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1616 articles

October 202624

Clinical ResearchOrthopedic SurgeryOpen access

Robotic-assisted conversion of unicompartmental to total knee arthroplasty: a systematic review.

This PRISMA-guided systematic review assessed robotic-assisted conversion of unicompartmental knee arthroplasty (UKA) to total knee arthroplasty (TKA).

J Robot SurgOct 15, 2026Read summary
Clinical ResearchCardiologyOpen access

Immune checkpoint inhibitor-related myocarditis, myositis, and myasthenia gravis overlap syndrome: a single-center case series and systematic review.

The aim of our study was to evaluate the clinical, diagnostic, therapeutic, and prognostic features of immune checkpoint inhibitor-related myocarditis, myositis, and myasthenia gravis overlap syndrome (IM3OS).

Support Care CancerOct 15, 2026Read summary
Clinical ResearchPediatricsOpen access

Comparison of fecal continence and bowel function scoring systems following anorectal malformation repair: a systematic review.

This systematic review assessed whether fecal continence and bowel function scoring systems give comparable results when applied to the same cohorts after anorectal malformation repair.

Pediatr Surg IntOct 15, 2026Read summary
Case ReportGeneral Surgery

3D-printed reduction guide with hinge and window. Design for conservative veneer preparations.

A 36-year-old woman sought improvement of her smile. Existing ceramic veneers from the maxillary right to left canine showed staining and crack lines, with mild gingival recession around the restored teeth.

Int J Esthet DentOct 15, 2026Read case
Case ReportGeneral Surgery

Micro-layering technique for esthetic rehabilitation. A case report.

A male patient sought esthetic rehabilitation for a diastema between the central incisors, mismatched tooth shapes, and overall dental disharmony.

Int J Esthet DentOct 15, 2026Read case
Clinical ResearchPsychiatry

Artificial intelligence EEG biomarkers for schizophrenia diagnosis: Systematic review with PROBAST+AI assessment.

This systematic review assessed the diagnostic performance and methodological quality of AI models using resting-state EEG to identify schizophrenia or first-episode psychosis.

Eur PsychiatryOct 15, 2026Read summary
Clinical ResearchHematology

TRANSFORM-1 phase 3 study: efficacy and safety of navitoclax plus ruxolitinib in patients with untreated myelofibrosis.

TRANSFORM-1 was a multicentre, randomised phase 3 trial comparing navitoclax plus ruxolitinib with placebo plus ruxolitinib in Janus kinase inhibitor-naïve adults with intermediate-2 or high-risk myelofibrosis.

BloodOct 15, 2026Read summary
Clinical ResearchHematology

A phase 2 trial of daratumumab monotherapy for patients with newly diagnosed cardiac stage IIIb AL amyloidosis.

This prospective, multicentre phase 2 trial evaluated daratumumab monotherapy in previously untreated patients with measurable AL amyloidosis and advanced cardiac stage IIIB disease; patients with inadequate response…

BloodOct 15, 2026Read summary
Clinical ResearchNeurology

Key Predictors of Cerebral Vasospasm Following Subarachnoid Hemorrhage: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis examined observational evidence on factors associated with cerebral vasospasm after subarachnoid hemorrhage (SAH).

West J Nurs ResOct 15, 2026Read summary
Clinical ResearchGeriatricsOpen access

Body weight following a multidomain lifestyle intervention in older adults at risk of dementia - A post-hoc analysis of the AgeWell.de-trial.

This post-hoc analysis of the cluster-randomized AgeWell.de trial examined body weight in 678 adults aged 60–77 years with overweight or obesity and at risk for dementia.

BMC GeriatrOct 15, 2026Read summary
Clinical ResearchPediatrics

A Systematic Review of Screen Time and Obesity in Children, Adolescents, and Young Adults: Sex-Specific Pathways and Implications for Public Health Interventions.

This systematic review synthesized evidence on screen time and obesity-related outcomes in children, adolescents, and young adults, examining possible sex-specific patterns.

Prev Chronic DisOct 15, 2026Read summary
Clinical ResearchPsychiatryOpen access

Assessing the Impact of Metacognitive Therapy on OCD Severity and Beliefs: A Three-Wave Multisite RCT With Panel Mediation Analysis.

This multisite, assessor-blinded randomized controlled trial compared 12 weekly sessions of individual metacognitive therapy (MCT) with documented treatment as usual (TAU) in 76 adults with OCD receiving outpatient care…

Depress AnxietyOct 15, 2026Read summary
Case ReportDermatologyOpen access

Focal Epithelial Hyperplasia in a Somali Child: A Case Report and Review of Management with Topical Imiquimod.

An 8-year-old Somali girl had a 3.5-year history of asymptomatic, progressively increasing oral lesions. Examination showed multiple soft, flat-topped verrucous papules on the lower labial, buccal and lingual mucosa and…

Int Med Case Rep JOct 15, 2026Read case
Case ReportCardiothoracic SurgeryOpen access

Optimization of Anticoagulation Strategy During Cardiopulmonary Bypass in Neonates with Congenital Heart Disease: A Randomized Controlled Trial.

Neonatal hemostatic immaturity complicates anticoagulation during cardiopulmonary bypass (CPB). Current practice largely follows the strategy of 400 U/kg from adult protocols, as neonatal-specific guidelines and…

Drug Des Devel TherOct 15, 2026Read case
Case ReportPediatricsOpen access

Giant Cystic Lymphangioma of the Transverse Mesocolon in a 7-Year-Old Child: A Case Report.

A 7-year-old girl presented with several weeks of vomiting, abdominal pain and progressive distension. Examination found a large abdominal mass; laboratory results were unremarkable.

Int Med Case Rep JOct 15, 2026Read case
Case ReportNeurosurgery

Inside a Programmer's Brain: Dissociating Code and Language Comprehension Networks Using a Novel fMRI-ESM Protocol.

A professional software engineer with an IDH-mutant astrocytoma in the left middle frontal gyrus underwent preoperative fMRI and intraoperative electrical stimulation mapping (ESM) to assess both language and code…

Hum Brain MappOct 15, 2026Read case
Clinical ResearchNeurologyOpen access

Symptom improvement with dosing above 9 g of low-sodium oxybate: effectiveness and safety in participants with narcolepsy in the DUET study.

This prospective, multicohort, open-label study evaluated effectiveness and safety of low-sodium oxybate (LXB) doses above 9 g/night in participants with narcolepsy type 1 or 2 who were already taking 9 g/night.

J Clin Sleep MedOct 15, 2026Read summary
Clinical ResearchNeurosurgery

Effect of Previsit AI-Generated Document Summaries on Consultation Time and Patient-Physician Communication - The AI-INFOCARE Randomized Controlled Trial.

This single-center randomized controlled trial evaluated whether a quality-checked, AI-generated lay summary of medical findings before outpatient neurosurgical consultations affected communication and consultation…

NEJM AIOct 15, 2026Read summary
Case ReportCardiology

Very Young ST-Segment Elevation Myocardial Infarction Associated With Chronic Nonmedical Anabolic-Androgenic Steroid Use: A Case Report.

A 29-year-old man with no known medical history and approximately two years of nonmedical testosterone and stanozolol use presented with acute chest pain and anterior ST-segment elevation myocardial infarction.

Turk Kardiyol Dern ArsOct 15, 2026Read case
Clinical ResearchCardiology

Efficacy and Safety of Enlicitide in Hypercholesterolemia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

This systematic review and random-effects meta-analysis assessed efficacy and safety of oral enlicitide in adults with hypercholesterolemia.

Endocrinol Diabetes MetabOct 14, 2026Read summary
Clinical ResearchGastroenterology

Safety, Tolerability and Antiviral Activity of GST-HG131 in Chronic Hepatitis B: A Randomized, Double-Blind Phase IIa Study.

This randomized, double-blind, placebo-controlled Phase IIa trial assessed oral GST-HG131 in 45 adults with chronic hepatitis B receiving nucleos(t)ide analogue monotherapy.

Liver IntOct 14, 2026Read summary
Clinical ResearchPsychiatry

The psychological experience of body image change in adult stoma patients: A systematic review and qualitative meta-synthesis.

This systematic review and qualitative meta-ethnography synthesised English-language qualitative research on body image change in adults with a stoma. Eighteen studies involving 602 participants were included.

Br J Health PsycholOct 14, 2026Read summary
Clinical ResearchPsychiatry

An Internet-Based Cognitive-Behavioral Program, With Telephone Support, Improves Pain, Disability and Emotional Well-Being in Adults With Chronic Pain: Randomized Controlled Trial of the Pain Course With 2-Year Follow-Up.

This randomised controlled trial evaluated an internet-delivered, cognitive-behavioral Pain Course with clinician support in adults with chronic pain living in Ireland.

Clin J PainOct 14, 2026Read summary
Clinical ResearchAnesthesiology

Pericapsular Nerve Group Block Versus Femoral Nerve Block for Analgesia in Newly Admitted Patients With Hip Fractures: A Randomized Controlled Trial.

This randomized controlled trial compared preoperative pericapsular nerve group (PENG) block with femoral nerve block (FNB) in 60 newly admitted patients with hip fractures.

Clin J PainOct 14, 2026Read summary

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