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2000 articles
October 202624
Impact of Intermittent Preventive Treatment for Malaria in Pregnancy With Sulfadoxine-Pyrimethamine, Dihydroartemisinin-Piperaquine, and Their Combination on Infant Outcomes: A Randomized Controlled Trial.
This double-blind randomized controlled trial compared infant malaria and growth outcomes after maternal intermittent preventive treatment in pregnancy with sulfadoxine-pyrimethamine (SP), dihydroartemisinin-piperaquine…
MACULAR CHOROIDAL NEOVASCULARIZATION IN PERIPAPILLARY HYPERREFLECTIVE OVOID MASS-LIKE STRUCTURES: CASE REPORT.
A healthy 36-year-old woman presented with three days of vision loss in her right eye. Optical coherence tomography of the optic nerve head showed peripapillary hyperreflective ovoid mass-like structures (PHOMS), while…
SARS-CoV-2 Vaccination and Attenuation of Breakthrough Infection Severity: A Systematic Global Review and Meta-analysis.
This systematic review and meta-analysis examined whether COVID-19 vaccination attenuates disease severity among people with breakthrough infections, using global observational studies reporting matched…
Treatment of Progressive Multifocal Leukoencephalopathy With Third-Party Allogeneic BK Virus T Cells.
This single-center phase 2 study evaluated third-party, partially HLA-matched BK virus-specific T cells in 37 patients with progressive multifocal leukoencephalopathy (PML), including 23 with hematologic malignancy.
RETINAL VASCULITIS ASSOCIATED WITH TYPE M2 ANTIMITOCHONDRIAL ANTIBODIES.
A 35-year-old woman presented with photopsia but no reduction in visual acuity. Examination showed bilateral retinal vasculitis, predominantly venous and more extensive in the left eye, involving both central and…
METALLIC RETINAL ARTERY EMBOLUS AFTER PIPELINE EMBOLIZATION DEVICE.
A 41-year-old woman who had undergone two Pipeline embolization device procedures for a left ophthalmic artery aneurysm was referred after an incidental refractile object was seen in the left macula.
Effect of photobiomodulation on recovery from oral soft tissue local anaesthesia in paediatric patients: a preliminary split-mouth randomized clinical trial.
This preliminary split-mouth randomized clinical trial assessed whether 810-nm diode laser photobiomodulation (PBM) shortened oral soft-tissue anaesthesia after infiltration local anaesthesia in 34 children aged 8–12…
Emergency thoracoabdominal aortic repair: distal-first approach with two previous aortic repairs.
A 59-year-old man with preoperative haemodialysis and two prior aortic repairs—a frozen elephant trunk for acute type A dissection and subsequent thoracic endovascular repair—presented with chest pain.
COLOBOMA ASSOCIATED WITH VACTERL CHARACTERIZED BY ULTRA-WIDEFIELD OPTICAL COHERENCE TOMOGRAPHY.
A 34-week-old infant admitted for repair of type C tracheoesophageal fistula with esophageal atresia and management of pelviectasis and low conus medullaris underwent routine retinopathy of prematurity screening.
Robot-assisted versus conventional cranial stereotactic neurosurgery: a systematic review and meta-analysis of targeting accuracy, procedural efficiency, and safety.
This systematic review and meta-analysis compared robot-assisted with conventional cranial stereotactic neurosurgery across 21 comparative studies, examining targeting accuracy, procedural efficiency, safety and…
Familial Glioma in a Father and Son: Integrated Genomic and Multi-compartment Proteomic Profiling.
A 60-year-old father and his 35-year-old son presented with gliomas. The father’s tumor was glioblastoma, IDH-wildtype, WHO grade 4, with an unmethylated MGMT promoter; the son’s was astrocytoma, IDH-mutant, WHO grade…
Multimedia versus audio-based education for improving dentists' nutrition-related knowledge and behavior: A randomized comparative study.
This randomized comparative trial assessed whether multimedia or audio-based education improved nutrition-related knowledge and self-reported behavior among 166 general dentists in Tehran.
Mind Your Heart-A Web-Based Dietary Approaches to Stop Hypertension Diet and Mindful Eating Intervention for Working Adults at Elevated Cardiovascular Risk: Pilot Randomized Controlled Trial.
This pilot randomized controlled trial assessed the feasibility and preliminary effects of a six-week, self-guided web-based DASH education program, with or without mindful eating instruction, among working adults at…
Neck-Specific Exercises With Internet Support Versus Standard Neck-Specific Exercise for the Treatment of Chronic Whiplash-Associated Disorders: Cost-Effectiveness Analysis.
This prospective, multicenter randomized controlled trial compared a 3-month internet-supported neck-specific exercise program plus four physiotherapy visits (NSEIT) with clinic-based neck-specific exercise twice weekly…
Dengue virus controlled human challenge reveals that preexisting immunity shapes viral replication and broadly protective responses.
This phase 1 controlled human challenge trial enrolled 45 healthy adults to examine how preexisting immunity shapes responses to heterotypic dengue virus challenge.
ACUTE BILATERAL RETINAL AND CHOROIDAL DETACHMENT-A CASE REPORT.
A 57-year-old man developed profound bilateral visual loss while hospitalized with sepsis of unknown cause and was referred three weeks later with bilateral retinal detachment.
A NETwork meta-analysis with COST-effectiveness evaluation of pharmacological treatments for heart failure with reduced ejection fraction: NET-COST-HFrEF.
This network meta-analysis of 47 randomized controlled trials involving 75,978 patients with heart failure with reduced ejection fraction assessed guideline-directed drug combinations and their cost-effectiveness.
Subgroup Analysis of Pooled Phase 3 Efficacy Data From Two Randomized Trials of Gepotidacin Versus Nitrofurantoin in Uncomplicated Urinary Tract Infections (EAGLE-2 and EAGLE-3) Including Participants With Uropathogens Not-Susceptible to Nitrofurantoin.
This pooled subgroup analysis of two phase 3 randomized trials compared gepotidacin with nitrofurantoin in female participants aged ≥12 years with uncomplicated urinary tract infections.
Impact of Chatbot-Based Cognitive Training on Cognitive Function and White Matter Integrity in Cognitively Unimpaired Older Adults: Randomized Controlled Trial.
This single-blind randomized controlled trial evaluated chatbot-based cognitive training in 72 cognitively unimpaired older adults.
Efficacy and Safety of Ushaq Capsule as Adjunctive Therapy in Patients With Lumbar Radiculopathy: A Double-Blind, Randomized, Placebo-Controlled Clinical Trial at Imam Khomeini Hospital, Tehran, Iran.
This double-blind, randomized, placebo-controlled trial evaluated Ushaq capsules as adjunctive therapy in 68 patients with lumbar radiculopathy.
IDIOPATHIC RETINITIS VASCULITIS ANEURYSMS AND NEURORETINITIS (IRVAN) TREATED WITH ADALIMUMAB: A CASE REPORT.
An adolescent with idiopathic retinal vasculitis, aneurysms, and neuroretinitis (IRVAN) was initially treated with panretinal photocoagulation and intravitreal ranibizumab in both eyes.
A Randomized, Double-Blind, Placebo-Controlled Study of the PD-1 Inhibitor Cetrelimab in Chronic Hepatitis B.
This randomized, double-blind, placebo-controlled study assessed the safety, activity and pharmacokinetics of a single low dose of the PD-1 inhibitor cetrelimab in adults with chronic hepatitis B virologically…
Postoperative Pain Treatment After Pancreatic Surgery: A Systematic Review With Meta-Analyses and Trial Sequential Analyses.
This PROSPERO-registered systematic review and meta-analysis examined postoperative analgesia after total pancreatectomy, pancreaticoduodenectomy, and distal pancreatectomy.
Recurrent Nodular Lymphocyte Predominant Hodgkin Lymphoma with Diagnostic Evolution Over Two Decades.
A 51-year-old man had a nearly 20-year history of nodular lymphocyte predominant Hodgkin lymphoma (NLPHL), with multiple relapses and prolonged remissions.
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