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2000 articles

October 202624

Clinical ResearchOrthopedic SurgeryOpen access

Acute management of pelvic ring injuries: identifying common treatment principles across institutional algorithms.

This PRISMA-guided systematic review compared published institutional algorithms for acute pelvic ring injury management. Searches identified 25 studies describing algorithms, pathways, or protocols published from 2006…

Eur J Orthop Surg TraumatolOct 16, 2026Read summary
Case ReportPathology (Anatomic & Clinical)Open access

Lymphoplasmacytic Lymphoma Involving Marrow-Containing Submandibular Heterotopic Ossification: A Case Report and Literature Review.

A 77-year-old man presented with a gradually enlarging, increasingly uncomfortable calcified nodule in the left submandibular region.

Head Neck PatholOct 16, 2026Read case
Clinical ResearchPathology (Anatomic & Clinical)Open access

SOX10 Expression in Primary Salivary Gland Tumors: A Meta-Analysis.

This PRISMA-guided systematic review and meta-analysis assessed SOX10 immunohistochemical expression across primary salivary gland tumors. It included 35 studies comprising 1146 histological and 35 cytological samples.

Head Neck PatholOct 16, 2026Read summary
Case ReportOncology (Medical)Open access

Management of extravasations of enfortumab vedotin and pembrolizumab: a case report and mini review of the current literature.

A 56-year-old patient with metastatic urothelial carcinoma developed extravasation of enfortumab vedotin and pembrolizumab during the first treatment cycle after the port catheter dislocated from the cephalic vein.

J Cancer Res Clin OncolOct 16, 2026Read case
Clinical ResearchCardiology

Artificial intelligence-enhanced electrocardiography for predicting mortality and major adverse cardiovascular events: A systematic review and narrative synthesis.

This systematic review and narrative synthesis evaluated AI-enabled 12-lead or single-lead ECG models for predicting all-cause mortality, cardiovascular mortality, and major adverse cardiovascular events in adults.

PLoS OneOct 16, 2026Read summary
Clinical ResearchEndocrinology

Retatrutide and lipid and metabolite profiles in participants with obesity with or without type 2 diabetes.

This post hoc exploratory analysis of two randomized, placebo-controlled phase 2 trials examined fasting plasma metabolite and lipid changes with retatrutide in participants with obesity, with or without type 2…

J Clin Endocrinol MetabOct 16, 2026Read summary
Case ReportNeurologyOpen access

A novel de novo variant of CDKL5 in an Iranian child with infantile-onset refractory epilepsy.

An Iranian girl presented with developmental delay, hypotonia, and refractory seizures. Whole-exome sequencing identified a de novo CDKL5 frameshift variant, c.1037_1038delTCinsCAGATCTAA (p.Ile346Thrfs*14), which Sanger…

Mol Biol RepOct 16, 2026Read case
Clinical ResearchPulmonology

The effects of multiregional fascial mobilization on heart rate and physiological parameters in patients with obstructive sleep apnea: A randomized controlled trial.

This randomized controlled trial assessed the acute physiological effects of a 16-minute multiregional fascial mobilization protocol in 95 men with polysomnography-confirmed moderate-to-severe obstructive sleep apnea.

Medicine (Baltimore)Oct 16, 2026Read summary
Clinical ResearchPsychiatryOpen access

Infant hippocampal and amygdala volume in an observational follow-up from a randomized clinical trial for maternal prenatal depression.

This observational follow-up examined brain volumes and later negative emotionality in 109 infants born to mothers who had participated in a randomized clinical trial of brief interpersonal psychotherapy for prenatal…

Nat CommunOct 16, 2026Read summary
Case ReportPulmonology

Life-threatening diffuse alveolar hemorrhage associated with Rhinovirus infection and the potential role of corticosteroids in immunocompetent patients: Case reports.

Two immunocompetent women, aged 85 and 70, presented with severe hypoxemia and hemoptysis or worsening dyspnea. Chest CT showed diffuse or bilateral ground-glass opacities and consolidations.

Medicine (Baltimore)Oct 16, 2026Read case
Case ReportAnesthesiology

Individualized multimodal pain management for chronic perineal pain: A case report.

A 68-year-old woman had three years of chronic perineal pain and tenderness that disrupted sleep, urination, and daily activities.

Medicine (Baltimore)Oct 16, 2026Read case
Case ReportRadiology (Diagnostic)Open access

Rare origin of the right inferior phrenic artery from the anterior inferior pancreaticoduodenal artery in a patient with hepatocellular carcinoma.

A woman in her 80s with ruptured hepatocellular carcinoma underwent emergency transcatheter arterial embolization. CT did not show the right inferior phrenic artery (RIPA) at its usual origins and suggested a source in…

Surg Radiol AnatOct 16, 2026Read case
Case ReportNeurosurgery

Arthroscopic-assisted uniportal spinal surgery with bone-anchored annular repair for far lateral lumbar disc herniation: A case report.

A 50-year-old woman had refractory lumbosacral and gluteal pain followed by right L3–L4-distribution radicular pain, limiting walking to less than 20 minutes despite conservative treatment.

Medicine (Baltimore)Oct 16, 2026Read case
Clinical ResearchAnesthesiology

Nociception Level-Guided Multimodal Analgesia with External Oblique Intercostal Plane Block in Laparoscopic Cholecystectomy.

This double-blind randomized controlled trial compared nociception level (NOL)-guided multimodal analgesia (MMA) incorporating an external oblique intercostal plane (EOIP) block with intravenous dexketoprofen alone in…

J Vis ExpOct 16, 2026Read summary
Case ReportEndocrinology

Approach to the patient with APS-1/APECED.

This article presents five cases of autoimmune polyendocrine syndrome type 1 (APS-1/APECED), a disorder caused by impaired immune tolerance and typically associated with biallelic AIRE variants.

J Clin Endocrinol MetabOct 16, 2026Read case
Clinical ResearchNephrology

Local ancestry-aware genome-wide meta-analysis uncovers novel genetic loci for sickle cell disease nephropathy.

This local ancestry-aware genome-wide association meta-analysis examined estimated glomerular filtration rate in participants from two well-characterized adult sickle cell disease cohorts, seeking genetic loci…

Blood AdvOct 16, 2026Read summary
Clinical ResearchMedical Genetics

The extra X chromosome and autoimmune susceptibility in Klinefelter syndrome.

This systematic review and meta-analysis assessed autoimmune susceptibility in people with Klinefelter syndrome (47,XXY), using studies of autoimmune disease and serological markers.

J Clin Endocrinol MetabOct 16, 2026Read summary
Clinical ResearchPediatrics

Sleep apnea-hypopnea in children: Evidence that Lize Tongqi decoction with acupuncture, moxibustion, and Xinwu acupoint stimulation is superior to standard Western treatment using montelucast/mometasone furoate.

This randomized controlled trial compared a combined traditional Chinese medicine and acupuncture-based regimen with montelukast plus mometasone in 60 children with snoring (mean age 7.9 years).

Int J Clin Pharmacol TherOct 16, 2026Read summary
Clinical ResearchCardiology

Chios Mastic in Well-Controlled Hypertension: Findings From the HYPER-MASTIC Randomized Controlled Trial.

This double-blind, randomized, placebo-controlled trial assessed whether Chios mastic provides additional cardiovascular benefits in 106 adults with stable, well-controlled hypertension.

Pharmacol Res PerspectOct 16, 2026Read summary
Case ReportPulmonology

Mixed Pneumonia with Pulmonary Embolism and Multiple Pathogens Detected in Bronchoalveolar Lavage Fluid: A Case Report.

A 72-year-old man presented with fever, nonproductive cough, vomiting, hypoxemia, elevated inflammatory markers, and an elevated D-dimer.

J Vis ExpOct 16, 2026Read case
Case ReportDermatology

Tranilast/roxithromycin with topical tacrolimus in refractory atopic facial eczema: Case report.

A 30-year-old man with atopic dermatitis had facial eczema and severe itching that persisted despite conventional treatment, including oral betamethasone.

Int J Clin Pharmacol TherOct 16, 2026Read case
Clinical ResearchCardiology

Optimal exercise modalities and doses for blood pressure management in adults with prehypertension and hypertension: A systematic review and Bayesian network meta-analysis.

This systematic review and Bayesian network meta-analysis compared structured exercise modalities and estimated doses for blood pressure reduction in adults with prehypertension or stage 1 or 2 hypertension.

MaturitasOct 16, 2026Read summary
Case ReportPediatrics

A case of neonatal gastric perforation misdiagnosed as neonatal necrotizing enterocolitis: A literature review.

A male infant born at 33 weeks and 5 days presented on day four of life with abdominal distension, feeding refusal, and no passage of flatus or stool.

Medicine (Baltimore)Oct 16, 2026Read case
Clinical ResearchNeurologyOpen access

Tenecteplase, alteplase, and endovascular thrombectomy in extended-window acute ischemic stroke with intracranial large-vessel occlusion: a Bayesian network meta-analysis.

This Bayesian network meta-analysis compared reperfusion strategies in imaging-selected patients with acute ischemic stroke treated 4.5 to 24 hours after onset or last known well.

J NeurolOct 16, 2026Read summary

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