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1502 articles

October 202624

Clinical ResearchNeurologyOpen access

Symptom improvement with dosing above 9 g of low-sodium oxybate: effectiveness and safety in participants with narcolepsy in the DUET study.

This prospective, multicohort, open-label study evaluated effectiveness and safety of low-sodium oxybate (LXB) doses above 9 g/night in participants with narcolepsy type 1 or 2 who were already taking 9 g/night.

J Clin Sleep MedOct 15, 2026Read summary
Clinical ResearchCardiology

Efficacy and Safety of Enlicitide in Hypercholesterolemia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

This systematic review and random-effects meta-analysis assessed efficacy and safety of oral enlicitide in adults with hypercholesterolemia.

Endocrinol Diabetes MetabOct 14, 2026Read summary
Clinical ResearchGastroenterology

Safety, Tolerability and Antiviral Activity of GST-HG131 in Chronic Hepatitis B: A Randomized, Double-Blind Phase IIa Study.

This randomized, double-blind, placebo-controlled Phase IIa trial assessed oral GST-HG131 in 45 adults with chronic hepatitis B receiving nucleos(t)ide analogue monotherapy.

Liver IntOct 14, 2026Read summary
Clinical ResearchPsychiatry

The psychological experience of body image change in adult stoma patients: A systematic review and qualitative meta-synthesis.

This systematic review and qualitative meta-ethnography synthesised English-language qualitative research on body image change in adults with a stoma. Eighteen studies involving 602 participants were included.

Br J Health PsycholOct 14, 2026Read summary
Clinical ResearchPsychiatry

An Internet-Based Cognitive-Behavioral Program, With Telephone Support, Improves Pain, Disability and Emotional Well-Being in Adults With Chronic Pain: Randomized Controlled Trial of the Pain Course With 2-Year Follow-Up.

This randomised controlled trial evaluated an internet-delivered, cognitive-behavioral Pain Course with clinician support in adults with chronic pain living in Ireland.

Clin J PainOct 14, 2026Read summary
Clinical ResearchAnesthesiology

Pericapsular Nerve Group Block Versus Femoral Nerve Block for Analgesia in Newly Admitted Patients With Hip Fractures: A Randomized Controlled Trial.

This randomized controlled trial compared preoperative pericapsular nerve group (PENG) block with femoral nerve block (FNB) in 60 newly admitted patients with hip fractures.

Clin J PainOct 14, 2026Read summary
Clinical ResearchGeriatrics

Vegetarian and Vegan Diets and the Risk of Hip Fracture in Adults: A Systematic Review and Meta-analysis.

This systematic review and meta-analysis assessed hip-fracture risk in adults following vegetarian or vegan diets compared with meat-eaters. Four cohort studies involving 529 672 participants were included.

Nutr RevOct 14, 2026Read summary
Clinical ResearchDermatology

The Use of Cannabidiol in Cutaneous Wound Healing: A Systematic Review.

This qualitative systematic review assessed cannabidiol (CBD) for cutaneous wound healing, including in vivo studies and clinical trials identified through searches of seven databases. Six studies were included.

FASEB JOct 14, 2026Read summary
Clinical ResearchPreventive Medicine / Public Health

A Single Exercise Session Elicits a Transient Kynurenine Metabolic Signature in Health and Disease: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis examined acute changes in circulating tryptophan (TRP) and kynurenine-pathway metabolites after a single exercise session.

FASEB JOct 14, 2026Read summary
Case ReportOncology (Medical)

Early extracranial dissemination with prolonged survival in IDH-wildtype glioblastoma: case study and comprehensive literature review.

A 65-year-old woman with IDH-wildtype, MGMT-methylated glioblastoma presented with seizures, right hemiplegia, and expressive aphasia.

CNS OncolOct 14, 2026Read case
Case ReportCardiology

Case Report: Veno-Arteriovenous Extracorporeal Membrane Oxygenation for Management of Pheochromocytoma-Induced Cardiac Arrest in a Post-Partum Patient.

A 34-year-old woman, two days postpartum, was admitted to intensive care with hypertensive crisis and respiratory failure. CT showed an 18-cm left adrenal mass suspicious for pheochromocytoma.

A A PractOct 14, 2026Read case
Case ReportAnesthesiology

Preoperative Sedation via Cecostomy Tube in an Autistic Adolescent: A Case Report.

A 13-year-old autistic boy with a preexisting cecostomy tube for chronic constipation had previously been unable to tolerate oral or intramuscular preoperative sedation because of agitation and physical aggression.

A A PractOct 14, 2026Read case
Clinical ResearchOncology (Medical)

Dietary and lifestyle quality and endometrial cancer: Incidence and survivorship outcomes-An umbrella review of systematic reviews and meta-analyses.

This umbrella review of 21 systematic reviews, including meta-analyses, assessed composite diet and lifestyle quality in relation to endometrial cancer (EC) risk and survivorship outcomes.

PLoS OneOct 14, 2026Read summary
Clinical ResearchCardiologyOpen access

Ramadan Fasting in Chronic Heart Failure: A Systematic Review.

This systematic review assessed clinical studies of Ramadan fasting in people with chronic heart failure. Searches of PubMed, Scopus, and Web of Science identified seven eligible studies from 137 records; most were…

Curr Cardiol RepOct 14, 2026Read summary
Case ReportMedical GeneticsOpen access

Severe growth retardation in Dent disease: a case report of a novel OCRL variant.

A 12-year-old boy with marked short stature and poor weight gain had low-molecular-weight proteinuria, haematuria, hypercalciuria and bilateral nephrocalcinosis, with normal renal function and no relevant family…

CEN Case RepOct 14, 2026Read case
Clinical ResearchOncology (Medical)Open access

A comprehensive review of European clinical practice guidelines on psychological and cognitive assessment and support for cancer patients and their families.

This systematic review mapped European clinical practice guidelines and recommendations published in the preceding 15 years on psychological and cognitive assessment and support for people with cancer and their…

Support Care CancerOct 14, 2026Read summary
Clinical ResearchAnesthesiologyOpen access

Perineural versus intravenous dexmedetomidine as an adjuvant for ilioinguinal/iliohypogastric nerve block in open inguinal hernia repair: a randomised controlled trial.

This single-centre, triple-blind randomised controlled trial compared perineural, intravenous and placebo dexmedetomidine as adjuncts to an ilioinguinal/iliohypogastric nerve block in 90 adults undergoing elective open…

HerniaOct 14, 2026Read summary
Case ReportDermatologyOpen access

Exploring the landscape of flagellate erythema as a rare cutaneous symptom of idiopathic inflammatory myopathy: a case series-based review.

Two patients with idiopathic inflammatory myopathy developed zebra-like flagellate erythema: one had immune-mediated necrotising myopathy and the other anti-Mi-2-positive cancer-associated myositis.

Rheumatol IntOct 14, 2026Read case
Case ReportCardiology

Integrated Use of Extracorporeal Membrane Oxygenation and Molecular Adsorbent Recirculating System for Refractory Cardiotoxic Ingestion: A Single-Center Case Series.

Five consecutive patients with severe calcium-channel blocker or beta-adrenergic antagonist ingestions developed profound hypotension and respiratory failure despite standard therapies.

Crit Care ExplorOct 14, 2026Read case
Clinical ResearchInfectious Diseases

Viral interference with SARS-CoV-2 during the COVID-19 pandemic: An individual participant data meta-analysis.

This individual participant data meta-analysis examined whether SARS-CoV-2 co-occurred with other respiratory viruses in ten cohort studies conducted during 2020–2024.

Epidemiol InfectOct 14, 2026Read summary
Case ReportCardiothoracic Surgery

Robotic selective thoracic sympathectomy for hyperhidrosis: refined technique and anatomical variation.

Primary hyperhidrosis substantially impairs quality of life. Conventional sympathectomy risks compensatory hyperhidrosis through trunk disruption, whilst selective sympathectomy preserves the trunk while dividing…

Multimed Man Cardiothorac SurgOct 14, 2026Read case
Case ReportCardiothoracic Surgery

Endoscopic secondary chordae transfer and edge-to-edge repair for the treatment of asymmetric anterior leaflet prolapse.

A 59-year-old patient with Barlow’s disease presented with severe mitral regurgitation from asymmetric anterior leaflet prolapse.

Multimed Man Cardiothorac SurgOct 14, 2026Read case
Clinical ResearchPsychiatry

Cortisol and cognition in psychotic disorders: A systematic review and multi-level meta-analysis.

This systematic review and three-level meta-analysis examined associations between cortisol and cognition in people with psychotic disorders.

Psychol MedOct 14, 2026Read summary
Clinical ResearchUrology

Prevalence of urinary incontinence among women in Turkey: A systematic review and meta-analysis.

This systematic review and meta-analysis estimated urinary incontinence (UI) prevalence among women in Türkiye. It included 45 studies published between 2005 and 2025, with 41,038 participants.

Afr J Reprod HealthOct 14, 2026Read summary

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