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1696 articles
September 202624
A rare case of hereditary spastic paraplegia with homozygous mutation in the ZFYVE26 gene.
A 19-year-old female with consanguineous parents presented with gait disturbances, lower limb spasticity, and dysarthria. Neurological examination revealed motor and mental retardation, bilateral lower limb spasticity…
The FIRE technique - A tube ligation alternative.
A patient undergoing glaucoma surgery with a nonvalved glaucoma drainage device (GDD) was treated using the Flanged Intraluminal Ripcord Element (FIRE) technique.
Autologous rotational partial thickness scleral flap - A salvage technique for late leaking blebs with scleral fistula.
Two patients with late leaking blebs complicated by scleral fistulae underwent a modified autologous rotational partial-thickness scleral flap procedure.
Effect of strengths-based, tiered, accessible resources and supports (STARS) for Kids project, a codesigned hybrid service delivery framework to identify and support child development, parent mental health and psychosocial needs among parents and carers of children aged 6 months to 3 years: a randomised controlled trial protocol.
This randomized controlled trial protocol evaluates the STARS for Kids model, designed to enhance early identification and support for child development and parental mental health among parents of children aged 6 months…
Sarcopenia in Indian adults with type 2 diabetes: a systematic review and meta-analysis of prevalence and associated factors.
This systematic review and meta-analysis assessed the prevalence of sarcopenia among Indian adults with type 2 diabetes mellitus (T2DM).
Lumbar spinal brucellosis presenting as an atypical epidural abscess.
A man in his 50s presented with low back pain and lower limb radiculopathy. MRI revealed a ventral epidural collection at L4-L5, resembling a sequestered disc fragment, without significant vertebral or disc involvement.
Uveitis as a class effect of Bruton tyrosine kinase inhibitors: ibrutinib and zanubrutinib ocular toxicity.
A man in his early 50s with Waldenström macroglobulinaemia developed posterior uveitis while on ibrutinib, characterized by vitreous and retinal infiltrates.
Autologous retinal transplant for macular hole in retinal detachment following bag-intraocular lens complex dislocation.
An elderly patient in their late 80s presented with total retinal detachment and a macular hole following pars plana vitrectomy for a dislocated capsular bag-intraocular lens complex.
Rotational thromboelastometry guided transfusion in venom-induced consumptive coagulopathy following a haemotoxic snakebite.
A woman in her 30s presented with severe haemotoxic snake envenoming and venom-induced consumptive coagulopathy (VICC), leading to early multiorgan involvement.
Recurrent serotonin syndrome during low-dose venlafaxine treatment in a patient with reduced CYP2D6 activity.
A man in his late 70s with transthyretin amyloidosis experienced recurrent serotonin syndrome while on low-dose venlafaxine treatment.
Genital lichen sclerosus with complete introital obliteration presenting with chronic urinary retention.
A postmenopausal woman with hypothyroidism presented with chronic urinary retention caused by complete introital obliteration due to lichen sclerosus.
Combined mastectomy and beating heart coronary artery bypass grafting: a single-session surgical approach.
A woman in her 70s with papillary ductal carcinoma in situ underwent a combined surgical approach due to severe coronary artery disease.
Deep learning for cardiac CT segmentation for congenital heart disease: A systematic review.
This systematic review evaluates deep learning (DL) approaches for cardiac CT segmentation in congenital heart disease (CHD), analyzing 14 studies.
Exploring the relationship between HIV Testing frequency and sexual behavior, prevention prophylaxis use among MSM in Southern China.
This randomized controlled trial investigated the relationship between HIV testing frequency, sexual behaviors, and prophylaxis use among 327 men who have sex with men (MSM) in Guangxi, China.
Efficacy and safety of T-DXd versus Other HER2-targeted therapies in second-line and later settings for HER2-positive metastatic breast cancer: A Bayesian network meta-analysis.
This Bayesian network meta-analysis evaluated the efficacy and safety of T-DXd compared to other HER2-targeted therapies in 3,339 patients with HER2-positive metastatic breast cancer after trastuzumab-based therapy.
Iatrogenic Large Bowel Perforation Following Image-Guided Pericardiocentesis: A Case Report.
A 72-year-old man with multiple comorbidities underwent fluoroscopy-guided pericardiocentesis for a large pericardial effusion.
Severe neurodevelopmental phenotype with multisystem involvement in VPS16-related mucopolysaccharidosis-like syndrome.
A patient with biallelic VPS16 variants presented with profound developmental delay, early-onset epilepsy, and spasticity, alongside multisystem issues such as recurrent infections and neutropenia.
Scleromyxedema-Associated Myopathy and Vacuolar Myopathy with Monoclonal Gammopathy and Stiffness (VAMMGAS) as manifestations of Monoclonal Gammopathy of Clinical Significance (MGCS): a disease spectrum between autophagy dysfunction and inflammation.
This report discusses two patients with Scleromyxedema-Associated Myopathy (SAM) and one with Vacuolar Myopathy with Monoclonal Gammopathy and Stiffness (VAMMGAS), both associated with Monoclonal Gammopathy of Clinical…
Oral glucose solution for the treatment of persistent asymptomatic neonatal hypoglycemia: a randomized, double-blind, placebo-controlled trial.
This multicenter, randomized, double-blind, placebo-controlled trial evaluated the efficacy of buccal 50% dextrose solution (D50W) in treating persistent asymptomatic hypoglycemia in at-risk late preterm and term…
The effects of dual-task training with different task priorities on physical performance and cognitive status in patients with Parkinson's disease: a single-blind, randomized controlled trial.
This randomized controlled trial investigated the effects of variable-priority dual-task training (V-DTT) and fixed-priority dual-task training (F-DTT) on physical performance and cognitive status in 30 patients with…
Subcutaneous infliximab for maintenance therapy in children and adolescents with inflammatory bowel disease: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the effectiveness and safety of subcutaneous infliximab for maintenance therapy in children and adolescents with inflammatory bowel disease.
Stroke mimic caused by severe hypomagnesemia: a case report and literature review.
A patient with a history of transient neurological deficits presented with stroke-like symptoms, including hemiparesis and aphasia. The patient was on Proton Pump Inhibitors and Metformin.
Time toxicity in cancer care: a systematic review of definitions and measurement methods.
This systematic review examined the definitions and measurement methods of time toxicity in cancer care, involving 56 studies primarily from high-income countries.
The utilisation of international consensus definitions of the disease polytrauma: a systematic review.
This systematic review evaluated the uptake of the Newcastle and Berlin consensus definitions of polytrauma in studies published from 2015 to 2025.
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