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1487 articles

October 202624

Case ReportPediatricsOpen access

Varicella zoster vasculopathy presenting as bilateral subdural haematoma in an infant: case report of a rare case and literature review.

A 6-month-old boy developed chickenpox with fever, irritability, and a vesicular rash. Although the rash and fever resolved, he had persistent irritability, poor feeding, intermittent vomiting, developmental regression…

Childs Nerv SystOct 24, 2026Read case
Case ReportMedical GeneticsOpen access

Clinical manifestations of Armfield syndrome in females with heterozygous FAM50A variants and skewed X-chromosome inactivation.

A Spanish female patient presented with macrocephaly, global developmental delay, and leukoencephalopathy. Whole-exome sequencing identified a novel de novo heterozygous FAM50A variant, c.905 A > T (p.His302Leu).

Neurol SciOct 24, 2026Read case
Clinical ResearchCardiothoracic SurgeryOpen access

Uniportal versus multiportal robotic-assisted thoracic surgery for anatomical pulmonary resection: a systematic review and meta-analysis of perioperative recovery and surgical quality.

This systematic review and meta-analysis compared uniportal/single-port with multiportal robotic-assisted thoracic surgery for anatomical pulmonary resection.

J Robot SurgOct 24, 2026Read summary
Clinical ResearchPsychiatryOpen access

Efficacy and safety of GLP-1 receptor agonists for antipsychotic-related overweight and metabolic dysregulation: a systematic review and meta-analysis.

This systematic review and meta-analysis pooled randomized controlled trials of GLP-1 receptor agonists in adults receiving antipsychotic treatment for overweight or metabolic dysregulation.

Eur J Clin PharmacolOct 24, 2026Read summary
Case ReportNeurologyOpen access

Disease trajectory in cerebral amyloid angiopathy: a matter of time.

A 75-year-old woman diagnosed with possible cerebral amyloid angiopathy (CAA) in 2016 had a spontaneous right prerolandic convexal subarachnoid hemorrhage and MRI evidence of small-vessel disease.

Neurol SciOct 24, 2026Read case
Clinical ResearchNeurologyOpen access

Mapping the prevalence of Epstein-Barr virus and multiple sclerosis in Middle East and North Africa: a systematic review and meta-analysis.

This systematic review and meta-analysis mapped published estimates of multiple sclerosis (MS) prevalence and Epstein-Barr virus (EBV) seroprevalence in Middle East and North Africa populations.

J NeurovirolOct 24, 2026Read summary
Clinical ResearchDermatologyOpen access

Combination therapy of carbon dioxide laser with topical halometason cream and 308 nm excimer laser for the treatment of vitiligo: an optimized combined treatment protocol.

This randomized controlled trial evaluated fractional CO₂ laser plus topical halometasone cream and 308-nm excimer lamp therapy for refractory non-segmental vitiligo, compared with excimer therapy, a topical calcineurin…

Lasers Med SciOct 24, 2026Read summary
Case ReportHematologyOpen access

HHV8-associated multicentric Castleman disease with Kaposi sarcoma in an immunocompetent patient: a case report and review of the literature.

A 57-year-old man presented with five months of generalized lymphadenopathy, weakness, cough, fever, and weight loss. HIV, CMV, EBV, and tuberculosis tests were negative.

J HematopOct 24, 2026Read case
Case ReportNeurologyOpen access

Copy number variants across the developmental epilepsy-developmental and epileptic encephalopathy spectrum: an Indonesian case series.

A retrospective series from a tertiary hospital in Yogyakarta described four Indonesian children with developmental epilepsy or developmental and epileptic encephalopathy and pathogenic copy number variants.

NeurogeneticsOct 24, 2026Read case
Clinical ResearchGeneral SurgeryOpen access

Timing of diverting ileostomy closure after low anterior resection for rectal cancer: a GRADE-assessed systematic review and meta-analysis of early and delayed closure.

This GRADE-assessed systematic review and meta-analysis compared early with delayed diverting ileostomy closure after low anterior resection for rectal cancer.

Langenbecks Arch SurgOct 24, 2026Read summary
Clinical ResearchHematologyOpen access

Evaluating the effectiveness of the eHealth-faciLitated SMILe-integrated care model on treatment burden, quality of life and graft-versus-host disease after allogeneic stem cell transplantation: results of two European randomized controlled implementation studies.

Two multicentre, hybrid effectiveness-implementation randomised controlled trials at European allogeneic stem cell transplantation (alloSCT) centres evaluated SMILe-ICM, an eHealth-supported, advanced practice nurse-led…

Ann HematolOct 24, 2026Read summary
Case ReportUrology

Perineal Urethrostomy After Urethral Stricture: Step-by-Step Surgical Technique.

A 73-year-old man with complex, recurrent urethral stricture after multiple reconstructive and endoscopic procedures underwent perineal urethrostomy. His history also included Bowen’s disease of the glans penis.

Int Braz J UrolOct 23, 2026Read case
Case ReportUrology

Extending the Graft Harvesting Area in Severe Penoscrotal Hypospadias: The Rainbow Technique.

A 2-year-old with severe penoscrotal hypospadias, a scrotal meatus, bifid scrotum, and chordee exceeding 90° underwent first-stage reconstruction.

Int Braz J UrolOct 23, 2026Read case
Case ReportUrology

Robot-Assisted Radical Prostatectomy in a Post-Enucleation Gland.

A 64-year-old man was found to have right-lobe ISUP grade 3 prostate adenocarcinoma after HoLEP for benign prostatic obstruction. PSA was 0.51 ng/mL, and MRI showed a 0.4 cm PI-RADS 4 lesion.

Int Braz J UrolOct 23, 2026Read case
Case ReportUrology

Robotic Totally Intracorporeal Bilateral Boari Flap Reconstruction for Complex Bilateral Ureteral Strictures: A Step-by-Step Technique.

A 42-year-old woman with complex bilateral mid- and distal ureteral strictures underwent robotic, totally intracorporeal bilateral Boari flap reconstruction.

Int Braz J UrolOct 23, 2026Read case
Case ReportNeurology

Intermittent Maple Syrup Urine Disease Presenting With Chronic Demyelinating Polyneuropathy: A Genetically Confirmed DBT-Related Case.

A female patient with intermittent maple syrup urine disease (MSUD), genetically confirmed by compound heterozygous pathogenic DBT variants, had recurrent ataxic episodes from early childhood.

J Peripher Nerv SystOct 23, 2026Read case
Clinical ResearchGastroenterology

Impact of YAQ001 on the Gut Microbiome, Permeability and Markers of Systemic Inflammation in Patients With Cirrhosis.

This double-blind randomised controlled substudy examined YAQ001’s effects on the gut microbiome and exploratory markers of gut permeability and systemic inflammation in 28 patients with cirrhosis.

Liver IntOct 23, 2026Read summary
Clinical ResearchInfectious Diseases

Evaluation of the Achievement of a Pharmacodynamic Target of Piperacillin-Tazobactam for the Population With Obesity: An Open Randomized Controlled Feasibility Study (TAZO-OBESITY Trial).

The open-label randomized feasibility trial TAZO-OBESITY compared standard with prolonged piperacillin-tazobactam infusions in patients with obesity (BMI ≥30 kg/m²).

Fundam Clin PharmacolOct 23, 2026Read summary
Clinical ResearchGastroenterology

Gut virome remodeling after fecal microbiota transplantation is associated with virus-bacteria co-variation and metabolic response in obesity and type 2 diabetes.

This randomized controlled trial examined longitudinal fecal virome and bacteriome changes after fecal microbiota transplantation (FMT) in people with obesity and type 2 diabetes.

Gut MicrobesOct 23, 2026Read summary
Clinical ResearchRadiology (Diagnostic)

The entorhinal cortex atrophy score for diagnostic distinction between phases of the Alzheimer's disease continuum.

This systematic review assessed the Entorhinal Cortex Atrophy (ERICA) visual score for distinguishing subjective cognitive decline (SCD), mild cognitive impairment (MCI), and Alzheimer’s disease (AD) dementia.

Arq NeuropsiquiatrOct 23, 2026Read summary
Clinical ResearchGeriatrics

Feasibility of a Co-Designed Personalized Cognitive Reablement Program Delivered via Digital Voice Assistants for Older Adults Living With Early-Stage Dementia or Mild Cognitive Impairment: Pilot Randomized Controlled Trial.

This nonblinded pilot randomized controlled trial assessed the feasibility and potential effectiveness of VOICE-COG, a personalized cognitive reablement program delivered through digital voice assistants, in adults aged…

JMIR AgingOct 23, 2026Read summary
Clinical ResearchObstetrics & Gynecology

The Impact of Telemedicine Interventions on Maternal and Fetal Outcomes in Women With Gestational Diabetes: Systematic Review and Meta-Analysis of Randomized Controlled Trials.

This systematic review and meta-analysis pooled 23 randomized controlled trials involving 3055 women with gestational diabetes to assess telemedicine and maternal and fetal outcomes.

J Med Internet ResOct 23, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Precancerous cervical lesions and associated factors among HIV-positive women in Southern and Eastern African countries: A systematic review and meta-analysis.

This systematic review and meta-analysis pooled evidence on precancerous cervical lesions (PCCL) and associated factors among women living with HIV in Southern and Eastern Africa.

PLoS OneOct 23, 2026Read summary
Clinical ResearchEndocrinology

Search for the glycated hemoglobin target minimizing mortality among people with type 2 diabetes with rare incidence of treatment-related severe hypoglycemia - Epidemiologic analysis of J-DOIT3 randomized controlled trial.

This landmark analysis of the J-DOIT3 randomized controlled trial examined associations between updated HbA1c and cardiovascular outcomes or mortality among people with type 2 diabetes, in a setting where severe…

PLoS OneOct 23, 2026Read summary

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