for skin cancer detection and surveillance across healthcare settings.
Metastatic muscle invasive bladder cancer in pregnancy.
A woman in her 30s presented during the second trimester with hematuria and left flank pain. MRI identified a T3b bladder tumor with suspected peritoneal invasion.
'Once Bitten': A Case of Tetanus Following Snakebite in Australia.
A 58-year-old woman in Victoria, Australia, presented after a suspected Tiger snake bite. She was not current with her tetanus vaccination and did not receive a booster.
Anakinra versus intramuscular methylprednisolone acetate for gout flares in people with chronic kidney disease (ASGARD): a UK randomised multicentre, double-blind, double-dummy controlled feasibility study with economic, qualitative and safety assessment.
The ASGARD study was a feasibility randomized controlled trial comparing anakinra to intramuscular methylprednisolone acetate for treating gout flares in patients with chronic kidney disease.
Intracardiac vs. transesophageal echocardiography in patients undergoing ablation for atrial fibrillation: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the safety and efficacy of intracardiac echocardiography (ICE) versus transesophageal echocardiography (TEE) in 7671 patients undergoing catheter ablation for atrial…
A meta-analysis of transjugular intrahepatic portosystemic shunt with or without embolization for esophageal and gastric variceal bleeding in decompensated liver cirrhosis.
This meta-analysis evaluated the efficacy of transjugular intrahepatic portosystemic shunt (TIPS) with or without embolization in 3079 patients with decompensated liver cirrhosis experiencing esophageal and gastric…
Percutaneous catheter drainage versus needle aspiration for liver abscess: a systematic review and meta-analysis of efficacy and safety.
This systematic review and meta-analysis evaluated the efficacy and safety of percutaneous catheter drainage (PCD) versus needle aspiration (PNA) for liver abscesses in 1425 adults.
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