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2000 articles
October 202624
Curative-intent management of de novo metastatic nasopharyngeal carcinoma: an evidence-based consensus guideline from the International Collaborating Oncology Organisations.
This international consensus guideline addresses curative-intent management of de novo metastatic nasopharyngeal carcinoma, a population historically treated with palliative intent.
From Daily Attitudes to Alcohol-Related Harm: A Within-Person Serial Mediation Test Informed by the Theory of Planned Behavior.
This multilevel daily-diary study examined whether day-to-day changes in attitudes toward heavy drinking were linked to alcohol-related harm through intentions and consumption.
Efficacy of High-Frequency Transcranial Magnetic Stimulation Therapy for Depression With Insomnia Symptoms: A Systematic Review and Meta-Analysis Based on Randomized Controlled Trials.
This systematic review and meta-analysis of randomized controlled trials assessed left dorsolateral prefrontal cortex-targeted high-frequency repetitive transcranial magnetic stimulation (HF-rTMS) for people with…
A rare cause of postpartum hemoperitoneum: Uterine laceration secondary to sustained transabdominal uterine massage following vaginal delivery: A case report.
After vaginal delivery, a patient with an unscarred uterus developed postpartum hemorrhage from uterine atony and was treated with uterotonics and transabdominal uterine massage.
Short-term effects of myofascial release with therapist-mediated transcutaneous electrical nerve stimulation in adolescent idiopathic scoliosis: an exploratory randomized controlled trial .
This assessor-blinded, exploratory randomized controlled trial evaluated short-term myofascial release with therapist-mediated transcutaneous electrical nerve stimulation (MFR-TENS) in 27 adolescents with idiopathic…
A missense variant in LAMB3 underlies variable expressivity in familial tooth agenesis and microdontia.
A three-generation family presented with non-syndromic dental anomalies, including missing teeth (oligodontia), microdontia and delayed eruption.
Mind Your Heart-A Web-Based Dietary Approaches to Stop Hypertension Diet and Mindful Eating Intervention for Working Adults at Elevated Cardiovascular Risk: Pilot Randomized Controlled Trial.
This pilot randomized controlled trial assessed the feasibility and preliminary effects of a six-week, self-guided web-based DASH education program, with or without mindful eating instruction, among working adults at…
METALLIC RETINAL ARTERY EMBOLUS AFTER PIPELINE EMBOLIZATION DEVICE.
A 41-year-old woman who had undergone two Pipeline embolization device procedures for a left ophthalmic artery aneurysm was referred after an incidental refractile object was seen in the left macula.
TENON CAPSULE GRAFT AS A SEALANT IN PEDIATRIC RETINAL DETACHMENT.
The report describes four pediatric cases of complex retinal detachment associated with infantile high-myopic macular holes, Morning Glory Syndrome, or optic disk pit maculopathy.
WHIPLASH MACULOPATHY: STRUCTURAL SEQUELAE AND THE CORRESPONDING VISUAL IMPAIRMENT, DOCUMENTED WITH OPTICAL COHERENCE TOMOGRAPHY.
A 55-year-old woman developed reduced vision in her left eye after a head-on collision. Examination showed subtle retinal pigment epithelium disruption; OCT demonstrated neurosensory detachment and intraretinal cysts.
B cell subsets are associated with durable responses in distinct cancer types after immune checkpoint inhibition.
This study examined B-cell responses and outcomes after immune checkpoint inhibition, combining a prospective randomized phase 2 trial of 106 patients with single-cell profiling of intratumoral B cells from 152 patients…
Controlled postoperative red wine intake versus abstinence in habitual wine drinkers undergoing elective urological surgery (WISE): a translational randomized controlled trial assessing quality of life, surgical outcomes and complications.
This single-center randomized controlled trial compared postoperative abstinence with standardized red wine intake in habitual wine drinkers undergoing elective urological surgery.
OPTIC DISK PIT: A TRIGGER FOR SECONDARY MULTIPLE EVANESCENT WHITE DOT SYNDROME.
A 41-year-old man with a right optic disk pit presented with right-eye visual loss and photopsia; visual acuity was 20/100.
Effect of vutrisiran on components of health status in transthyretin amyloidosis with cardiomyopathy: the HELIOS-B study.
This analysis of HELIOS-B, a double-blind, randomized, placebo-controlled trial, examined individual health-status components in patients with transthyretin amyloidosis with cardiomyopathy (ATTR-CM).
HYDROXYCHLOROQUINE TOXICITY WITH SHORT DURATION OF HYDROXYCHLOROQUINE USE AND UNILATERAL BULL's EYE MACULOPATHY.
A 77-year-old Japanese woman presented with years of gradually worsening vision in her right eye. She had rheumatoid arthritis and had taken hydroxychloroquine 200 mg for five years, approximately 20 years earlier.
Obesity and perioperative outcomes of robotic-assisted surgery for endometrial cancer: a systematic review and meta-analysis.
This systematic review and meta-analysis compared perioperative outcomes after robotic-assisted surgery for endometrial cancer in patients classified as obese or non-obese by the original studies.
Changes in gait function associated with cerebral small vessel disease-related cognitive impairment during dual-task walking: a systematic review and meta-analysis.
This systematic review and meta-analysis examined whether dual-task (DT) gait measures distinguish people with cerebral small vessel disease-related cognitive impairment (CSVD-CI) from cognitively unimpaired controls…
MACULAR CHOROIDAL NEOVASCULARIZATION IN PERIPAPILLARY HYPERREFLECTIVE OVOID MASS-LIKE STRUCTURES: CASE REPORT.
A healthy 36-year-old woman presented with three days of vision loss in her right eye. Optical coherence tomography of the optic nerve head showed peripapillary hyperreflective ovoid mass-like structures (PHOMS), while…
Immunogenicity and Safety of Coadministration of AS01E-Adjuvanted Respiratory Syncytial Virus Prefusion F Protein Vaccine and a COVID-19 mRNA Vaccine in Adult s Aged ≥50 Years: A Phase 3, Randomized, Noninferiority Trial.
This phase 3, open-label, multicenter randomized noninferiority trial compared coadministration of an AS01E-adjuvanted RSV prefusion F vaccine and an Omicron XBB.1.5 COVID-19 mRNA vaccine with administration…
Efficacy and Safety of Ushaq Capsule as Adjunctive Therapy in Patients With Lumbar Radiculopathy: A Double-Blind, Randomized, Placebo-Controlled Clinical Trial at Imam Khomeini Hospital, Tehran, Iran.
This double-blind, randomized, placebo-controlled trial evaluated Ushaq capsules as adjunctive therapy in 68 patients with lumbar radiculopathy.
Pearls & Oy-sters: Beyond the Bone Marrow-VEXAS Syndrome Presenting as Subacute Encephalomyelitis.
A 70-year-old man with myelodysplastic syndrome and confirmed VEXAS syndrome (UBA1 p.Met41Thr) developed subacute ascending paresthesia, Lhermitte sign, and urinary hesitancy.
Dengue virus controlled human challenge reveals that preexisting immunity shapes viral replication and broadly protective responses.
This phase 1 controlled human challenge trial enrolled 45 healthy adults to examine how preexisting immunity shapes responses to heterotypic dengue virus challenge.
Robot-assisted versus conventional cranial stereotactic neurosurgery: a systematic review and meta-analysis of targeting accuracy, procedural efficiency, and safety.
This systematic review and meta-analysis compared robot-assisted with conventional cranial stereotactic neurosurgery across 21 comparative studies, examining targeting accuracy, procedural efficiency, safety and…
VITREOUS METASTASIS OF LARYNGEAL CARCINOMA PRESENTING AS A WHITE MASS: A CASE REPORT.
A 56-year-old man receiving immunochemotherapy for laryngeal carcinoma presented with two weeks of left-eye photopsia. Examination showed mild anterior chamber and vitreous cells, slight macular edema, and a white…
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