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2000 articles
October 202624
Locus coeruleus abnormalities on neuromelanin-sensitive MRI in Parkinson's disease: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed locus coeruleus (LC) integrity on neuromelanin-sensitive MRI in Parkinson’s disease (PD), pooling independent comparisons with healthy controls using random-effects…
Beyond Hereditary Haemorrhagic Telangiectasia (HHT): Capillary Malformation-Arteriovenous Syndrome (CM-AVM).
An asymptomatic woman in her forties was referred for suspected hereditary haemorrhagic telangiectasia (HHT) after mucocutaneous telangiectasia was noted on her face, lips and hands.
Avatar-led digital health intervention for sexual and gender minority young adult smoking cessation: randomized controlled pilot trial.
This randomized controlled pilot trial compared EQQUAL, an Acceptance and Commitment Therapy-based digital smoking cessation program tailored for sexual and gender minority (SGM) young adults, with Smokefree.gov.
Randomized controlled trial of a group-based smoking cessation intervention for adults with serious mental illness.
This randomized controlled trial evaluated PARQuit in 99 adults with serious mental illness in the United States. Participants received 12 weeks of cessation counseling and pharmacotherapy and were assigned to…
Early exercise therapy for acute nephrotic syndrome: a randomised clinical trial.
This single-centre randomised controlled trial assessed early exercise therapy in hospitalised adults receiving glucocorticoids for acute nephrotic syndrome.
Effects of exposure to negative and positive social media content about vaping and nicotine addiction on beliefs and intentions to use e-cigarettes among young adults in the United States: results from a randomized controlled experiment.
This randomized controlled experiment assigned 1,816 young adults in the United States to view real, publicly accessible social media videos presenting nicotine addiction positively, negatively, or in unrelated control…
Crescents in native kidney biopsies from patients with IgA nephropathy and the risk of recurrence after kidney transplantation: a retrospective cohort study, systematic literature review and meta-analysis of observational studies.
This retrospective cohort study, systematic review and meta-analysis examined whether glomerular crescents in native kidney biopsies predict IgA nephropathy (IgAN) recurrence after kidney transplantation.
From inference to proof: nanopore sequencing confirms zoonotic Neisseria Zoodegmatis peritonitis after cat bite-related contamination in a patient on automated peritoneal dialysis.
A 90-year-old patient receiving automated peritoneal dialysis developed peritonitis after a cat bite damaged the transfer set. Empirical therapy produced only a partial response, followed by relapse.
Unexpected finding of AA amyloidosis with novel genetic variants in the MEFV gene in patients undergoing kidney biopsy for proteinuria. A case series.
The report describes patients undergoing kidney biopsy for proteinuria in whom AA amyloidosis was identified, alongside MEFV gene variants.
Molecular-genetic mechanisms of cerebral arteriovenous malformations: A systematic review of germline, somatic and experimental evidence.
This systematic review synthesised human genetic, molecular, and experimental evidence on cerebral arteriovenous malformation (AVM) formation, clinical course, and potential therapeutic targets.
Thulium laser-assisted delivery of growth factors for treating androgenetic alopecia - a randomized, controlled, clinical study.
This pilot randomized controlled study evaluated non-ablative fractional laser (NAFL)-assisted delivery of a biomimetic growth factor serum, with or without red light therapy, in patients with androgenetic alopecia.
Clinical Outcomes and Complications of Extracorporeal Membrane Oxygenation (ECMO) in Adult Patients With COVID-19 in Central and Eastern Europe: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis pooled observational studies of adults with COVID-19 treated with ECMO in Central and Eastern Europe. Twelve studies covered 802 patients from six countries.
Patients with MASH experience worse health-related quality of life: a multinational real-world study using LiverMultiScan.
This multinational real-world randomised controlled trial examined health-related quality of life (HRQoL) and liver MRI markers in 802 people with suspected MASLD/MASH across four European countries.
Ianalumab for the Treatment of Patients with Sjögren's Disease.
Two 52-week, double-blind, randomized, placebo-controlled phase III trials evaluated monthly or less frequent ianalumab in patients with active Sjögren's disease.
A self-controlled case series to evaluate the effects of clinical trial eligibility criteria on biologic-associated reductions in severe asthma exacerbations: an analysis of the CHRONICLE study.
This study examined whether eligibility criteria used in biologic trials identify adults with severe asthma who are more likely to benefit.
Hyponatremic-Hypertensive Syndrome as a Rare Manifestation of Renovascular Hypertension: A Case Series.
Two girls, aged 4 and 9 years, presented with severe hypertension and electrolyte disturbances, including hyponatremia and hypokalemia, with elevated renin-aldosterone activity.
Effectiveness of tocilizumab monotherapy for IgG4-related disease-like features caused by idiopathic multicentric Castleman's disease: a case-based review.
A 68-year-old woman presented with dyspnea associated with a recurrent laryngeal tumor, pulmonary consolidation, mediastinal and axillary lymphadenopathy, sclerosing mesenteritis, and retroperitoneal fibrosis.
Disentangling direct and weight-mediated effects of physical activity on health-related quality of life in a 12-month real-world digital lifestyle intervention.
This longitudinal study examined physical activity and health-related quality of life (HRQoL) among 1,732 people participating in a 12-month digital lifestyle program; the abstract identifies it as a clinical trial but…
Translational applications and clinical utility of organoids in ovarian cancer: a systematic review.
This systematic review synthesized 13 studies of patient-derived organoids (PDOs) in ovarian cancer, assessing feasibility, histological fidelity, and agreement between organoid drug sensitivity and clinical outcomes.
Effects of transcranial direct current stimulation on nicotine use disorder: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed transcranial direct current stimulation (tDCS) for smoking-related outcomes in people with nicotine use disorder.
Impact of remote management using patient-reported outcomes on pain and anxiety after breast biopsy: the BIO-PSY randomized controlled trial.
The BIO-PSY French, single-centre, open-label randomised controlled trial assessed whether remote patient-reported outcome (PRO) monitoring with tailored interventions improved pain and anxiety after breast biopsy.
Anbalcabtagene autoleucel (PD-1 and TIGIT knockdown CD19 CAR T-cell therapy) for relapsed or refractory LBCL: the CRC01-01 trial.
The multicenter phase 1/2 CRC01-01 trial evaluated anbalcabtagene autoleucel, a CD19 CAR T-cell therapy with PD-1 and TIGIT knockdown, in patients with relapsed or refractory large B-cell lymphoma.
Silver diamine fluoride versus conventional restorative treatment for dental caries in primary teeth of children: a meta-analysis.
This meta-analysis compared 30% to 38% silver diamine fluoride (SDF) with conventional restorative approaches for caries control in children with carious primary teeth.
Administration-order effects in head-to-head comparisons of the EQ-5D-3L and EQ-5D-5L descriptive systems: evidence from a randomised general-population panel in Great Britain.
This randomised study in a general-population panel in Great Britain examined whether administration order affects comparisons of the EQ-5D-3L and EQ-5D-5L.
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