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1502 articles

October 202624

Clinical ResearchPreventive Medicine / Public HealthOpen access

Evaluating a multi-vaccine respiratory immunization strategy involving SARS-CoV-2, pneumococcal, and influenza vaccines in adults: A randomized, open-label, multicenter, controlled, non-inferiority Phase IV trial in China.

This randomized, open-label, multicenter Phase IV trial in China assessed immunogenicity and safety when adults aged ≥18 years received an inactivated SARS-CoV-2 vaccine with PPV23 and IIV4, compared with separate…

Hum Vaccin ImmunotherOct 21, 2026Read summary
Clinical ResearchGeriatricsOpen access

Feasibility of a multidimensional interdisciplinary rehabilitation program for people with dementia and their informal primary caregivers - a randomized pilot trial with a caregiver focus.

This randomized pilot trial assessed the feasibility of a person-centred, interdisciplinary rehabilitation program for community-dwelling people with dementia that also provided education and support to informal…

BMC GeriatrOct 21, 2026Read summary
Clinical ResearchNeurologyOpen access

Real-world safety and efficacy of lecanemab in the treatment of Alzheimer's disease: a systematic review and meta-analysis.

This systematic review and meta-analysis pooled real-world studies of lecanemab treatment in people with Alzheimer’s disease, including 37 studies.

J NeurolOct 21, 2026Read summary
Clinical ResearchRheumatologyOpen access

Association between rheumatic diseases and glaucoma risk: a systematic review and meta-analysis of 5.7 million individuals.

This systematic review and meta-analysis examined glaucoma occurrence and risk among people with rheumatic diseases (RD), drawing on 18 studies with 5,766,143 participants.

Int OphthalmolOct 21, 2026Read summary
Case ReportDermatologyOpen access

Blood, ink, and flies: A case report on the house fly (Musca domestica) feeding on active tattooing wounds.

During a tattoo session, a healthy 32-year-old man in Germany experienced repeated landing and feeding attempts by house flies on freshly wounded skin of his right lower leg.

Parasitol ResOct 21, 2026Read case
Clinical ResearchInfectious DiseasesOpen access

Sevuparin in children with severe malaria: a phase I safety and dose-finding trial.

This phase I dose-finding trial assessed sevuparin safety and tolerability in Kenyan and Zambian children with severe malaria.

Nat CommunOct 21, 2026Read summary
Clinical ResearchGastroenterology

Acetic acid chromoendoscopy for detection of neoplastic Barrett's oesophagus: stepped wedge cluster randomised controlled trial (ACID-trial).

This prospective, open-label, stepped-wedge cluster randomised trial assessed whether acetic acid chromoendoscopy (AAC) improved detection of dysplasia or oesophageal adenocarcinoma during Barrett’s oesophagus…

BMJOct 21, 2026Read summary
Clinical ResearchOncology (Medical)

The prognostic value of physical functioning on survival in patients with nonsmall cell lung cancer: a systematic review and meta-analysis.

This systematic review and meta-analysis examined whether objectively measured physical functioning predicts survival in adults with nonsmall cell lung cancer (NSCLC), across surgical and nonsurgical treatment groups.

Eur Respir RevOct 21, 2026Read summary
Clinical ResearchPulmonology

Interventions to increase participation in lung cancer screening programmes: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed interventions to improve informed choice and participation in low-dose CT lung cancer screening.

Eur Respir RevOct 21, 2026Read summary
Case ReportGeneral Surgery

Duplicated Appendix With Mucocele Mimicking an Appendiceal Neoplasm in a 45-Year-Old Woman: A Case Report.

A 45-year-old woman with right lower-quadrant pain and fever had CT evidence of ruptured appendicitis with a loculated peri-appendiceal abscess, which improved after percutaneous drainage and intravenous antibiotics.

Am J Case RepOct 21, 2026Read case
Clinical ResearchGeneral SurgeryOpen access

Systematic review and meta-analysis of mesh versus suture repairs of small umbilical hernias (≤ 2 cm).

This systematic review and meta-analysis compared mesh with suture repair for small umbilical hernias (defects ≤ 2 cm). The primary outcome was postoperative recurrence; secondary outcomes included complications and…

HerniaOct 21, 2026Read summary
Case ReportMedical GeneticsOpen access

Clinically isolated hearing loss as a mild phenotype of PEX26-associated peroxisomal biogenesis disorder: A case report, literature review, and in silico analysis.

An Iranian man presented with bilateral sensorineural hearing loss (SNHL) and no other clinical manifestations at evaluation.

Mol Biol RepOct 21, 2026Read case
Case ReportDermatologyOpen access

Inherited epidermal differentiation disorders (EDD) in pediatric patients from a single Italian referral Center.

A retrospective review at an Italian referral center described three children with congenital, clinically heterogeneous inherited epidermal differentiation disorders.

Eur J PediatrOct 21, 2026Read case
Clinical ResearchOncology (Medical)Open access

Feasibility and safety of an exercise-based prehabilitation intervention before cancer surgery: a pilot randomised controlled trial.

This single-centre pilot randomised controlled trial assessed the feasibility and safety of supervised aerobic prehabilitation before surgery in patients with breast, colorectal, or prostate cancer.

Support Care CancerOct 21, 2026Read summary
Clinical ResearchPediatricsOpen access

Parent-child discrepancies in health-related quality of life in pediatric celiac disease: a systematic review and meta-analysis.

This systematic review and meta-analysis examined child–parent differences in health-related quality of life (HRQoL) among children and adolescents with celiac disease, using the disease-specific CDDUX questionnaire.

Eur J PediatrOct 21, 2026Read summary
Case ReportOphthalmologyOpen access

Use of the 590-nm CAPSULaser in true open-sky penetrating keratoplasty triple procedures: a technical report of two cases.

Two eyes with advanced corneal opacity and visually significant cataract underwent combined penetrating keratoplasty, cataract extraction, and intraocular lens implantation.

Int OphthalmolOct 21, 2026Read case
Clinical ResearchObstetrics & GynecologyOpen access

The effects of perinatal depression and anxiety on memory, attention, and cognitive flexibility: a systematic review and meta-analysis.

This systematic review and meta-analysis examined whether perinatal depressive and anxiety symptoms are associated with memory, attention, and cognitive flexibility.

Arch Womens Ment HealthOct 21, 2026Read summary
Case ReportNeurosurgeryOpen access

Addressing unilateral lambdoid craniosynostosis using endoscopic suturectomy and barrel-stave osteotomies: surgical technique and literature review.

A healthy 2-month-old boy presented with features of left unilateral lambdoid craniosynostosis, including occipitoparietal flattening, ipsilateral mastoid bulge, contralateral parietal bulge, and ear-level asymmetry; 3D…

Childs Nerv SystOct 21, 2026Read case
Clinical ResearchCardiologyOpen access

Effectiveness of cardiac resynchronization therapy in cancer therapy-related cardiac dysfunction: a systematic review and meta-analysis.

This systematic review and random-effects meta-analysis assessed cardiac resynchronization therapy (CRT) outcomes in patients with cancer therapy-related cardiac dysfunction (CTRCD).

Support Care CancerOct 21, 2026Read summary
Clinical ResearchHematology

The role of allogeneic hematopoietic stem cell transplantation in adults with mature T-cell lymphomas.

This Cochrane systematic review and meta-analysis assessed allogeneic stem cell transplantation (alloSCT) for adults with mature T-cell lymphomas (MTCL), as first-line or salvage treatment.

Cochrane Database Syst RevOct 21, 2026Read summary
Clinical ResearchPediatrics

Ruxolitinib for the treatment of pediatric acute and chronic steroid-refractory graft-versus-host disease: Efficacy, safety, and outcomes.

This single-center retrospective study assessed ruxolitinib in children under 18 years with steroid-refractory graft-versus-host disease after allogeneic hematopoietic stem cell transplantation.

Hematol Oncol Stem Cell TherOct 21, 2026Read summary
Clinical ResearchPsychiatry

Semaglutide modulates explore/exploit decision-making in major depressive disorder: A randomized clinical trial.

This secondary analysis of a randomized clinical trial examined whether semaglutide affected explore/exploit decision-making in 72 participants with major depressive disorder (MDD).

Psychol MedOct 21, 2026Read summary
Case ReportNeurosurgery

Ultra high-density, 4096-channel intraoperative neurophysiological brain mapping for functional localization of the human central sulcus.

During resection of a right parafalcine meningioma in a 56-year-old man, four flexible 1024-electrode micro-ECoG arrays were used to record somatosensory evoked potentials from the peri-Rolandic cortex during…

J Neural EngOct 21, 2026Read case
Case ReportPathology (Anatomic & Clinical)Open access

Co-occurrence of aortic dissection and polycystic kidney disease: a case report.

A 19-year-old Caucasian man with no known medical history collapsed during sexual intercourse and died. Post-mortem examination found hemopericardium and aortic dissection in association with polycystic kidney disease…

J Med Case RepOct 21, 2026Read case

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