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2000 articles
September 202624
Carfilzomib plus induction chemotherapy for children with relapsed or refractory acute lymphoblastic leukemia.
This phase II clinical trial evaluated the efficacy of carfilzomib combined with induction chemotherapy (CFZ-VXLD) in pediatric patients aged 1 month to <21 years with relapsed or refractory acute lymphoblastic leukemia…
Unravelling deregulated metabolites in seminal plasma of infertile men: a systematic review and bioinformatic analysis.
This systematic review analyzed metabolomic studies comparing seminal plasma metabolites in healthy and infertile men. It included 20 studies and identified 284 metabolites, with specific alterations linked to…
Comparative pain relief and functional outcomes following robotic-assisted versus conventional total knee arthroplasty: a GRADE-assessed meta-analysis with meta-regression of randomized controlled trials.
This meta-analysis of 24 randomized controlled trials involving 3,425 patients compared robotic-assisted total knee arthroplasty (RA-TKA) with conventional TKA (C-TKA).
Comparison of bivalirudin versus heparin in percutaneous coronary intervention for patients with acute coronary syndrome: A meta-analysis.
This meta-analysis compared bivalirudin and heparin in patients with acute coronary syndrome undergoing percutaneous coronary intervention, including 11 RCTs and 17 cohort studies with 584,249 patients.
Radiotherapy versus observation following surgical resection of WHO grade 2 atypical meningioma (ROAM/EORTC-1308): an international, multicentre, open-label, phase 3, randomised controlled trial.
ROAM/EORTC-1308 was an international, multicentre, open-label, phase 3 randomised trial comparing adjuvant radiotherapy with observation after complete resection of newly diagnosed WHO grade 2 atypical meningioma.
Vision loss as the first manifestation of isolated cns relapse in CML blast crisis during flumatinib maintenance therapy: A case report.
A 65-year-old male with chronic myeloid leukemia in complete remission presented with progressive vision loss, indicating isolated CNS relapse.
Predictors of Pulmonary Complications After Rib Fractures: Systematic Review and Meta-Analyses.
This systematic review and meta-analysis examined multivariable-adjusted predictors of pulmonary complications in adults with blunt rib fractures.
ATM mutations in myelodysplastic neoplasms, acute myeloid leukemia, and myeloproliferative neoplasms: a systematic review.
This systematic review evaluated the impact of ATM mutations in myelodysplastic neoplasms (MDS), acute myeloid leukemia (AML), and myeloproliferative neoplasms (MPN).
Left-sided 3D totally endoscopic mitral valve repair guided by left atrial appendage orientation in situs inversus totalis with mirror-image dextrocardia: a case report.
A 39-year-old woman with situs inversus totalis and mirror-image dextrocardia presented with progressive exertional dyspnea due to severe mitral regurgitation from posterior leaflet prolapse.
Lymphocutaneous sporotrichosis: A case report from southeastern China and review of the literature.
A 53-year-old male presented with multiple ulcerated lesions, leading to a diagnosis of lymphocutaneous sporotrichosis. Pathological analysis showed an inflammatory reaction, while imaging studies were normal.
Effectiveness of cognitive behavioral therapy for postpartum depression: a systematic review and meta‑analysis.
This systematic review and meta-analysis assessed cognitive behavioral therapy (CBT) for postpartum depression (PPD), comparing it with usual care in randomized controlled trials.
Iberdomide plus daratumumab and dexamethasone versus daratumumab, bortezomib, and dexamethasone in patients with relapsed or refractory multiple myeloma (EXCALIBER-RRMM): an open-label, randomised, controlled, phase 3 trial.
EXCALIBER-RRMM is an ongoing, open-label, randomised phase 3 trial comparing iberdomide, daratumumab, and dexamethasone with daratumumab, bortezomib, and dexamethasone in adults with relapsed or refractory multiple…
Wearable Sensors in Gait Assessment for Parkinson Disease and Stroke in Real-World Environments: Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the use of wearable sensors for gait assessment in patients with Parkinson disease (PD) and stroke. It included 43 studies, primarily focusing on PD (2774 participants).
The effect of dance movement therapy on traumatized refugee women - a clinical controlled trial.
This controlled clinical trial evaluated the effects of dance movement therapy (DMT) on 24 traumatized refugee women in Germany.
Sequential combination of anti-PD-1 antibody and PEG-IFNα in chronic hepatitis B patients: correlates of HBsAg loss with enhanced T-cell responses.
This pilot clinical trial investigated the sequential combination of anti-PD-1 antibody (sintilimab) and PEG-IFNα in ten virologically suppressed chronic hepatitis B patients.
Aggressive brainstem listeria abscess in an immunocompetent individual: A case report.
An immunocompetent patient in their late 50s presented with neurolisteriosis characterized by multifocal brainstem abscesses. The case involved an extensive negative infectious workup and a complex antibiotic regimen.
Blood pressure targets for hypertension in people with diabetes mellitus.
This Cochrane systematic review protocol aims to evaluate whether lower blood pressure targets (≤ 130/85 mmHg) reduce mortality and morbidity compared to standard targets (≤ 140 to 160/90 to 100 mmHg) in individuals…
Temporally Based Orbicularis Oculi Myocutaneous Flap for Pediatric Postexcisional Cicatricial Lower Eyelid Ectropion: A Case Report.
A pediatric patient developed cicatricial lower eyelid ectropion after two local excisions of a congenital melanocytic nevus at another institution.
Comparative efficacy of brain-computer interface-coupled robotic rehabilitation, robot-assisted therapy, and motor imagery for upper-limb motor recovery after stroke: a systematic review and network meta-analysis.
This systematic review and network meta-analysis evaluated the efficacy of brain-computer interface-coupled robotic rehabilitation (BCI-robot), robot-assisted therapy, motor imagery, and conventional rehabilitation for…
A previously unreported ELOVL4 frameshift variant in a patient with early severe cognitive decline, parkinsonism, and cerebellar ataxia: A case report.
A 35-year-old man presented with a 5-year history of progressive cognitive decline, parkinsonism, and cerebellar ataxia. Neurological examination revealed significant motor and cognitive impairments, with imaging…
Giant subpatellar synovial osteochondromatosis complicated by osteoarthritis of the knee: A case report.
A 71-year-old woman presented with a 2-year history of progressive pain and swelling in her left knee, leading to significant movement restriction and impairment in daily activities.
Power Doppler ultrasonography for positional graft compression after femoral artery reconstruction: A case report.
A 35-year-old male presented with pain and numbness during deep knee flexion, 3.5 years post-femoral artery reconstruction using the great saphenous vein.
Comparative efficacy of various non-pharmacological therapies on cognitive function in patients with mild cognitive impairment or dementia: A network meta-analysis.
This network meta-analysis evaluated the efficacy of non-pharmacological therapies on cognitive function in 2082 patients with mild cognitive impairment or dementia.
Critical Kennedy's disease with Guillain-Barré syndrome and respiratory failure: A case report.
A 61-year-old man with a 35-year history of Kennedy disease presented with acute respiratory failure, dysphagia, and progressive dyspnea.
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