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1704 articles

October 202624

Case ReportPsychiatryOpen access

Managing 7-Hydroxymitragynine Use Disorder with Buprenorphine-Naloxone.

A patient who had used kratom to stop illicit opioids developed tolerance and transitioned to 7-hydroxymitragynine, believing the plant-derived product was safe.

Hawaii J Health Soc WelfOct 7, 2026Read case
Case ReportAnesthesiologyOpen access

Effect of a Single Subanesthetic Dose of Esketamine on Gastrointestinal Recovery After Laparoscopic Colorectal Cancer Surgery: A Randomized, Outcome-Assessor-Blinded, Placebo-Controlled Trial.

Postoperative gastrointestinal dysfunction (POGD) and Postoperative gastrointestinal intolerance (POGI) remain a critical challenge in abdominal surgery, particularly for colorectal cancer patients undergoing…

Drug Des Devel TherOct 7, 2026Read case
Clinical ResearchRheumatology

Prospective controlled study of the recombinant zoster vaccine in autoimmune rheumatic disease: robust seroconversion despite intravenous cyclophosphamide.

This subanalysis of a prospective, randomized, placebo-controlled trial assessed recombinant zoster vaccine (RZV) responses in patients with autoimmune rheumatic disease receiving intravenous cyclophosphamide (IVCYC)…

VaccineOct 7, 2026Read summary
Case ReportNeurologyOpen access

Multiple Sclerosis During Pregnancy and the Postpartum Period: Diagnostic and Multidisciplinary Challenges in Two Cases.

The report describes two pregnant women with progressive focal neurological symptoms and brain MRI abnormalities concerning for central nervous system demyelination.

Int Med Case Rep JOct 7, 2026Read case
Case ReportHematology

Successful treatment of hairy cell leukemia with TP53 abnormality using cladribine combined with low-dose rituximab: a case report and literature review.

An elderly man with classical hairy cell leukemia (HCL) had BRAF V600E positivity, a TP53 deletion detected by fluorescence in situ hybridization, and bone marrow fibrosis.

Anticancer DrugsOct 7, 2026Read case
Case ReportOncology (Medical)

Case report: successful use of repotrectinib in a ROS1 fusion-positive lung adenocarcinoma patient with severe renal insufficiency and prior tyrosine kinase inhibitor treatment failure.

A 69-year-old woman with advanced lung adenocarcinoma harboring an SDC4–ROS1 fusion had bilateral pulmonary lesions, mediastinal lymphadenopathy, and pleural effusions.

Anticancer DrugsOct 7, 2026Read case
Clinical ResearchRadiology (Diagnostic)

Fractal radiomics as a virtual biopsy in glioma: A systematic review and meta-analysis of molecular status, radiogenomic associations, and survival outcomes.

This systematic review and meta-analysis assessed whether fractal-based imaging features can predict molecular alterations and outcomes in glioma.

J Clin NeurosciOct 7, 2026Read summary
Clinical ResearchRadiology (Diagnostic)

Adult diagnostic reference levels in computed tomography: A systematic review and analysis of regional variability.

This systematic review examined adult computed tomography diagnostic reference levels (DRLs) across regions and examination types.

Eur J RadiolOct 7, 2026Read summary
Clinical ResearchUrology

MRI-derived radiomics for prostate cancer active surveillance: a systematic review.

This PRISMA 2020 systematic review assessed MRI-derived radiomic and artificial intelligence models for selecting men with prostate cancer for active surveillance, detecting clinically significant cancer at baseline…

Eur J RadiolOct 7, 2026Read summary
Clinical ResearchPsychiatry

Effectiveness of psychosocial interventions addressing informal caregivers' mental health: an umbrella systematic review with 26,481 participants.

This umbrella systematic review and random-effects meta-analysis assessed psychosocial interventions for the mental health of informal caregivers, grouped by care recipients’ clinical conditions.

Clin Psychol RevOct 7, 2026Read summary
Clinical ResearchNeurology

Challenging historical associations and reassuring women: an updated meta-analysis of multiple sclerosis relapse risk following assisted reproductive technology.

This systematic review and random-effects meta-analysis examined whether assisted reproductive technology (ART) is associated with multiple sclerosis (MS) relapses in women with MS or incident MS in previously healthy…

Mult Scler Relat DisordOct 7, 2026Read summary
Clinical ResearchNephrology

The effects of exercise on pulmonary function and respiratory muscle strength in patients with chronic kidney disease: a systematic review and meta-analysis.

This systematic review and meta-analysis examined experimental studies of exercise and respiratory outcomes in people with chronic kidney disease across disease stages. Thirteen studies contributed to the meta-analyses.

Respir MedOct 7, 2026Read summary
Clinical ResearchUrology

Digital health technologies for the prevention and management of urinary tract infections in menopausal women: A systematic review.

This systematic review synthesised evidence on digital technologies for preventing or managing urinary tract infections in menopausal women.

MaturitasOct 7, 2026Read summary
Clinical ResearchOncology (Medical)

Neoadjuvant niraparib monotherapy for unresectable, homologous recombination deficiency-positive, high-grade serous ovarian cancer (NANT): a multicentre, single-arm, phase 2 trial.

This multicentre, single-arm phase 2 trial evaluated two cycles of neoadjuvant niraparib monotherapy in treatment-naïve patients with HRD-positive, advanced high-grade serous or endometrioid ovarian cancer considered…

Lancet OncolOct 7, 2026Read summary
Case ReportCardiology

Anterior ST-Segment Elevation Myocardial Infarction With Coronary Thrombosis in a Young Man with Newly Diagnosed HIV Infection and Pneumocystis jirovecii Pneumonia.

A 36-year-old man with newly diagnosed, severely immunosuppressive HIV infection and Pneumocystis jirovecii pneumonia developed an acute anterior ST-segment elevation myocardial infarction 25 days after starting…

Turk Kardiyol Dern ArsOct 7, 2026Read case
Clinical ResearchNephrology

Skeletal muscle adaptation to home-based exercise in chronic kidney disease.

This randomized controlled trial examined skeletal muscle responses to a 12-week, personalized home-based exercise program in 25 people with stage 3–5 chronic kidney disease (19 assigned to exercise and 6 to usual…

Am J Physiol Renal PhysiolOct 7, 2026Read summary
Clinical ResearchCardiothoracic Surgery

Effect of preoperative video-based digital educational program on incidence of delirium and length of hospital stay following coronary artery bypass grafting: A randomized controlled trial.

This parallel-group randomized controlled trial evaluated whether adding an 8-minute Arabic video-based educational program to standard preoperative education affected delirium and hospital stay after elective…

Heart LungOct 7, 2026Read summary
Clinical ResearchCardiology

Acute effects of volume-matched isometric exercise intensity on vascular function and autonomic regulation in men with elevated blood pressure.

This randomized controlled trial examined the acute effects of high-intensity isometric exercise (HIIE) versus low-intensity isometric exercise (LIIE) on cardiovascular function in 17 men with elevated blood pressure.

Clin Physiol Funct ImagingOct 6, 2026Read summary
Clinical ResearchHematologyOpen access

Infection burden in mismatched unrelated donor hematopoietic cell transplantation: results from the ACCESS trial.

The ACCESS trial evaluated infection burden in 268 adult patients undergoing HLA-mismatched unrelated donor hematopoietic cell transplantation (HCT) with posttransplant cyclophosphamide (PTCy) for graft-versus-host…

Blood AdvOct 6, 2026Read summary
Clinical ResearchPathology (Anatomic & Clinical)

Artificial intelligence-powered renal pathology for glomerular disease classification: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the performance of artificial intelligence (AI) models in classifying glomerular diseases using pathology images.

Ren FailOct 6, 2026Read summary
Clinical ResearchNephrology

Efficacy and safety of roxadustat for the treatment of renal anemia in patients undergoing peritoneal dialysis: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the efficacy and safety of roxadustat for treating renal anemia in patients undergoing peritoneal dialysis.

Ren FailOct 6, 2026Read summary
Clinical ResearchPsychiatry

Randomised controlled trial of fluoxetine versus naltrexone in compulsive sexual behaviour disorder.

This randomized controlled trial compared the efficacy and tolerability of fluoxetine and naltrexone in 80 participants with compulsive sexual behaviour disorder (CSBD).

BMJ Ment HealthOct 6, 2026Read summary
Case ReportGastroenterology

Approach to management of walled-off necrosis secondary to trauma-induced pancreatitis in a limited-resource setting.

A patient with trauma-induced pancreatitis developed a walled-off necrosis (WON) characterized by a necrotic peripancreatic collection. Imaging revealed a mature collection with necrotic debris.

BMJ Case RepOct 6, 2026Read case
Case ReportOncology (Medical)

Immune-related colitis following head and neck reconstructive surgery in a patient receiving long-term nivolumab.

A man with gastric cancer, receiving long-term nivolumab and prednisolone for immune-related myositis, underwent subtotal glossectomy for advanced tongue cancer. On postoperative day 4, he developed grade 3 diarrhoea.

BMJ Case RepOct 6, 2026Read case

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