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1696 articles
September 202624
Masked polycythaemia vera presenting with extensive splanchnic venous thrombosis and mesenteric ischaemia.
A woman in her 60s with masked polycythaemia vera (PV) presented with extensive splanchnic venous thrombosis and mesenteric ischaemia after 5 years of management with phlebotomy and aspirin.
Marjolin's ulcer developing in a post-traumatic scar: management with negative pressure wound therapy and split-thickness skin grafting.
A man in his 60s presented with a large, non-healing ulcer at the site of a traumatic injury and reconstructive surgery from three decades prior.
Saprochaete pneumonia presenting as septic shock in an elderly patient with poorly controlled diabetes mellitus.
An elderly woman with poorly controlled diabetes presented with community-acquired pneumonia, septic shock, and multi-organ dysfunction. Despite initial antibiotic treatment, her condition deteriorated.
Metastatic muscle invasive bladder cancer in pregnancy.
A woman in her 30s presented during the second trimester with hematuria and left flank pain. MRI identified a T3b bladder tumor with suspected peritoneal invasion.
Anakinra versus intramuscular methylprednisolone acetate for gout flares in people with chronic kidney disease (ASGARD): a UK randomised multicentre, double-blind, double-dummy controlled feasibility study with economic, qualitative and safety assessment.
The ASGARD study was a feasibility randomized controlled trial comparing anakinra to intramuscular methylprednisolone acetate for treating gout flares in patients with chronic kidney disease.
Performing lifestyle changes and reducing stroke risk: a process evaluation of a stroke prevention intervention.
This randomized controlled trial evaluated a stroke prevention intervention in Swedish primary healthcare, focusing on implementation processes and mechanisms of change among 122 high-risk participants.
Effectiveness of psychosocial counselling on treatment adherence among patients with a new tuberculosis diagnosis in primary care: a study protocol for a cluster-randomised controlled trial.
This study protocol outlines a cluster-randomised controlled trial aimed at evaluating the effectiveness of psychosocial counselling on treatment adherence among newly diagnosed tuberculosis patients in primary care…
Implementing a medical opinion leader-led management model to promote timely treatment initiation among screen-positive patients with upper gastrointestinal cancer in rural China: a cluster randomised controlled trial protocol.
This cluster randomised controlled trial aims to assess the effectiveness of a medical opinion leader-led management model in reducing treatment initiation time for screen-positive upper gastrointestinal cancer patients…
Association between personal birth companion and maternal mental health in low- and middle-income countries: a systematic review.
This systematic review examined the impact of personal birth companions on maternal mental health during labor and postpartum in low- and middle-income countries.
Behavior Change and Compliance Outcomes of a Novel Web-Based Health Behavior Tool Integrated Into Certified Exercise Practitioner Services: Twelve-Week, Two-Arm, Randomized Pre-Post Trial.
This randomized controlled trial evaluated the impact of a web-based health behavior tool, the FESS questionnaire, on health behaviors in 41 older adults (median age 65) receiving services from certified exercise…
Knowledge Performance, User Experience, and Cybersickness With Immersive Virtual Reality for Tai Chi Movement-Encoding in Older Adults: Randomized Comparison Study.
This randomized controlled trial compared immersive virtual reality (VR) to 2D video instruction for Tai Chi movement-encoding in 106 community-dwelling older adults.
Clinical outcomes of hyaluronic acid-sorbitol injection in athletes with patellofemoral pain: Evaluation of the potential influence of body mass index.
This prospective clinical trial evaluated the effects of a single 4 mL hyaluronic acid-sorbitol injection on knee function in 60 athletes aged 30-55 with patellofemoral pain (PFP) over 6 months.
Open versus closed suctioning on lung volume and oxygenation in ARDS patients with PEEP 5-10 cmH2O: A randomized controlled trial.
This randomized controlled trial compared open suctioning (OS) and closed suctioning (CS) in 60 ARDS patients on mechanical ventilation with PEEP 5-10 cmH2O.
A high intensity vs. casual speed walking intervention to reverse frailty among older adults: a cluster randomized controlled trial.
This cluster-randomized controlled trial evaluated the effects of high-intensity walking (HIW) versus casual-speed walking (CSW) on frailty in 165 prefrail and frail adults aged ≥60 years.
Positive Syphilis Serology With Concurrent Disseminated Talaromycosis marneffei in a Patient With HIV: A Case Report.
A 37-year-old male with HIV presented with a rash and was initially diagnosed with secondary syphilis based on positive serology. After ampicillin treatment failed to improve his condition, he developed fever and cough.
The oral und systemic health risks of sugar consumption: an umbrella review.
This umbrella review analyzed systematic reviews to assess the health risks associated with free sugar consumption, focusing on both oral and systemic health.
Non-paraneoplastic Autoimmune Cerebellar Ataxia with Sensory Ataxia Associated with the Anti-Ca/ARHGAP26 Antibody: A Case Report.
A man in his 50s presented with one month of subacute, progressive gait instability, exhibiting both cerebellar and deep-sensory ataxia.
Comparative Effectiveness and Safety of FOLFOXIRI Plus Cetuximab Versus FOLFOXIRI Plus Bevacizumab in Metastatic Colorectal Cancer: A GRADE-assessed Systematic Review and Meta-analysis.
This systematic review and meta-analysis evaluated the effectiveness and safety of FOLFOXIRI plus cetuximab versus FOLFOXIRI plus bevacizumab in 561 patients with metastatic colorectal cancer (mCRC).
Operative treatment of high-grade medial collateral ligament injury and chronic medial knee instability: a systematic review.
This systematic review assessed the operative treatment of high-grade medial collateral ligament (MCL) injuries and chronic medial knee instability, focusing on clinical phenotype rather than MCL grade.
Supporting Caregivers Behind Youth with T1D: A Systematic Review of Psychosocial Interventions and Youth Glycemic Outcomes.
This systematic review analyzed 26 studies on psychosocial interventions for parents of children with Type 1 Diabetes (T1D) from 2019 to 2025.
Cardiac intimal sarcoma presenting with pseudo-pulmonary embolism: surgical debulking, RVOT reconstruction and pulmonary valve replacement.
A 27-year-old woman presented with dyspnoea and signs of right-heart failure following delivery. Initial imaging suggested pulmonary embolism, prompting emergency surgery due to haemodynamic instability.
Transverse infundibulotomy for resection of a right ventricular outflow tract myxoma.
A 25-year-old asymptomatic 64 kg female with an incidental heart murmur was found, on echocardiography, to have a 2 cm echogenic mass beneath the pulmonary valve, with a peak gradient of 11 mmHg and mild pulmonic…
Oral anticoagulant monotherapy versus oral anticoagulant plus antiplatelet therapy in adults with stable coronary artery disease.
This is a protocol for a Cochrane review (intervention). The objectives are as follows: To assess the benefits and harms of oral anticoagulant monotherapy compared with oral anticoagulant plus antiplatelet therapy in…
Laparoscopic Treatment of Zinner Syndrome: A Case Report.
A 36-year-old man presented with infertility and chronic pelvic pain, diagnosed with Zinner syndrome, which included left renal agenesis, ureteral atresia, and a large seminal vesicle cyst.
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