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1778 articles

October 202624

Clinical ResearchHematology

Rapid manufactured CAR-T cells enriched for CD45RA-negative T cells exhibit superior persistence compared to conventional CAR-T therapy.

This comparative study evaluated InstanCAR-T, a rapid CD19 CAR-T manufacturing protocol enriched for CD45RA-negative T cells, against conventional CAR-T in laboratory assays, murine B-ALL models, and a Phase I clinical…

Cancer LettOct 2, 2026Read summary
Clinical ResearchOncology (Medical)

Hypofractionated 44 Gy in 20 fractions versus conventional chemoradiation in cervical cancer: 2-year results of the randomized HYPOCx-iRex trial with an exploratory pooled analysis of a single-institute EMBRACE-II cohort.

The randomized HYPOCx-iRex trial compared hypofractionated chemoradiation (44 Gy in 20 fractions) with conventional chemoradiation (45 Gy in 25 fractions) for locally advanced cervical cancer; an exploratory pooled…

BrachytherapyOct 2, 2026Read summary
Case ReportPediatrics

Primary Surgical Resection of Localized Cervical Kaposiform Hemangioendothelioma in a Neonate: A Potentially Curative Strategy in Selected Patients.

A term female neonate had a 4 × 4 cm cervical mass at birth. Imaging showed a well-circumscribed, highly vascular lesion without infiltration or compression of vital structures; no coagulopathy was detected.

J Pediatr Hematol OncolOct 2, 2026Read case
Clinical ResearchPediatrics

Opioid Use and Family Members' Experiences of Opioids in Paediatric Cancer Pain Management: An Integrative Review.

This integrative review analyzed opioid use in pediatric cancer pain management and family members' experiences. Sixteen peer-reviewed articles were reviewed, revealing that morphine and fentanyl are the most commonly…

Scand J Caring SciOct 1, 2026Read summary
Clinical ResearchPsychiatry

Irritability in the Mix: An Exploratory Study of the Role of Irritability in Characterising Mood Disorders.

This randomized controlled trial explored the relationship between irritability and mixed states in 82 patients with bipolar disorder over 18 months.

Bipolar DisordOct 1, 2026Read summary
Clinical ResearchPsychiatry

Bipolar Disorder and Perimenopause: An Update.

This systematic review examined the relationship between bipolar disorder (BD) and perimenopause, analyzing 14 studies from various countries.

Bipolar DisordOct 1, 2026Read summary
Clinical ResearchEndocrinology

Effect of a walnut-based low carbohydrate diet on fat redistribution and visceral fat accumulation in people with central obesity: A randomized controlled trial.

This randomized controlled trial investigated the effects of a walnut-based low carbohydrate diet (w-LCD) on fat redistribution and visceral fat accumulation in individuals with central obesity over 12 weeks.

Asia Pac J Clin NutrOct 1, 2026Read summary
Case ReportNeurology

Acute Motor and Sensory Axonal Neuropathy Variant of Guillain-Barré Syndrome: A Nurse-Led Intensive Care Case Report.

A 40-year-old man presented with acute quadriparesis and respiratory distress after a febrile illness. He was diagnosed with acute motor and sensory axonal neuropathy, complicated by multiple infections including…

Crit Care NurseOct 1, 2026Read case
Clinical ResearchOncology (Medical)

Giredestrant plus Everolimus in Advanced Breast Cancer.

This phase 3 randomized controlled trial evaluated the efficacy of giredestrant plus everolimus versus standard endocrine therapy plus everolimus in patients with ER-positive, HER2-negative advanced breast cancer who…

N Engl J MedOct 1, 2026Read summary
Clinical ResearchNephrology

Mediation Analysis of Urine Osmolality and Response to Tolvaptan in Autosomal Dominant Polycystic Kidney Disease: A Post Hoc Assessment.

This post hoc analysis of the TEMPO 3:4 randomized controlled trial evaluated urine osmolality (Uosm) as a biomarker for long-term response to tolvaptan in patients with autosomal dominant polycystic kidney disease…

Nephrology (Carlton)Oct 1, 2026Read summary
Clinical ResearchOncology (Medical)

Efficacy and Safety of PD-1/PD-L1 Inhibitors Combined With Anti-Angiogenic Tyrosine Kinase Inhibitors for Recurrent or Metastatic Nasopharyngeal Carcinoma: A Systematic Review and Single-Arm Meta-Analysis.

This systematic review and meta-analysis evaluated the efficacy and safety of PD-1/PD-L1 inhibitors combined with anti-angiogenic tyrosine kinase inhibitors in 357 patients with recurrent or metastatic nasopharyngeal…

Cancer MedOct 1, 2026Read summary
Case ReportMedical Genetics

Hereditary Spastic Paraplegia Type 11: A Comprehensive Case Report.

An 18-year-old woman with no significant medical history presented with a 2-year history of progressive weakness and stiffness in both lower limbs, leading to difficulty in walking.

Mymensingh Med JOct 1, 2026Read case
Case ReportNeurosurgery

A Mysterious Case of Giant Scalp Devil's Horn with Intracranial Extension Removed by Surgical Excision.

A 60-year-old male presented with altered consciousness, chronic headaches, blurred vision, and scalp swelling. Imaging revealed a giant cutaneous horn in the scalp with underlying bony erosion and intracranial…

Mymensingh Med JOct 1, 2026Read case
Case ReportNeurosurgery

The Urgent Surgical Outcome of Intracranial Subdural Empyema: A Case Presentation.

A patient presented unconscious due to intracranial subdural empyema, a severe brain infection. Urgent surgical intervention was performed, leading to a rapid recovery postoperatively.

Mymensingh Med JOct 1, 2026Read case
Clinical ResearchOncology (Medical)

Intermittent Pneumatic Compression in Patients with Postmastectomy Lymphedema: A Randomized Controlled Trial.

This randomized controlled trial evaluated the effects of intermittent pneumatic compression (IPC) combined with exercises on upper limb lymphedema in 21 patients post-mastectomy.

Mymensingh Med JOct 1, 2026Read summary
Clinical ResearchGeriatrics

Association of Sarcopenia With Global, Motor, Cognitive, and Swallowing Function Prognosis in Stroke Patients: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated the impact of sarcopenia on functional outcomes in stroke patients. Analyzing 36 cohort studies, it found that patients with sarcopenia had a significantly higher risk…

Brain BehavOct 1, 2026Read summary
Case ReportInfectious Diseases

Human Infection with Japanese Encephalitis Virus Genotype V, China, 2025.

A human case of Japanese encephalitis virus genotype V (JEV GV) was confirmed in China through serological testing, sequencing, and quantitative reverse transcription PCR.

Emerg Infect DisOct 1, 2026Read case
Case ReportInfectious Diseases

Chlamydia psittaci Meningitis, Chile, 2023.

A 50-year-old farm worker in Chile presented with meningitis, which was confirmed to be caused by Chlamydia psittaci through cerebrospinal fluid quantitative real-time PCR and serology.

Emerg Infect DisOct 1, 2026Read case
Clinical ResearchEndocrinology

Pharmacokinetic and Pharmacodynamic Drug-Drug Interactions Between Cofrogliptin and Metformin in Healthy Subjects: A Single-Center, Single-Arm, Phase I Study in China.

This single-center, single-arm Phase I study assessed drug-drug interactions between cofrogliptin and metformin in 22 healthy Chinese subjects.

Clin Pharmacol Drug DevOct 1, 2026Read summary
Clinical ResearchOncology (Medical)

A Phase I Study of Nimotuzumab Combined with Irinotecan in Chinese Patients with Advanced Solid Tumors.

This Phase I study assessed the pharmacokinetics and safety of nimotuzumab combined with irinotecan in Chinese patients with advanced solid tumors.

Clin Pharmacol Drug DevOct 1, 2026Read summary
Clinical ResearchInfectious Diseases

Pharmacokinetics, Immunogenicity, and Safety of a Modified YTE Antibody in Healthy Adults.

This Phase I randomized controlled trial evaluated the pharmacokinetics, immunogenicity, and safety of REGN17092, a modified YTE antibody targeting SARS-CoV-2, in 40 healthy adults.

Clin Pharmacol Drug DevOct 1, 2026Read summary
Case ReportInfectious Diseases

Buruli Ulcer Acquired From Ringtail Possum Rescue.

A patient presented with a Buruli ulcer, which was likely acquired from a scratch by a ringtail possum during a rescue attempt. This case highlights a newly recognized transmission route for Buruli ulcer.

Med J AustOct 1, 2026Read case
Clinical ResearchGastroenterology

Enhanced recovery after colorectal surgery in patients with inflammatory bowel disease to reduce hospital length of stay: A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the impact of enhanced recovery after surgery (ERAS) protocols on adult patients with inflammatory bowel disease (IBD).

Colorectal DisOct 1, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Systematic Review and Meta-analysis of Group B Streptococcus Rectovaginal Colonization Rates and Serotype Distribution among Pregnant Women, Asia-Pacific Region, 2014-2025.

This systematic review and meta-analysis examined group B Streptococcus (GBS) rectovaginal colonization rates among 978,150 pregnant women in the Asia-Pacific region.

Emerg Infect DisOct 1, 2026Read summary

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