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2000 articles
October 202624
Extensive Arterial Thrombosis Complicating Acute Pancreatitis: A Case Report and Literature Review.
A 61-year-old man with chronic pancreatitis developed acute interstitial edematous pancreatitis. Four weeks after presentation, persistent dyspepsia prompted contrast-enhanced CT, which showed pancreatic pseudocysts and…
Prognostic associations between patient-reported outcomes and progression-free and overall survival in advanced gastric or gastroesophageal junction adenocarcinoma with PD-L1 TAP score ≥ 5%: results from the RATIONALE-305 trial.
This analysis of the randomised RATIONALE-305 trial examined whether longitudinal patient-reported outcomes (PROs) were associated with progression-free survival (PFS) and overall survival (OS) in patients with advanced…
Fishbone-Induced Gastrointestinal Perforation: A 21-Case Series from Vietnam.
This retrospective series included 21 patients treated for fishbone-induced gastrointestinal perforation at a tertiary hospital in southern Vietnam.
Tricuspid Chordae Tendineae Rupture Detected After Repair of a Delayed Traumatic Left Ventricular Aneurysm: A Case Report.
After a fall from a height, a patient presented 54 days later with rupture of a posterior left ventricular aneurysm. Venoarterial extracorporeal membrane oxygenation provided circulatory support before surgical aneurysm…
Neoadjuvant short-course radiotherapy followed by camrelizumab and chemotherapy versus standard of care for locally advanced rectal cancer (UNION): a prespecified interim analysis of a multicentre, open-label, randomised, phase 3 trial.
UNION was a multicentre, open-label, randomised phase 3 trial at nine hospitals in China comparing neoadjuvant short-course radiotherapy followed by camrelizumab plus CAPOX with long-course chemoradiotherapy followed by…
Stereotactic body radiation therapy for pancreatic cancer: evaluating its efficacy, safety, and future prospects: systematic review.
This systematic narrative review assessed stereotactic body radiation therapy (SBRT) for locally advanced pancreatic cancer, including patients unsuitable for surgery.
A 66-Year Old Female with Belly Dancer's Syndrome: A Case Report from a Low-Resource Setting.
A 66-year-old woman with well-controlled hypertension had a 15-year history of intermittent jerky abdominal-wall movements, preceded by a burning epigastric sensation and associated with abdominal pain, dyspnoea and…
Persistent Microfilaremia Caused by Dirofilaria asiatica Infection in 2-Year-Old Child, Sri Lanka, 2024.
A 2-year-old child in Sri Lanka was found to have a patent infection with Dirofilaria asiatica, a canine filarioid implicated in zoonotic human infection.
Combination therapy of carbon dioxide laser with topical halometason cream and 308 nm excimer laser for the treatment of vitiligo: an optimized combined treatment protocol.
This randomized controlled trial evaluated fractional CO₂ laser plus topical halometasone cream and 308-nm excimer lamp therapy for refractory non-segmental vitiligo, compared with excimer therapy, a topical calcineurin…
Informal Caregiver-Observed Fall Risk Indicators and Caregiver Responses to Prevent Falls Among Community-Dwelling Older People: A Systematic Review.
This systematic review synthesized 16 studies of informal caregivers’ observations of fall-risk indicators and their preventive responses among community-dwelling older people.
Copy number variants across the developmental epilepsy-developmental and epileptic encephalopathy spectrum: an Indonesian case series.
A retrospective series from a tertiary hospital in Yogyakarta described four Indonesian children with developmental epilepsy or developmental and epileptic encephalopathy and pathogenic copy number variants.
Dirofilaria asiatica Infection and Asymptomatic Microfilaremia, Sri Lanka, 2025.
During night blood surveillance for lymphatic filariasis in Sri Lanka in 2025, two people were found to have asymptomatic Dirofilaria microfilaremia.
HHV8-associated multicentric Castleman disease with Kaposi sarcoma in an immunocompetent patient: a case report and review of the literature.
A 57-year-old man presented with five months of generalized lymphadenopathy, weakness, cough, fever, and weight loss. HIV, CMV, EBV, and tuberculosis tests were negative.
Efficacy and safety of GLP-1 receptor agonists for antipsychotic-related overweight and metabolic dysregulation: a systematic review and meta-analysis.
This systematic review and meta-analysis pooled randomized controlled trials of GLP-1 receptor agonists in adults receiving antipsychotic treatment for overweight or metabolic dysregulation.
Presumed non-inflammatory bilateral peripapillary subretinal fibrosis in adolescent patients.
Two adolescents presented with bilateral peripapillary subretinal fibrotic lesions and no overt clinical or angiographic evidence of active intraocular inflammation.
Systemic Spiroplasma turonicum Infection Manifested as Knee Arthritis, France, 2025.
An immunocompromised patient in southeast France presented with fever, knee arthritis, and skin erythema. Blood and joint samples tested positive for Spiroplasma turonicum, an intracellular gram-negative bacterium…
Mapping the prevalence of Epstein-Barr virus and multiple sclerosis in Middle East and North Africa: a systematic review and meta-analysis.
This systematic review and meta-analysis mapped published estimates of multiple sclerosis (MS) prevalence and Epstein-Barr virus (EBV) seroprevalence in Middle East and North Africa populations.
Clinical manifestations of Armfield syndrome in females with heterozygous FAM50A variants and skewed X-chromosome inactivation.
A Spanish female patient presented with macrocephaly, global developmental delay, and leukoencephalopathy. Whole-exome sequencing identified a novel de novo heterozygous FAM50A variant, c.905 A > T (p.His302Leu).
Digital Therapeutic Interventions for Suicide Prevention: A Systematic Review and Meta-Analysis of Their Effectiveness in Reducing Suicidal Ideation and Suicide Attempts.
This systematic review and meta-analysis synthesised randomized clinical trials of digital interventions for suicide prevention. Seventeen studies (N = 5.089) were included.
Disseminated Trimethoprim/Sulfamethoxazole-Resistant Nocardiosis in Renal Transplant Recipient, India.
A renal transplant recipient in India taking trimethoprim/sulfamethoxazole prophylaxis presented with fever, hemoptysis, and neurologic deficits.
Efficacy and safety of mitapivat in patients with sickle cell disease (RISE UP): a phase 3, double-blind, global, randomised, placebo-controlled trial.
RISE UP was a phase 3, double-blind, global, randomised, placebo-controlled trial conducted at 69 sites in 15 countries. It evaluated twice-daily mitapivat in patients older than 16 years with sickle cell disease…
Varicella zoster vasculopathy presenting as bilateral subdural haematoma in an infant: case report of a rare case and literature review.
A 6-month-old boy developed chickenpox with fever, irritability, and a vesicular rash. Although the rash and fever resolved, he had persistent irritability, poor feeding, intermittent vomiting, developmental regression…
Evaluating the effectiveness of the eHealth-faciLitated SMILe-integrated care model on treatment burden, quality of life and graft-versus-host disease after allogeneic stem cell transplantation: results of two European randomized controlled implementation studies.
Two multicentre, hybrid effectiveness-implementation randomised controlled trials at European allogeneic stem cell transplantation (alloSCT) centres evaluated SMILe-ICM, an eHealth-supported, advanced practice nurse-led…
Cine Magnetic Resonance Imaging for Assessing Chest Wall Invasion in Lung Cancer: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated cine MRI for detecting chest wall invasion in lung cancer, using surgical and histopathologic findings as the reference standard.
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