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2000 articles
October 202624
METALLIC RETINAL ARTERY EMBOLUS AFTER PIPELINE EMBOLIZATION DEVICE.
A 41-year-old woman who had undergone two Pipeline embolization device procedures for a left ophthalmic artery aneurysm was referred after an incidental refractile object was seen in the left macula.
Impact of Intermittent Preventive Treatment for Malaria in Pregnancy With Sulfadoxine-Pyrimethamine, Dihydroartemisinin-Piperaquine, and Their Combination on Infant Outcomes: A Randomized Controlled Trial.
This double-blind randomized controlled trial compared infant malaria and growth outcomes after maternal intermittent preventive treatment in pregnancy with sulfadoxine-pyrimethamine (SP), dihydroartemisinin-piperaquine…
Acute pericarditis caused by Kocuria kristinae with successful withdrawal from hemodialysis: a case report.
A 47-year-old man developed dialysis-dependent acute kidney injury after severe heatstroke. About a month later, imaging showed a marked increase in cardiothoracic ratio, and echocardiography demonstrated a substantial…
A NETwork meta-analysis with COST-effectiveness evaluation of pharmacological treatments for heart failure with reduced ejection fraction: NET-COST-HFrEF.
This network meta-analysis of 47 randomized controlled trials involving 75,978 patients with heart failure with reduced ejection fraction assessed guideline-directed drug combinations and their cost-effectiveness.
Effect of photobiomodulation on recovery from oral soft tissue local anaesthesia in paediatric patients: a preliminary split-mouth randomized clinical trial.
This preliminary split-mouth randomized clinical trial assessed whether 810-nm diode laser photobiomodulation (PBM) shortened oral soft-tissue anaesthesia after infiltration local anaesthesia in 34 children aged 8–12…
A missense variant in LAMB3 underlies variable expressivity in familial tooth agenesis and microdontia.
A three-generation family presented with non-syndromic dental anomalies, including missing teeth (oligodontia), microdontia and delayed eruption.
Changes in gait function associated with cerebral small vessel disease-related cognitive impairment during dual-task walking: a systematic review and meta-analysis.
This systematic review and meta-analysis examined whether dual-task (DT) gait measures distinguish people with cerebral small vessel disease-related cognitive impairment (CSVD-CI) from cognitively unimpaired controls…
Pearls & Oy-sters: Beyond the Bone Marrow-VEXAS Syndrome Presenting as Subacute Encephalomyelitis.
A 70-year-old man with myelodysplastic syndrome and confirmed VEXAS syndrome (UBA1 p.Met41Thr) developed subacute ascending paresthesia, Lhermitte sign, and urinary hesitancy.
TENON CAPSULE GRAFT AS A SEALANT IN PEDIATRIC RETINAL DETACHMENT.
The report describes four pediatric cases of complex retinal detachment associated with infantile high-myopic macular holes, Morning Glory Syndrome, or optic disk pit maculopathy.
A randomised controlled crossover trial comparing two mandibular repositioning appliances for treatment of moderate obstructive sleep apnoea.
This single-centre, randomised two-period crossover trial compared two custom-made mandibular repositioning appliances in 16 adults with moderate obstructive sleep apnoea.
Peritoneal Tuberculosis and Chronic Myeloid Leukaemia: A Case of Hickam's Dictum.
A 34-year-old man presented with persistent fever, ascites, thrombocytosis and clinical deterioration despite broad-spectrum therapy.
Comparative Effectiveness of Digital Exercise-Based Interventions for Improving Balance in Older Adults: Systematic Review and Network Meta-Analysis With GRADE Certainty of Evidence.
This systematic review and network meta-analysis compared five digital exercise-based approaches with conventional exercise (CE) and no treatment (NT) for balance in older adults.
Targeted BRAF /MEK inhibition as a salvage therapy for patients with metastatic melanoma harboring a BRAF L597R mutation: two case reports and review of the literature.
Two patients with metastatic melanoma harboring the BRAF L597R mutation had rapid clinical deterioration and disease progression after dual immune checkpoint inhibition.
Efficacy and Safety of Ushaq Capsule as Adjunctive Therapy in Patients With Lumbar Radiculopathy: A Double-Blind, Randomized, Placebo-Controlled Clinical Trial at Imam Khomeini Hospital, Tehran, Iran.
This double-blind, randomized, placebo-controlled trial evaluated Ushaq capsules as adjunctive therapy in 68 patients with lumbar radiculopathy.
Catheter ablation in end-stage heart failure with atrial fibrillation: an hierarchical endpoint analysis of the CASTLE-HTx trial.
This ancillary hierarchical endpoint analysis of the multicentre randomized CASTLE-HTx trial compared catheter ablation plus guideline-directed medical therapy (GDMT) with medical therapy alone in 194 patients with…
Comparison of sterile silicone studs and scalp infiltration with lignocaine for the attenuation of the hemodynamic and stress response to skull pin insertion during craniotomy in pediatric neurosurgical patients: a randomized controlled trial : Sterile silicone studs versus lignocaine infiltration for skull pin insertion.
This randomized controlled trial compared sterile silicone studs (SSS) with lignocaine infiltration for skull pin insertion in 64 children aged 12 years or younger undergoing neurosurgery.
Breastfeeding and maternal bone health 10 years postpartum: findings from the ROLO longitudinal cohort study.
This longitudinal cohort analysis examined whether breastfeeding behaviours were associated with maternal bone health 10 years after pregnancy.
Controlled postoperative red wine intake versus abstinence in habitual wine drinkers undergoing elective urological surgery (WISE): a translational randomized controlled trial assessing quality of life, surgical outcomes and complications.
This single-center randomized controlled trial compared postoperative abstinence with standardized red wine intake in habitual wine drinkers undergoing elective urological surgery.
Dengue virus controlled human challenge reveals that preexisting immunity shapes viral replication and broadly protective responses.
This phase 1 controlled human challenge trial enrolled 45 healthy adults to examine how preexisting immunity shapes responses to heterotypic dengue virus challenge.
Familial Glioma in a Father and Son: Integrated Genomic and Multi-compartment Proteomic Profiling.
A 60-year-old father and his 35-year-old son presented with gliomas. The father’s tumor was glioblastoma, IDH-wildtype, WHO grade 4, with an unmethylated MGMT promoter; the son’s was astrocytoma, IDH-mutant, WHO grade…
Parathyroid Hormone-related Peptide Is a Better Indicator of Cancer Treatment Efficacy Than Serum Calcium.
A 66-year-old woman with extensive cutaneous squamous cell carcinoma of the scalp, unsuitable for primary surgical removal, received cemiplimab.
Postoperative Pain Treatment After Pancreatic Surgery: A Systematic Review With Meta-Analyses and Trial Sequential Analyses.
This PROSPERO-registered systematic review and meta-analysis examined postoperative analgesia after total pancreatectomy, pancreaticoduodenectomy, and distal pancreatectomy.
Real-Time Electronic Patient-Reported Outcome Monitoring With Digital Triage and Care-Team Integration in Early Breast Cancer: ENABLE Randomized Controlled Trial.
The multicenter, open-label ENABLE randomized controlled trial compared weekly electronic patient-reported outcome (ePRO) screening with rule-based triage and care-team alerts against an active app-based support…
BILATERAL PARACENTRAL ACUTE MIDDLE MACULOPATHY IN A PEDIATRIC PATIENT WITH SICKLE CELL DISEASE.
An 8-year-old boy with HbSS sickle cell disease and no previous sickle cell retinopathy developed blurred vision, headache, photopsia, and metamorphopsia during an influenza A-associated upper respiratory illness.
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