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2000 articles
October 202624
Survival Outcomes in Metastatic Colorectal Cancer Patients with BRAF Mutations Undergoing Targeted Chemotherapy: A Reconstructed Individual Patient Data Meta-Analysis of Randomized Controlled Trials.
This reconstructed individual patient-data meta-analysis of 18 randomized controlled trials examined survival outcomes across targeted treatment classes in BRAF V600E-mutant metastatic colorectal cancer.
Haemodialysis in haemophilia B: a case report. Challenges and strategies from a nephrology perspective.
A 68-year-old man with severe haemophilia B and kidney failure required kidney replacement therapy. He received prophylactic Idelvion® (albutrepenonacog alfa), then underwent arteriovenous fistula creation and started…
Treatment Procedures for the Edentulous Maxilla: Supplement Report for the First Global Consensus for Clinical Guidelines (GCCG).
The report describes clinical rehabilitation of an edentulous maxilla using implant-supported restorations. It applies the treatment-procedures component of the First Global Consensus for Clinical Guidelines (GCCG)…
Conservative management of disseminated intravascular coagulation caused by uterine leiomyoma degeneration in pregnancy: Case report and review.
A 35-year-old woman at 25 weeks’ gestation presented with lower abdominal pain and a tender 6.5 cm uterine leiomyoma; fetal well-being and placental appearance were normal on ultrasonography.
Association of Helicobacter pylori eradication with proteinuria reduction and kidney outcomes: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed whether Helicobacter pylori eradication is associated with renal benefits in people with kidney disease or proteinuria.
Integrated management of uterine prolapse during pregnancy: Case report and literature review of successful term delivery following cervical cerclage and pessary utilization.
A 43-year-old woman with recurrent pregnancy losses, including a second-trimester loss attributed to cervical incompetence, presented at 11 weeks’ gestation with stage III uterine prolapse.
Polycystic ovary syndrome research in sub-Saharan Africa: a systematic review on current status and future directions.
This systematic review assessed original research on polycystic ovary syndrome (PCOS) in sub-Saharan African populations, searching four databases through 9 August 2026.
Prehospital Analgesia in Trauma: A Systematic Review of Current Evidence.
This systematic review assessed the safety and effectiveness of pharmacologic analgesia given before hospital arrival to acutely injured adults aged over 15 years.
Robot-assisted minimally invasive versus conventional open transforaminal lumbar interbody fusion for lumbar degenerative disease: a prospective randomized controlled trial.
This prospective, single-centre, assessor-blinded randomized trial compared robot-assisted minimally invasive TLIF with conventional fluoroscopy-guided open TLIF in 128 patients with lumbar degenerative disease.
Expanding the molecular and phenotypic spectrum of MMP2-related multicentric osteolysis, nodulosis, and arthropathy: two brothers with marked intrafamilial variability and a review of the literature.
Two brothers, aged 14 and 8 years, from a consanguineous family had molecularly confirmed MMP2-related multicentric osteolysis, nodulosis, and arthropathy (MONA), with the same homozygous c.1648 C > T (p.Arg550Ter)…
The Effects of Mind-Body Exercise on Cognitive Function and Peripheral Blood BDNF in Elderly People With Mild Cognitive Impairment: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis pooled 17 randomized controlled trials involving 1,251 older adults with mild cognitive impairment to assess mind-body exercise and cognition and peripheral blood BDNF.
Community Health Worker Interventions Addressing Social Determinants of Health in Chronic Disease: A Systematic Review.
This systematic review assessed US randomized and quasi-experimental studies of patient-facing community health worker (CHW) interventions addressing at least one social determinant of health among adults with chronic…
Vertebral fractures in a young woman: the impact of hypogonadism, glucocorticoids, and chronic disease.
A premenopausal woman developed painful vertebral fractures while receiving prednisolone for newly diagnosed systemic lupus erythematosus.
Levodopa or dopamine agonists for enhancing motor function after stroke.
This Cochrane systematic review and meta-analysis assessed whether levodopa or dopamine agonists improve motor function after stroke.
Is plant-based protein supplementation as effective as whey protein? A systematic review and meta-analysis in untrained adults undergoing resistance training.
This systematic review and meta-analysis compared plant-based with whey protein supplementation for body composition in untrained adults aged 18–59 years undertaking resistance training.
Effect of nutrition counseling on complementary feeding practices among mothers with children aged 6-23 months in West Gojjam Zone, Northwest Ethiopia: A cluster-randomized controlled trial.
This two-arm, parallel cluster-randomized controlled trial assessed Health Belief Model-based nutrition counseling for mothers of children aged 6–23 months in rural West Gojjam Zone, Northwest Ethiopia.
Resting-State Functional MRI and Clinical Outcomes After Acute Disorders of Consciousness: A Systematic Review.
This systematic review examined whether resting-state functional MRI (rs-fMRI) measures during the acute phase of severe brain injury are associated with outcomes in adults with disorders of consciousness.
High-intensity focused ultrasound as a bridging vascular-modulating therapy for fertility-sparing management of placental site trophoblastic tumor complicated by uterine arteriovenous fistula: a case report.
A 23-year-old woman had persistently plateaued serum human chorionic gonadotropin after hysteroscopic management for suspected incomplete abortion.
Characteristics of treatment responses to physical exercise and diet in diabetic peripheral artery disease patients: a systematic review.
This systematic review examined human studies of exercise and diet in people with diabetic peripheral artery disease (PAD). Of 18 included studies, 15 assessed exercise and three examined diet.
Effect of fasting and postprandial states on thyroid function test parameters and diagnostic interpretation: A systematic review and meta-analysis.
This systematic review and meta-analysis assessed whether fasting versus postprandial sampling affects thyroid function tests and diagnostic classification.
A 61-Year-Old Woman With Locally Advanced Pancreatic Adenocarcinoma Managed With Neoadjuvant FOLFIRINOX, Total Pancreatectomy, Splenectomy, Portal Vein and Common Hepatic Artery Resection, and Combined Vascular Reconstruction Using Splenic Artery Transposition: A Case Report.
A 61-year-old woman presented with progressive jaundice and CA 19-9 of 210 U/mL. Biopsy confirmed pancreatic ductal adenocarcinoma, and imaging showed portal vein and common hepatic artery involvement without distant…
Cutaneous clues: Malignant acanthosis nigricans and tripe palms as first signs of recurrent endometrial carcinoma.
A 73-year-old woman, disease-free for six years after treatment of stage IB endometrial endometrioid adenocarcinoma, developed acanthosis nigricans and tripe palms.
Secondary Syphilis.
A 46-year-old man presented with two months of progressive, painful visual loss. Examination showed bilateral panuveitis alongside widespread ulcerative skin lesions and alopecia.
Hypothalamic Neurochemical and Microglial Suppression in Long-Standing Human Hibernation-Like Syndrome.
A 57-year-old woman had a more than 30-year history of winter-associated hypothermia, neuroendocrine instability, psychomotor suppression and circannual rhythmicity.
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