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1494 articles

October 202624

Clinical ResearchEndocrinology

Berberine improves diabetic foot ulcer healing after tibial transverse osteotomy by inhibiting the PDGF-B/PDGFRβ signaling pathway .

This prospective, single-centre, randomized, placebo-controlled trial evaluated local berberine injections added to tibial transverse osteotomy (TTO) in patients with Wagner grade 2–4 diabetic foot ulcers.

Pak J Pharm SciOct 26, 2026Read summary
Clinical ResearchOrthopedic Surgery

Efficacy and safety study of diclofenac epolamine topical patch in accelerating rehabilitation of moderate hamstring strain: A randomized controlled trial .

This single-centre, double-blind, placebo-controlled randomised trial evaluated topical diclofenac epolamine alongside rehabilitation in 120 patients with moderate hamstring strain.

Pak J Pharm SciOct 26, 2026Read summary
Clinical ResearchPhysical Medicine & RehabilitationOpen access

A Short Evidence-Based, Belief-Focused Educational Video Improves Back Pain Beliefs but Not Lifting Behaviour in Healthy Office Workers: An Exploratory Randomised Controlled Trial.

This assessor-blind exploratory randomised controlled trial assigned 50 healthy office workers to a brief video about back pain beliefs and management or an anatomy-video control.

Musculoskeletal CareOct 26, 2026Read summary
Clinical ResearchNeurology

From Bench to Bedside: Evaluating the Accuracy of Clinical Sensory Testing in Detecting Somatosensory Disorders. A Systematic Review.

This systematic review assessed the diagnostic accuracy of clinical sensory tests (CSTs) for somatosensory disorders across populations and conditions, comparing test results with reference standards.

Musculoskeletal CareOct 26, 2026Read summary
Clinical ResearchPulmonology

Local Delivery of Interferon-β1a for Respiratory Viral Infections: A Systematic Review.

This PRISMA-guided systematic review assessed locally delivered intranasal or inhaled interferon-β1a for respiratory viral infections, covering clinical trials and experimental evidence.

Rev Med VirolOct 26, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Consequences of opioid exposure in disease-free cancer survivors: A systematic literature review.

This systematic literature review examined the consequences of persistent opioid exposure after curative-intent treatment in disease-free cancer survivors.

J Manag Care Spec PharmOct 26, 2026Read summary
Clinical ResearchPediatrics

Effectiveness of Exercise Snacks in Mitigating Adolescent Problematic Smartphone Use: A Four-Wave Cluster Randomized Controlled Trial.

This four-wave cluster randomized controlled trial tested whether brief, vigorous activity breaks could reduce problematic smartphone use among 386 adolescents in 12 secondary-school classes.

Scand J Med Sci SportsOct 26, 2026Read summary
Clinical ResearchDermatology

Fertility Treatment and Risk of Melanoma: A Certainty-Rated Systematic Review and Meta-Analysis of 3,733,499 Women.

This certainty-rated systematic review and random-effects meta-analysis examined observational evidence on fertility treatment and incident melanoma in women.

Eur J Clin InvestOct 26, 2026Read summary
Clinical ResearchPulmonologyOpen access

Dyspnea Reduction With L-Menthol Inhalation Improves High-Intensity Endurance Running Performance in Healthy Trained Adults.

This randomized, counterbalanced crossover trial tested whether L-menthol inhalation reduces breathlessness and improves high-intensity running performance in 18 trained endurance runners with normal spirometry.

Eur J Sport SciOct 26, 2026Read summary
Clinical ResearchPsychiatryOpen access

An Individual Meta-Analysis of Psychological Treatments for Mood and Personality Disorders Using the Severity Diagnostic System of ICD-11.

This individual patient meta-analysis examined whether ICD-11 personality-disorder severity was associated with short-term outcomes in 1,384 patients from four randomised trials of psychological treatments, mainly…

Personal Ment HealthOct 26, 2026Read summary
Clinical ResearchCardiology

Safety of low lipoprotein(a) levels: the FOURIER trial.

This analysis of the randomized, multicentre FOURIER trial examined associations between lipoprotein(a) [Lp(a)] levels and safety outcomes in patients with stable atherosclerotic cardiovascular disease receiving…

Eur Heart JOct 26, 2026Read summary
Clinical ResearchCardiology

Interleukin-6 and C-reactive protein prognostic value following acute coronary syndrome.

This post hoc prognostic analysis of the multicentre ODYSSEY OUTCOMES randomised trial examined hsCRP and IL-6 in 11,817 patients with recent acute coronary syndrome.

Eur Heart JOct 26, 2026Read summary
Clinical ResearchPhysical Medicine & Rehabilitation

Measurement Properties of Hand-Held Dynamometry for Ankle Strength Assessment: A COSMIN-Based Systematic Review and Meta-Analysis.

This COSMIN-based systematic review and meta-analysis assessed handheld dynamometry (HHD) for measuring isometric ankle muscle strength in healthy individuals.

Musculoskeletal CareOct 25, 2026Read summary
Case ReportPediatrics

Poland Syndrome with transverse upper limb deficiency: beyond the vascular disruption hypothesis.

A neonate presented with right-sided pectoral deficiency and an ipsilateral transverse upper limb deficiency at the carpal level.

J Hand Surg Eur VolOct 25, 2026Read case
Case ReportGastroenterology

Extensive Arterial Thrombosis Complicating Acute Pancreatitis: A Case Report and Literature Review.

A 61-year-old man with chronic pancreatitis developed acute interstitial edematous pancreatitis. Four weeks after presentation, persistent dyspepsia prompted contrast-enhanced CT, which showed pancreatic pseudocysts and…

Korean J GastroenterolOct 25, 2026Read case
Case ReportGeneral Surgery

Fishbone-Induced Gastrointestinal Perforation: A 21-Case Series from Vietnam.

This retrospective series included 21 patients treated for fishbone-induced gastrointestinal perforation at a tertiary hospital in southern Vietnam.

Korean J GastroenterolOct 25, 2026Read case
Clinical ResearchOncology (Medical)Open access

Prognostic associations between patient-reported outcomes and progression-free and overall survival in advanced gastric or gastroesophageal junction adenocarcinoma with PD-L1 TAP score ≥ 5%: results from the RATIONALE-305 trial.

This analysis of the randomised RATIONALE-305 trial examined whether longitudinal patient-reported outcomes (PROs) were associated with progression-free survival (PFS) and overall survival (OS) in patients with advanced…

Qual Life ResOct 25, 2026Read summary
Case ReportMedical GeneticsOpen access

A novel PGAP1 splice-site variant expanding the clinical and molecular spectrum of GPI-anchor disorders.

A patient with neurodevelopmental impairment was found to carry a novel homozygous PGAP1 splice-site variant, NM_024989.4.1173 + 1G > A.

Mol Biol RepOct 25, 2026Read case
Clinical ResearchCardiologyOpen access

A randomized study comparing plant sterol- and soluble fiber-enriched soymilk with plain soymilk in adults with elevated LDL cholesterol.

This randomized controlled trial compared plant sterol- and soluble fiber-enriched soymilk with plain soymilk in 242 adults with hypercholesterolemia, untreated or on stable lipid-lowering therapy.

Eur J NutrOct 25, 2026Read summary
Clinical ResearchHematologyOpen access

Reduced-dose alternate-day oral iron supplementation in women with iron deficiency: a randomized controlled trial.

This 42-day, randomized, parallel-group active-controlled trial compared two oral iron regimens in 66 women aged 18–50 years with iron deficiency (serum ferritin < 30 ng/mL).

Eur J NutrOct 25, 2026Read summary
Case ReportCardiothoracic Surgery

Tricuspid Chordae Tendineae Rupture Detected After Repair of a Delayed Traumatic Left Ventricular Aneurysm: A Case Report.

After a fall from a height, a patient presented 54 days later with rupture of a posterior left ventricular aneurysm. Venoarterial extracorporeal membrane oxygenation provided circulatory support before surgical aneurysm…

Am J Case RepOct 25, 2026Read case
Case ReportInfectious Diseases

Disseminated Trimethoprim/Sulfamethoxazole-Resistant Nocardiosis in Renal Transplant Recipient, India.

A renal transplant recipient in India taking trimethoprim/sulfamethoxazole prophylaxis presented with fever, hemoptysis, and neurologic deficits.

Emerg Infect DisOct 24, 2026Read case
Case ReportInfectious Diseases

Systemic Spiroplasma turonicum Infection Manifested as Knee Arthritis, France, 2025.

An immunocompromised patient in southeast France presented with fever, knee arthritis, and skin erythema. Blood and joint samples tested positive for Spiroplasma turonicum, an intracellular gram-negative bacterium…

Emerg Infect DisOct 24, 2026Read case
Case ReportInfectious Diseases

Fatal Rickettsia parkeri Rickettsiosis in Immunocompromised Pediatric Patient, Georgia, USA, 2025.

A 3-year-old boy in Georgia, USA, receiving chemotherapy for B-cell acute lymphoblastic leukemia was hospitalized with febrile neutropenia.

Emerg Infect DisOct 24, 2026Read case

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