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1696 articles

September 202624

Clinical ResearchNeurosurgeryOpen access

Pain outcomes and safety in trigeminal neuralgia: a systematic review and meta-analysis comparing percutaneous balloon compression with microvascular decompression.

This systematic review and meta-analysis evaluated the efficacy and safety of percutaneous balloon compression (PBC) versus microvascular decompression (MVD) in treating trigeminal neuralgia (TN) among 1284 patients.

Neurosurg RevSep 28, 2026Read summary
Clinical ResearchPreventive Medicine / Public Health

Prevalence and risk factors for road traffic accidents and mortalities in the Amhara region, Ethiopia: a systematic review and meta-analysis.

This systematic review and meta-analysis examined the prevalence and risk factors of road traffic accidents in the Amhara region of Ethiopia, analyzing data from 12 studies involving 5,222 participants.

Inj PrevSep 28, 2026Read summary
Clinical ResearchGeriatrics

Healthcare spending and factors associated with fall injury in Australia residential aged care: a cohort analysis.

This cohort analysis examined healthcare spending and factors associated with fall injuries in Australian residential aged care, utilizing data from the Opti-Med trial involving 303 participants aged ≥65 years.

Inj PrevSep 28, 2026Read summary
Clinical ResearchUrology

Efficacy and safety of α1-adrenergic receptor antagonists in managing acute urinary retention secondary to benign prostatic hyperplasia: a systematic review and meta-analysis of randomized controlled trials.

This systematic review and meta-analysis evaluated the efficacy of α1-adrenergic receptor antagonists in managing acute urinary retention (AUR) due to benign prostatic hyperplasia (BPH).

Arch Ital Urol AndrolSep 28, 2026Read summary
Case ReportNephrology

Phytate and L-methionine for preventing recurrence of infection renal stones.

This report details a series of cases where patients with recurrent infection renal stones and brushite stones were treated with a combination of phytate and L-methionine.

Arch Ital Urol AndrolSep 28, 2026Read case
Clinical ResearchUrology

Escherichia coli Nissle 1917 for the prevention of recurrent uncomplicated urinary tract infections in women: a pilot randomized placebo-controlled trial.

This pilot multicenter randomized controlled trial evaluated the efficacy of Escherichia coli Nissle 1917 (EcN) in preventing recurrent uncomplicated urinary tract infections (rUTIs) in 50 women.

Arch Ital Urol AndrolSep 28, 2026Read summary
Clinical ResearchNeurology

Evaluating the Clinical Utility of TSPO-PET in MS and the Influence of Methodological Heterogeneity: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated TSPO-PET imaging in multiple sclerosis (MS) patients compared to healthy controls.

Neurol Neuroimmunol NeuroinflammSep 28, 2026Read summary
Case ReportNeurosurgery

Ventral Cervical Spinal Schwannoma Presenting as Progressive Myelopathy.

A male in his 20s presented with a two-year history of progressive paraparesis and urinary incontinence. Neurological examination revealed signs of spasticity and reduced lower-limb power.

Ir Med JSep 28, 2026Read case
Case ReportCardiology

Delayed cardiac conduction disease in a young adult following childhood Chagas infection.

A Bolivian man in his 30s presented to the emergency department with non-exertional chest pain and intermittent second-degree atrioventricular block.

Ir Med JSep 28, 2026Read case
Case ReportMedical Genetics

Type A Insulin Resistance Syndrome Due to a Pathogenic Variant in the INSR Gene.

A woman in her 40s, initially diagnosed with type 1 diabetes, presented with a 30-year history of fluctuating insulin sensitivity and later developed insulin resistance, despite being non-obese.

Ir Med JSep 28, 2026Read case
Case ReportOphthalmology

Non-Arteritic Anterior Ischaemic Optic Neuropathy Associated with Semaglutide use.

A woman in her 70s with vascular risk factors presented with a three-day history of progressive left-sided visual disturbance. Examination revealed a left relative afferent pupillary defect and inferior quadrantopia.

Ir Med JSep 28, 2026Read case
Clinical ResearchOncology (Medical)Open access

Sacituzumab tirumotecan in previously treated metastatic triple-negative breast cancer: a detailed safety analysis of the randomized OptiTROP-Breast01 study.

This randomized controlled trial analyzed the safety profile of sacituzumab tirumotecan (sac-TMT) in 262 patients with previously treated metastatic triple-negative breast cancer.

Breast Cancer ResSep 28, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Population Pharmacokinetics and Exposure-response Analysis of Durvalumab in Patients with Limited-stage Small-cell Lung Cancer in the Phase 3 ADRIATIC Study.

The ADRIATIC study evaluated the population pharmacokinetics and exposure-response relationships of durvalumab in patients with limited-stage small-cell lung cancer (LS-SCLC).

AAPS JSep 28, 2026Read summary
Clinical ResearchOncology (Medical)Open access

A comparison of the efficacy of cognitive-behavioral stress management and acceptance and commitment therapy on the quality of life and fatigue of caregivers of patients with cancer: a randomized controlled trial.

This randomized controlled trial compared the efficacy of cognitive behavioral stress management (CBSM) and acceptance and commitment therapy (ACT) on the quality of life and fatigue in 66 caregivers of cancer patients.

Support Care CancerSep 28, 2026Read summary
Clinical ResearchUrologyOpen access

Intraoperative positioning strategies to improve stone-free outcomes during retrograde intrarenal surgery: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the impact of intraoperative positioning strategies on stone-free outcomes during retrograde intrarenal surgery (RIRS) for renal calculi, involving 998 patients across…

World J UrolSep 28, 2026Read summary
Clinical ResearchHematology

Autologous Hematopoietic Transplantation Reduces Brain Inflammatory and Axoglial Damage Biomarkers in Multiple Sclerosis.

This Phase II multicenter clinical trial investigated the effects of autologous hematopoietic stem cell transplantation (AHSCT) on inflammatory and axoglial damage biomarkers in 24 patients with severe multiple…

Neurol Neuroimmunol NeuroinflammSep 28, 2026Read summary
Clinical ResearchGastroenterology

REFRACTORY BENIGN ESOPHAGEAL STRICTURES: A SYSTEMATIC REVIEW OF ENDOSCOPIC THERAPY.

This systematic review evaluated endoscopic therapies for refractory benign esophageal strictures (RBES) across 18 studies involving 473 patients.

Arq GastroenterolSep 28, 2026Read summary
Clinical ResearchNephrology

A secondary analysis of the SODa-BIC randomized clinical trial using multiple hierarchical composite outcomes.

This post-hoc analysis of the SODa-BIC randomized trial evaluated the effects of sodium bicarbonate on Major Adverse Kidney Events at 30 days in critically ill patients with metabolic acidosis.

Crit Care SciSep 28, 2026Read summary
Case ReportNeurologyOpen access

Acrodynia and CASPR2 Autoimmunity in Elemental Mercury Toxicity.

A 2-year-old girl presented with cough, congestion, and later developed sweating, fussiness, and a pruritic rash after exposure to elemental mercury from a household spill.

J Med ToxicolSep 28, 2026Read case
Case ReportAnesthesiologyOpen access

Effects of Ciprofol- versus Remimazolam-Based Total Intravenous Anesthesia on Postoperative Nausea and Vomiting After Laparoscopic Cholecystectomy: A Randomized Controlled Trial.

Postoperative nausea and vomiting (PONV) remains common after laparoscopic cholecystectomy. Whether ciprofol-based anesthesia reduces PONV compared with remimazolam-based anesthesia remains unclear.

Drug Des Devel TherSep 28, 2026Read case
Case ReportInfectious DiseasesOpen access

Diagnostic Challenges in mNGS for Pulmonary Mucormycosis Presenting with Imaging Features Resembling Those of Lung Cancer.

A 67-year-old woman with diabetes presented with cough and sputum production. Imaging suggested lung cancer due to a right hilar mass, bronchial obstruction, and mediastinal lymphadenopathy.

Int Med Case Rep JSep 28, 2026Read case
Clinical ResearchNeurologyOpen access

Endovascular Treatment for Patients Aged ≥80 Years with Large Ischemic Stroke.

This randomized controlled trial evaluated the effectiveness and safety of endovascular treatment (EVT) in patients aged ≥80 years with large ischemic stroke.

Clin Interv AgingSep 28, 2026Read summary
Clinical ResearchPhysical Medicine & Rehabilitation

Shear wave elastography for assessing lower extremity muscle stiffness after anterior cruciate ligament reconstruction: A systematic review.

This systematic review synthesized studies using shear wave elastography (SWE) to assess lower-extremity muscle stiffness after anterior cruciate ligament reconstruction (ACLR), comparing reconstructed limbs with…

Clin Biomech (Bristol)Sep 28, 2026Read summary
Clinical ResearchCardiologyOpen access

Effects of natriuresis-guided diuretic therapy in men and women with acute heart failure: insights from PUSH-AHF.

This exploratory sex-specific analysis of the multicentre randomised PUSH-AHF trial examined natriuresis-guided diuretic therapy versus standard care in 310 patients with acute heart failure, 45% of whom were women.

Clin Res CardiolSep 28, 2026Read summary

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