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2000 articles
September 202624
Dexketoprofen Trometamol Plus Sufentanil for Analgesia After Thoracoscopic Radical Resection of Lung Cancer: A Randomized, Double-Blind, Placebo-Controlled Trial.
Evidence for adding dexketoprofen trometamol to sufentanil-based patient-controlled intravenous analgesia (PCIA) after thoracoscopic radical resection of lung cancer remains limited.
Tegileridine versus Sufentanil for Patient-Controlled Intravenous Analgesia After Cesarean Delivery: A Randomized Double-Blind Trial.
Postoperative nausea and vomiting (PONV) remains one of the most common opioid-related adverse events after cesarean delivery despite multimodal analgesia.
Thalamic Tuberculoma Presenting as Isolated Gait Disturbance Without Systemic or Meningeal Symptoms in a 2-Year-Old Child: A Case Report.
A 2-year-old boy presented with isolated gait disturbance and decreased power on the left side, without systemic or meningeal symptoms.
Saprochaete pneumonia presenting as septic shock in an elderly patient with poorly controlled diabetes mellitus.
An elderly woman with poorly controlled diabetes presented with community-acquired pneumonia, septic shock, and multi-organ dysfunction. Despite initial antibiotic treatment, her condition deteriorated.
A specialist-led interprofessional weaning program to prevent weaning failure in high-risk patients: the PRiVENT study.
The PRiVENT study evaluated a specialist-led interprofessional weaning program for high-risk mechanically ventilated patients in a multicenter, non-randomized trial.
A phase 1b/2 study of ceralasertib, a selective inhibitor of ATR, in patients with relapsed or refractory MDS and CMML.
This phase 1b/2 study evaluated ceralasertib, an ATR inhibitor, in 44 adults with relapsed or refractory MDS and CMML. The overall response rate was 29.5%, with a median progression-free survival of 4.8 months and…
Right Brain: Language Without Speech.
During a neurology rotation as a second-year internal medicine resident, I encountered a preschool-aged child whose absence of spontaneous speech initially framed my clinical thinking.
Implementation of Total Body Photography for Skin Cancer Early Detection: A Systematic Review.
This systematic review examined how total body photography (TBP) has been implemented and used for skin cancer detection and surveillance across healthcare settings.
Metastatic muscle invasive bladder cancer in pregnancy.
A woman in her 30s presented during the second trimester with hematuria and left flank pain. MRI identified a T3b bladder tumor with suspected peritoneal invasion.
A phase 1/1b study of the all-oral regimen CC-486 and venetoclax in acute myeloid leukemia.
This phase 1/1b study evaluated the all-oral regimen of CC-486 and venetoclax in patients with relapsed, refractory, and newly diagnosed acute myeloid leukemia (AML).
Anakinra versus intramuscular methylprednisolone acetate for gout flares in people with chronic kidney disease (ASGARD): a UK randomised multicentre, double-blind, double-dummy controlled feasibility study with economic, qualitative and safety assessment.
The ASGARD study was a feasibility randomized controlled trial comparing anakinra to intramuscular methylprednisolone acetate for treating gout flares in patients with chronic kidney disease.
'Once Bitten': A Case of Tetanus Following Snakebite in Australia.
A 58-year-old woman in Victoria, Australia, presented after a suspected Tiger snake bite. She was not current with her tetanus vaccination and did not receive a booster.
Impact of EBV status and histology on patient outcomes with nivolumab-AVD vs BV-AVD in advanced classic Hodgkin lymphoma (S1826).
This phase 3 randomized controlled trial evaluated the impact of EBV status and histology on outcomes in patients with advanced classic Hodgkin lymphoma treated with nivolumab-AVD (N-AVD) versus brentuximab vedotin-AVD…
Intracardiac vs. transesophageal echocardiography in patients undergoing ablation for atrial fibrillation: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the safety and efficacy of intracardiac echocardiography (ICE) versus transesophageal echocardiography (TEE) in 7671 patients undergoing catheter ablation for atrial…
Efficacy of pancreatic enzyme replacement therapy on exocrine pancreatic insufficiency: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the efficacy of pancreatic enzyme replacement therapy (PERT) in improving nutrient absorption in patients with exocrine pancreatic insufficiency (EPI).
Continuous Intravenous Acyclovir as Outpatient Parenteral Antimicrobial Therapy for HSV and VZV Neurological Infections: A Case Series With Pharmacokinetic and Cost Evaluation, and Review of Literature.
This case series involved eight patients with neurological infections caused by HSV or VZV who transitioned to continuous intravenous acyclovir via an outpatient parenteral antimicrobial therapy (OPAT) program after…
A meta-analysis of transjugular intrahepatic portosystemic shunt with or without embolization for esophageal and gastric variceal bleeding in decompensated liver cirrhosis.
This meta-analysis evaluated the efficacy of transjugular intrahepatic portosystemic shunt (TIPS) with or without embolization in 3079 patients with decompensated liver cirrhosis experiencing esophageal and gastric…
Percutaneous catheter drainage versus needle aspiration for liver abscess: a systematic review and meta-analysis of efficacy and safety.
This systematic review and meta-analysis evaluated the efficacy and safety of percutaneous catheter drainage (PCD) versus needle aspiration (PNA) for liver abscesses in 1425 adults.
Efficacy and safety of tegoprazan-amoxicillin dual therapy versus bismuth-containing quadruple therapy for first-line Helicobacter pylori eradication: a systematic review and meta-analysis of randomized controlled trials.
This systematic review and meta-analysis evaluated the efficacy and safety of 14-day tegoprazan-amoxicillin dual therapy versus bismuth-containing quadruple therapy (BQT) for first-line Helicobacter pylori eradication…
Methods for a Community-Engaged Randomized Trial for Urgency Incontinence.
The Beta-Agonist versus ONA Trial for Urgency Urinary Incontinence (BEST) is a multicenter, single-blinded randomized trial comparing the efficacy of beta-agonist medication and onabotulinumtoxinA injections in female…
Imaging biomarkers for cardiometabolic risk stratification in metabolic dysfunction-associated steatotic liver disease: incremental value of coronary artery calcification, epicardial adipose tissue, controlled attenuation parameter, and liver stiffness measurement beyond clinical scores.
This systematic review analyzed 16 observational studies involving 34,713 adults with metabolic dysfunction-associated steatotic liver disease (MASLD) to evaluate the association between MASLD and imaging biomarkers of…
Effect of early regional anesthesia on postoperative cognitive function and the perioperative stress response in patients with hip fractures: a randomized controlled trial.
This randomized controlled trial investigated the effect of anterior iliopsoas muscle space block (AIMSB) timing on postoperative delirium (POD) in 79 elderly patients undergoing total hip arthroplasty for fractures.
Sex differences in the efficacy, acceptability, and tolerability of antipsychotics in people with acute schizophrenia: individual participant data pairwise, dose-response, and network meta-analyses.
This individual participant data pairwise, dose-response, and network meta-analysis examined sex differences in antipsychotic efficacy, acceptability, and tolerability in adults with acute schizophrenia.
Prognostic Models for Predicting the Severity and Mortality in People With Acute Pancreatitis - A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed how accurately four clinical scoring systems predict severe acute pancreatitis (SAP) and mortality in adults.
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