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2000 articles

October 202624

Case ReportMedical GeneticsOpen access

Severe growth retardation in Dent disease: a case report of a novel OCRL variant.

A 12-year-old boy with marked short stature and poor weight gain had low-molecular-weight proteinuria, haematuria, hypercalciuria and bilateral nephrocalcinosis, with normal renal function and no relevant family…

CEN Case RepOct 14, 2026Read case
Clinical ResearchAnesthesiologyOpen access

Perineural versus intravenous dexmedetomidine as an adjuvant for ilioinguinal/iliohypogastric nerve block in open inguinal hernia repair: a randomised controlled trial.

This single-centre, triple-blind randomised controlled trial compared perineural, intravenous and placebo dexmedetomidine as adjuncts to an ilioinguinal/iliohypogastric nerve block in 90 adults undergoing elective open…

HerniaOct 14, 2026Read summary
Case ReportAnesthesiology

Low-Volume Superior Trunk and Superficial Cervical Plexus Block With Sedation as the Sole Regional Anesthetic for Proximal Humerus Fracture Fixation in a Patient With Alzheimer Disease.

A 68-year-old woman with Alzheimer disease underwent fixation of a closed right proximal humerus fracture through a deltopectoral approach.

Am J Case RepOct 14, 2026Read case
Clinical ResearchCardiologyOpen access

Ramadan Fasting in Chronic Heart Failure: A Systematic Review.

This systematic review assessed clinical studies of Ramadan fasting in people with chronic heart failure. Searches of PubMed, Scopus, and Web of Science identified seven eligible studies from 137 records; most were…

Curr Cardiol RepOct 14, 2026Read summary
Case ReportAnesthesiology

Preoperative Sedation via Cecostomy Tube in an Autistic Adolescent: A Case Report.

A 13-year-old autistic boy with a preexisting cecostomy tube for chronic constipation had previously been unable to tolerate oral or intramuscular preoperative sedation because of agitation and physical aggression.

A A PractOct 14, 2026Read case
Case ReportDermatologyOpen access

Exploring the landscape of flagellate erythema as a rare cutaneous symptom of idiopathic inflammatory myopathy: a case series-based review.

Two patients with idiopathic inflammatory myopathy developed zebra-like flagellate erythema: one had immune-mediated necrotising myopathy and the other anti-Mi-2-positive cancer-associated myositis.

Rheumatol IntOct 14, 2026Read case
Clinical ResearchOncology (Medical)

Dietary and lifestyle quality and endometrial cancer: Incidence and survivorship outcomes-An umbrella review of systematic reviews and meta-analyses.

This umbrella review of 21 systematic reviews, including meta-analyses, assessed composite diet and lifestyle quality in relation to endometrial cancer (EC) risk and survivorship outcomes.

PLoS OneOct 14, 2026Read summary
Case ReportOncology (Medical)

Early extracranial dissemination with prolonged survival in IDH-wildtype glioblastoma: case study and comprehensive literature review.

A 65-year-old woman with IDH-wildtype, MGMT-methylated glioblastoma presented with seizures, right hemiplegia, and expressive aphasia.

CNS OncolOct 14, 2026Read case
Case ReportCardiology

Case Report: Veno-Arteriovenous Extracorporeal Membrane Oxygenation for Management of Pheochromocytoma-Induced Cardiac Arrest in a Post-Partum Patient.

A 34-year-old woman, two days postpartum, was admitted to intensive care with hypertensive crisis and respiratory failure. CT showed an 18-cm left adrenal mass suspicious for pheochromocytoma.

A A PractOct 14, 2026Read case
Case ReportPhysical Medicine & RehabilitationOpen access

Surgery to treat autonomic dysreflexia due to cubital tunnel syndrome in cervical spinal cord injury: a case report.

A 74-year-old woman with remote C6 spinal cord injury (AIS B) developed recurrent autonomic dysreflexia episodes that had not responded to standard measures.

Spinal Cord Ser CasesOct 14, 2026Read case
Clinical ResearchPsychiatry

An Internet-Based Cognitive-Behavioral Program, With Telephone Support, Improves Pain, Disability and Emotional Well-Being in Adults With Chronic Pain: Randomized Controlled Trial of the Pain Course With 2-Year Follow-Up.

This randomised controlled trial evaluated an internet-delivered, cognitive-behavioral Pain Course with clinician support in adults with chronic pain living in Ireland.

Clin J PainOct 14, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Characterizing vaginal misoprostol induction in individuals with and without severe obesity.

This secondary analysis of the vaginal misoprostol arm of a cluster-randomized trial compared term inductions in individuals with BMI < 40 versus ≥ 40 kg/m².

J Matern Fetal Neonatal MedOct 14, 2026Read summary
Clinical ResearchPhysical Medicine & RehabilitationOpen access

Clinical outcomes of low versus high intensity laser therapy in patients with subacute carpal tunnel syndrome: A randomized, single-blinded, controlled trial.

This single-blinded randomized controlled trial compared high-intensity laser therapy (HILT), low-level laser therapy (LLLT), and sham laser, each alongside physiotherapy, in 69 people with electromyography- and…

Lasers Med SciOct 14, 2026Read summary
Clinical ResearchNephrology

Intermittent or Continuous Renal-Replacement Therapy in Acute Kidney Injury.

This multicenter, open-label, randomized noninferiority trial compared intermittent hemodialysis with continuous renal-replacement therapy as initial treatment in critically ill adults with acute kidney injury and…

N Engl J MedOct 14, 2026Read summary
Clinical ResearchDermatology

Fecal microbiota transplantation for the treatment of neurogenic rosacea: protocol of a randomized, blinded, placebo-controlled explorer study.

This publication describes the protocol for a single-center, randomized, double-blind, placebo-controlled exploratory trial of fecal microbiota transplantation (FMT) in patients with neurogenic rosacea, a phenotype…

Ann MedOct 14, 2026Read summary
Clinical ResearchEndocrinology

Continuous Glucose Monitoring in Non-Insulin-Treated Type 2 Diabetes.

This 26-week, multicenter randomized trial compared continuous glucose monitoring (CGM) with routine care in adults with type 2 diabetes not using insulin at 22 US primary care practices.

N Engl J MedOct 14, 2026Read summary
Case ReportOncology (Medical)

Recurrent Primary Angiosarcoma of the Breast: Challenges and Pitfalls in a Case Report.

A patient presented with a breast lesion and skin involvement; histopathology and immunohistochemistry confirmed low- to intermediate-grade primary breast angiosarcoma.

Ann Ital ChirOct 14, 2026Read case
Case ReportNeurosurgery

Painless Spontaneous Spinal Epidural Hematoma Mimicking Acute Ischemic Stroke: A Case Report.

A woman in her early 60s receiving anticoagulant and antiplatelet therapy developed neck tightness and numbness in both limbs without pain, followed by transient right hemiplegia and rapid neurological deterioration.

Ann Ital ChirOct 14, 2026Read case
Clinical ResearchOncology (Medical)Open access

Volumetric discordance between ¹⁸F-FET-PET/MRI and MRI-based radiotherapy target volumes in high-grade glioma: a prospective pilot study (FETSMaRT).

This prospective pilot study enrolled 30 patients with WHO grade 3 or 4 high-grade glioma receiving postoperative radiotherapy.

J NeurooncolOct 14, 2026Read summary
Clinical ResearchAnesthesiologyOpen access

Effect of a Subanesthetic Dose of Esketamine on Postoperative Sleep Disturbance After Oocyte Retrieval Under Intravenous Anesthesia: A Randomized Controlled Trial.

This randomized, double-blind, placebo-controlled trial assessed whether intravenous esketamine reduces postoperative sleep disturbance (PSD) in women undergoing oocyte retrieval with intravenous anesthesia.

Drug Des Devel TherOct 14, 2026Read summary
Clinical ResearchPlastic Surgery

Multiple-Staged Versus Single-Stage Surgical Excision for the Reconstruction of Congenital Melanocytic Nevi: A Meta-Analysis of Efficacy and Safety.

This meta-analysis compared multiple-staged with single-stage excision and reconstruction for congenital melanocytic nevi (CMN). It pooled seven retrospective cohort or clinical controlled studies involving 578 patients.

Ann Ital ChirOct 14, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Immune biomarkers of response and resistance to ipilimumab and nivolumab in metastatic castration-resistant prostate cancer.

The multicenter phase II AMADEUS prostate expansion cohort evaluated escalating ipilimumab doses with nivolumab in 32 patients with metastatic castration-resistant prostate cancer, assessing disease control, tumoral CD8…

Sci AdvOct 14, 2026Read summary
Clinical ResearchGeneral Surgery

Modified LIFT via a Lateral Approach Versus Standard LIFT for Transsphincteric Anal Fistula: A Prospective Randomized Study.

This single-center prospective randomized study compared modified ligation of the intersphincteric fistula tract (LIFT) via a lateral approach with standard LIFT in adults with MRI-confirmed transsphincteric anal…

Ann Ital ChirOct 14, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Anxiety in patients with cancer and emergency department use: a systematic review.

This systematic review examined whether anxiety is associated with subsequent emergency department (ED) use among adults with cancer.

Support Care CancerOct 14, 2026Read summary

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