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1616 articles

October 202624

Clinical ResearchInfectious Diseases

Safety and immunogenicity of a first-generation modified vaccinia virus Ankara-vectored SARS-CoV-2 vaccine candidate with mRNA-based booster vaccination: A phase 1 trial.

This phase 1 trial assessed safety and immune responses to the MVA-vectored SARS-CoV-2 vaccine MVA-SARS-2-S in 30 healthy, SARS-CoV-2-naive adults given two doses 28 days apart, with six-month follow-up.

Hum Vaccin ImmunotherOct 15, 2026Read summary
Clinical ResearchEndocrinology

AI-Driven Lifestyle Interventions for Reducing Diabetes Risk: Systematic Review.

This systematic review assessed AI-driven digital lifestyle interventions for people with prediabetes or elevated diabetes risk, including healthy participants in feasibility studies.

J Med Internet ResOct 15, 2026Read summary
Clinical ResearchFamily Medicine

Improving Musculoskeletal Care Quality With a Web-Based Clinical Decision Support System in UK Primary Care: Mixed Methods Cluster-Randomized Controlled Trial.

This mixed methods, cluster-randomized controlled trial evaluated CrossCover, a web-based clinical decision support system for adult musculoskeletal consultations in UK general practice.

J Med Internet ResOct 15, 2026Read summary
Clinical ResearchVascular Surgery

The Moderating Effects of Race and Ethnicity on a Motivational Interviewing Intervention for Improving Physical Health Among Patients With Peripheral Artery Disease: Secondary Analysis of a Pilot Randomized Trial.

This secondary analysis of a pilot randomized trial examined whether social determinants of health modified motivational interviewing (MI) effects on walking distance and weight among community-dwelling adults with…

JMIR Form ResOct 15, 2026Read summary
Clinical ResearchPreventive Medicine / Public Health

Acceptability and Feasibility of an Islamic Faith-Based Smoking Cessation Intervention Delivered via WhatsApp for Muslim Smokers in Saudi Arabia: Pilot Randomized Controlled Trial.

This two-arm pilot randomized controlled trial assessed the feasibility, acceptability, and preliminary outcomes of a 21-day Islamic faith-based smoking cessation intervention delivered by WhatsApp to adult Muslim…

JMIR Form ResOct 15, 2026Read summary
Clinical ResearchNeurology

The ability of the commercial inertial measurement unit-based gait system in determining Parkinson's disease: A systematic review with meta-analysis of cross-sectional studies.

This systematic review and meta-analysis of cross-sectional studies assessed whether commercial inertial measurement unit (IMU)-based gait systems distinguish people with Parkinson’s disease (PD) from healthy controls.

PLoS OneOct 15, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Impact of structured sexual health training incorporating standardised patients on health professions students' sexual health communication competence: A single-blind randomised controlled trial in Tanzania.

This single-blind, parallel-group randomised controlled trial evaluated structured sexual health training incorporating standardised patients (SPs) among undergraduate medical and nursing students at a university in…

PLoS OneOct 15, 2026Read summary
Clinical ResearchPhysical Medicine & Rehabilitation

AI-Enabled Telerehabilitation for Chronic Nonspecific Neck Pain: Multicenter Randomized Controlled Trial.

This multicenter, prospective, parallel-group randomized noninferiority trial compared AI-enabled home telerehabilitation with exercise-matched outpatient rehabilitation in people with chronic nonspecific neck pain…

JMIR Form ResOct 15, 2026Read summary
Clinical ResearchAnesthesiology

Quality of recovery after arthroscopic meniscectomy with remimazolam or propofol anesthesia: A randomized controlled trial.

This randomized controlled trial compared propofol-based with remimazolam-based total intravenous anesthesia in adults undergoing elective arthroscopic meniscectomy.

PLoS OneOct 15, 2026Read summary
Clinical ResearchPediatrics

Bacterial infections and antibiotic susceptibility in children with sickle-cell anemia on malaria chemoprevention using Dihydroartemisinin-piperaquine (DP) or Sulfadoxine-pyrimethamine (SP) in Uganda.

This analysis nested within a randomized, double-blind trial assessed bacterial infections and antimicrobial resistance among Ugandan children aged 6 months to 15 years with sickle-cell anemia receiving weekly…

PLoS OneOct 15, 2026Read summary
Clinical ResearchCardiology

Coronary microvascular dysfunction in patients undergoing transcatheter aortic valve implantation: A systematic review and meta-analysis.

This systematic review and meta-analysis examined coronary microvascular dysfunction (CMD) in adults with severe aortic stenosis undergoing transcatheter aortic valve implantation (TAVI).

PLoS OneOct 15, 2026Read summary
Case ReportEndocrinology

Behind the Sella: A Rare Case of Pituicytoma Mimicking a Pituitary Adenoma.

A 48-year-old man presented with symptoms of hypogonadism, headaches, and visual field defects. Testing showed hypogonadotropic hypogonadism and hyperprolactinemia, while MRI revealed a sellar-suprasellar mass initially…

Am J Case RepOct 15, 2026Read case
Case ReportVascular Surgery

PERCUTANEOUS MECHANICAL THROMBECTOMY: A NEW TOOL IN THE TREATMENT OF ACUTE MESENTERIC ISCHEMIA.

An 82-year-old woman with atrioventricular block, hypertension, and dementia presented with acute abdominal pain that had begun three days earlier.

Port J Card Thorac Vasc SurgOct 15, 2026Read case
Clinical ResearchOncology (Medical)Open access

A Meta-Analysis on Outcomes of Zanidatamab Plus Chemotherapy in Patients with Advanced HER2-positive Gastroesophageal Adenocarcinoma.

This meta-analysis pooled outcomes from three clinical trials involving 685 patients with advanced HER2-positive gastroesophageal adenocarcinoma treated first-line with zanidatamab plus chemotherapy, with or without…

J Gastrointest CancerOct 15, 2026Read summary
Clinical ResearchUrologyOpen access

Association of immune checkpoint-related polymorphisms in PD-1, PD-L1, and CTLA-4 genes with susceptibility to genitourinary cancer: a meta-analysis.

This meta-analysis pooled evidence from 16 case-control studies examining six single-nucleotide polymorphisms in PD-1, PD-L1, and CTLA-4 genes and susceptibility to genitourinary cancers, including urothelial, renal…

Immunol ResOct 15, 2026Read summary
Clinical ResearchGeneral SurgeryOpen access

Uniportal versus Multiportal Video-Assisted Thoracoscopic Surgery for Minimally Invasive Esophagectomy in Esophageal Cancer: A GRADE-Assessed Systematic Review and Meta-Analysis.

This GRADE-assessed systematic review and meta-analysis compared uniportal (uVATS) with multiportal video-assisted thoracoscopic surgery (mVATS) for minimally invasive esophagectomy in adults with esophageal cancer.

J Gastrointest CancerOct 15, 2026Read summary
Clinical ResearchPreventive Medicine / Public HealthOpen access

Umbrella review of low-level light therapy: evidence across clinical conditions.

This umbrella review synthesized systematic reviews and meta-analyses of low-level light therapy (LLLT) in humans across clinical conditions. It included 100 reviews, covering 790 unique primary studies.

Lasers Med SciOct 15, 2026Read summary
Clinical ResearchOrthopedic SurgeryOpen access

Robotic-assisted conversion of unicompartmental to total knee arthroplasty: a systematic review.

This PRISMA-guided systematic review assessed robotic-assisted conversion of unicompartmental knee arthroplasty (UKA) to total knee arthroplasty (TKA).

J Robot SurgOct 15, 2026Read summary
Clinical ResearchCardiologyOpen access

Immune checkpoint inhibitor-related myocarditis, myositis, and myasthenia gravis overlap syndrome: a single-center case series and systematic review.

The aim of our study was to evaluate the clinical, diagnostic, therapeutic, and prognostic features of immune checkpoint inhibitor-related myocarditis, myositis, and myasthenia gravis overlap syndrome (IM3OS).

Support Care CancerOct 15, 2026Read summary
Clinical ResearchPediatricsOpen access

Comparison of fecal continence and bowel function scoring systems following anorectal malformation repair: a systematic review.

This systematic review assessed whether fecal continence and bowel function scoring systems give comparable results when applied to the same cohorts after anorectal malformation repair.

Pediatr Surg IntOct 15, 2026Read summary
Case ReportGeneral Surgery

3D-printed reduction guide with hinge and window. Design for conservative veneer preparations.

A 36-year-old woman sought improvement of her smile. Existing ceramic veneers from the maxillary right to left canine showed staining and crack lines, with mild gingival recession around the restored teeth.

Int J Esthet DentOct 15, 2026Read case
Case ReportGeneral Surgery

Micro-layering technique for esthetic rehabilitation. A case report.

A male patient sought esthetic rehabilitation for a diastema between the central incisors, mismatched tooth shapes, and overall dental disharmony.

Int J Esthet DentOct 15, 2026Read case
Clinical ResearchPsychiatry

Artificial intelligence EEG biomarkers for schizophrenia diagnosis: Systematic review with PROBAST+AI assessment.

This systematic review assessed the diagnostic performance and methodological quality of AI models using resting-state EEG to identify schizophrenia or first-episode psychosis.

Eur PsychiatryOct 15, 2026Read summary
Clinical ResearchHematology

TRANSFORM-1 phase 3 study: efficacy and safety of navitoclax plus ruxolitinib in patients with untreated myelofibrosis.

TRANSFORM-1 was a multicentre, randomised phase 3 trial comparing navitoclax plus ruxolitinib with placebo plus ruxolitinib in Janus kinase inhibitor-naïve adults with intermediate-2 or high-risk myelofibrosis.

BloodOct 15, 2026Read summary

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