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2000 articles

October 202624

Clinical ResearchEndocrinology

Retatrutide and lipid and metabolite profiles in participants with obesity with or without type 2 diabetes.

This post hoc exploratory analysis of two randomized, placebo-controlled phase 2 trials examined fasting plasma metabolite and lipid changes with retatrutide in participants with obesity, with or without type 2…

J Clin Endocrinol MetabOct 16, 2026Read summary
Clinical ResearchPhysical Medicine & Rehabilitation

Kinematic adaptations of the uppercut punch following an eight-week biomechanics-based training intervention in amateur boxers.

This randomized controlled trial examined whether an eight-week biomechanics-based program changed right-hand uppercut mechanics in 24 male amateur boxers with 3–4 years of training experience.

Acta Bioeng BiomechOct 16, 2026Read summary
Case ReportPsychiatry

Clinical Improvement Following Multimodal Treatment in Depersonalization-Derealization Disorder: A Case Report.

A patient with depersonalization-derealization disorder presented with derealization, emotional blunting, poor memory, slowed reactions, and impaired attention.

J Vis ExpOct 16, 2026Read case
Clinical ResearchEndocrinology

Efficacy and safety of imeglimin hydrochloride for metabolic dysfunction-associated steatotic liver disease with type 2 diabetes: Single-center, single-arm phase 2 (IMELD study).

This single-center, single-arm phase 2 interventional study assessed 24 weeks of imeglimin in patients with metabolic dysfunction-associated steatotic liver disease (MASLD) and type 2 diabetes.

Medicine (Baltimore)Oct 16, 2026Read summary
Clinical ResearchRadiology (Diagnostic)

Vacuum-Assisted Breast Biopsy and Excision for Breast Lesions: A Systematic Review and Meta-analysis of Malignant Upgrade in B3 Lesions.

This systematic review and meta-analysis examined malignant upgrade in B3 breast lesions assessed through diagnostic vacuum-assisted biopsy (VAB/VABB) or second-line vacuum-assisted excision (VAE).

J Vis ExpOct 16, 2026Read summary
Case ReportPediatrics

Cardiac arrest in an adolescent following an overdose of antidepressants comprising sertraline, quetiapine fumarate, and lamotrigine: Case report.

An 11-year-old with depression ingested large quantities of sertraline (3 g), quetiapine fumarate (5 g), and lamotrigine (3 g).

Int J Clin Pharmacol TherOct 16, 2026Read case
Case ReportNephrology

Crystalline κ light-chain proximal tubulopathy and Auer rod-like inclusions presenting as Fanconi syndrome: A case report.

A 53-year-old man presented with Fanconi syndrome, with hypokalemia, hypophosphatemia, mild metabolic acidosis, and renal glucosuria.

Clin NephrolOct 16, 2026Read case
Clinical ResearchNeurology

Repetitive transcranial magnetic stimulation for the treatment of restless legs syndrome: A meta-analysis.

This meta-analysis examined repetitive transcranial magnetic stimulation (rTMS) versus sham stimulation for restless legs syndrome (RLS), pooling four eligible studies.

Medicine (Baltimore)Oct 16, 2026Read summary
Clinical ResearchOrthopedic Surgery

Artificial intelligence empowering the diagnosis and treatment of rotator cuff tears: A systematic review from image optimization to prognosis prediction.

This systematic review examined original studies applying artificial intelligence across the rotator cuff tear care pathway, including imaging, diagnosis, anatomical measurement, and prognosis.

Medicine (Baltimore)Oct 16, 2026Read summary
Clinical ResearchCardiology

Psychological Stress and the Diurnal Patterns of Sodium Excretion and Blood Pressure: Results From the SABRE Study.

The SABRE study examined whether urinary sodium responses to mental stress were associated with day–night sodium excretion patterns and systolic blood pressure (BP) dipping in apparently healthy adults.

J Am Heart AssocOct 16, 2026Read summary
Case ReportCardiothoracic Surgery

Large Carinal Chondrosarcoma: Resection of the Main Carina, Distal Trachea, and Orifices of the Mainstem Bronchi and Construction of a New Carina.

A 23-year-old man presented with dyspnea, fatigue, and cough. CT showed a lobulated mass anterior to the distal trachea and main carina; bronchoscopy demonstrated carinal widening, significant stenosis of both mainstem…

Am J Case RepOct 16, 2026Read case
Case ReportCardiothoracic Surgery

En bloc excision of a large hydatid cyst originating from the posterior wall of the left ventricle.

A male patient was found incidentally to have a hydatid cyst arising from the posterior wall of the left ventricle. The cyst was completely removed en bloc through a left ventriculotomy.

Multimed Man Cardiothorac SurgOct 16, 2026Read case
Case ReportOncology (Medical)

WIN-MTB-2024002 - WIN International Molecular Tumor Board: A 52-year-old female with unmeasurable Stage IIIc colon cancer.

A 52-year-old woman with stage IIIc colon cancer had KRAS, TP53, IDH1, and APC mutations, high tumor PD-L1 expression, and elevated VEGFR1 and VEGFR3.

OncotargetOct 16, 2026Read case
Case ReportOncology (Medical)

Tislelizumab-induced hyperamylasemia: Case report and safety analysis using the FAERS database.

A 69-year-old patient developed hyperamylasemia after six cycles of combination immunotherapy with pemetrexed, tislelizumab, and carboplatin. The authors attributed the elevated amylase to tislelizumab.

Int J Clin Pharmacol TherOct 16, 2026Read case
Case ReportHematology

Variability in belumosudil exposure due to coadministration of voriconazole and isavuconazole in a patient with chronic graft-versus-host disease: Case report.

A man in his 50s with steroid-refractory pulmonary chronic graft-versus-host disease after cord blood transplantation received belumosudil, increased from 200 mg once daily to 200 mg twice daily.

Int J Clin Pharmacol TherOct 16, 2026Read case
Clinical ResearchCardiology

Chios Mastic in Well-Controlled Hypertension: Findings From the HYPER-MASTIC Randomized Controlled Trial.

This double-blind, randomized, placebo-controlled trial assessed whether Chios mastic provides additional cardiovascular benefits in 106 adults with stable, well-controlled hypertension.

Pharmacol Res PerspectOct 16, 2026Read summary
Clinical ResearchNeurologyOpen access

Tenecteplase, alteplase, and endovascular thrombectomy in extended-window acute ischemic stroke with intracranial large-vessel occlusion: a Bayesian network meta-analysis.

This Bayesian network meta-analysis compared reperfusion strategies in imaging-selected patients with acute ischemic stroke treated 4.5 to 24 hours after onset or last known well.

J NeurolOct 16, 2026Read summary
Case ReportNeurologyOpen access

A novel de novo variant of CDKL5 in an Iranian child with infantile-onset refractory epilepsy.

An Iranian girl presented with developmental delay, hypotonia, and refractory seizures. Whole-exome sequencing identified a de novo CDKL5 frameshift variant, c.1037_1038delTCinsCAGATCTAA (p.Ile346Thrfs*14), which Sanger…

Mol Biol RepOct 16, 2026Read case
Clinical ResearchUrologyOpen access

Preoperative ureteral rest and outcomes of robot-assisted upper urinary tract reconstruction: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed whether preoperative ureteral rest is associated with outcomes after robot-assisted ureteral reconstruction or pyeloplasty.

J Robot SurgOct 16, 2026Read summary
Case ReportPulmonology

Life-threatening diffuse alveolar hemorrhage associated with Rhinovirus infection and the potential role of corticosteroids in immunocompetent patients: Case reports.

Two immunocompetent women, aged 85 and 70, presented with severe hypoxemia and hemoptysis or worsening dyspnea. Chest CT showed diffuse or bilateral ground-glass opacities and consolidations.

Medicine (Baltimore)Oct 16, 2026Read case
Case ReportOncology (Medical)Open access

Management of extravasations of enfortumab vedotin and pembrolizumab: a case report and mini review of the current literature.

A 56-year-old patient with metastatic urothelial carcinoma developed extravasation of enfortumab vedotin and pembrolizumab during the first treatment cycle after the port catheter dislocated from the cephalic vein.

J Cancer Res Clin OncolOct 16, 2026Read case
Clinical ResearchOrthopedic SurgeryOpen access

Effectiveness of different autologous platelet concentrates for orthodontic canine retraction following premolar extraction: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed platelet-rich plasma (PRP), injectable platelet-rich fibrin (i-PRF), and leukocyte-platelet-rich fibrin (L-PRF) for accelerating orthodontic canine retraction after…

Prog OrthodOct 16, 2026Read summary
Case ReportGastroenterology

Acute colonic variceal bleeding treated with coil-assisted retrograde transvenous obliteration following atezolizumab-bevacizumab therapy for advanced hepatocellular carcinoma: A case report.

A 66-year-old man with alcohol-related cirrhosis and advanced hepatocellular carcinoma developed hematochezia the day after starting atezolizumab plus bevacizumab.

Medicine (Baltimore)Oct 16, 2026Read case
Clinical ResearchCardiology

Artificial intelligence-enhanced electrocardiography for predicting mortality and major adverse cardiovascular events: A systematic review and narrative synthesis.

This systematic review and narrative synthesis evaluated AI-enabled 12-lead or single-lead ECG models for predicting all-cause mortality, cardiovascular mortality, and major adverse cardiovascular events in adults.

PLoS OneOct 16, 2026Read summary

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