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497 articles
September 202624
Durable disease control following multidisciplinary treatment including pembrolizumab in POLE-mutated dedifferentiated endometrial carcinoma with brain metastases: A case report.
A 58-year-old woman with POLE-mutated dedifferentiated endometrial carcinoma presented with headache, dizziness, and weakness due to multiple brain and pulmonary metastases.
Primary laryngeal paraganglioma with multisystem metastases: A case report.
A patient with laryngeal paraganglioma presented with progressive dysphagia, hoarseness, and dyspnea. Imaging revealed a laryngeal mass, confirmed by histopathology.
Meta-analysis of PAX1/JAM3 methylation performance in high-risk HPV-positive women.
This meta-analysis evaluated the diagnostic performance of PAX1/JAM3 dual-gene methylation testing in high-risk HPV-positive women for detecting high-grade cervical intraepithelial neoplasia (CIN) and cervical cancer.
Helcococcus kunzii as a rare etiological agent of spondylodiscitis partially managed with oral antibiotic therapy in a patient with diabetes mellitus: a case report.
A 62-year-old man with type 1 diabetes mellitus presented with severe lumbar pain, leading to a diagnosis of spondylodiscitis confirmed by MRI.
Fatal Cutaneous Mucormycosis Initially Misdiagnosed as Necrotizing Fasciitis in an Uncontrolled Diabetic Patient: A Case Report Highlighting Diagnostic Delay.
A 64-year-old male with undiagnosed diabetes presented with altered consciousness and extensive necrotic lesions, initially diagnosed as bacterial necrotizing fasciitis.
Death due to intentional consumption/ingestion of caffeine powder: A case report of the forensic and toxicological evaluation of caffeine intoxication.
A man in his late twenties presented with nausea, vomiting, and tachycardia after intentionally ingesting a high dose of powdered caffeine.
Non-Meningothelial Mesenchymal Tumor of the Central Nervous System: Case Report and Literature Review.
A 40-year-old man presented with progressive left-sided paresthesia, leading to the discovery of a supratentorial non-meningothelial mesenchymal tumor (NMMT) via neuroimaging, which revealed a parasagittal mass.
Primary NTRK-rearranged spindle cell sarcoma of the colon with ETV6-NTRK3 fusion.
A man in his late 30s presented with abdominal pain, leading to a CT scan that revealed a large transmural tumor in the colon. The multidisciplinary team opted for immediate surgery without preoperative colonoscopy.
Orbital lymphoma presenting as preseptal cellulitis in a child with ataxia-telangiectasia.
A young child with ataxia-telangiectasia presented with left periorbital swelling, initially treated as a periorbital infection.
Highly viscous ascites prompting reconsideration of cardiorenal syndrome in a patient with advanced CKD after TAVI.
An elderly man with advanced chronic kidney disease and cardiovascular issues developed refractory pleural effusion, ascites, and peripheral edema following transcatheter aortic valve implantation.
Successful hemodialysis withdrawal with glucocorticoid treatment after achieving infection control in a case of crescentic IgA-dominant staphylococcus-associated glomerulonephritis.
A 70-year-old woman presented with bacteremia and multiple abscesses due to methicillin-susceptible Staphylococcus aureus, leading to acute kidney injury and the need for hemodialysis.
Déjà vu.
A male in his mid-20s presented with fever, purpuric rash, neuropathy, marked eosinophilia, hepatic dysfunction, and extensive multisystem thrombosis.
Radiologically occult nasopharyngeal carcinoma: the importance of clinical suspicion and repeat biopsy.
A man in his 40s, previously diagnosed with a left-sided nasopharyngeal lesion, returned with aural fullness and tinnitus. Flexible nasendoscopy revealed subtle changes at the left eustachian tube orifice, but MRI…
Congenital infantile fibrosarcoma of the foot.
A newborn boy presented with a smooth mass measuring approximately 4 cm on the sole of his right foot, initially suspected to be an atypical haemangioma.
Cryptococcal meningitis with cerebrospinal fluid human immunodeficiency virus escape presenting as transient diplopia and areflexia.
A man in his early 40s with stable HIV on antiretroviral therapy presented with transient binocular diplopia and areflexia.
Clinical Perspective on Exophiala dermatitidis, A Systematic Review of Cases Reported Globally over 36 Years.
This systematic review analyzed 77 reported cases of Exophiala dermatitidis infections from 1989 to 2024, highlighting a rise in cases, particularly since 2010.
Postoperative ctDNA-Guided Adjuvant Therapy in Resected Colorectal Cancer: A Systematic Review and Meta-analysis of Prognostic Validity Versus Treatment-Decision Utility.
This systematic review and meta-analysis evaluated the prognostic validity and treatment-decision utility of postoperative circulating tumor DNA (ctDNA) in resected colorectal cancer.
Talimogene Laherparepvec Response in Recurrent Melanoma During Corticosteroid Replacement for Immune Checkpoint Inhibitor-Induced Adrenal Insufficiency: A Case Report.
A 78-year-old man with recurrent in-transit melanoma of the scalp developed secondary adrenal insufficiency after pembrolizumab therapy, necessitating chronic hydrocortisone replacement.
Maxillary brown tumour as the initial presentation of primary hyperparathyroidism.
A middle-aged woman presented with right cheek swelling due to an expansile maxillary lesion, initially misdiagnosed as a giant cell tumour.
Pheochromocytoma Masquerading as Acute Coronary Syndrome Complicated by Cardiogenic Shock: A CARE-Compliant Case Report.
A 59-year-old man with a history of intermittent chest tightness presented with acute cardiogenic shock, elevated troponin levels, and reduced left ventricular ejection fraction.
Induction FLOT Chemotherapy Prior to Neoadjuvant Chemoradiotherapy in the Treatment of Lower Esophageal and Proximal Gastric Adenocarcinoma: A Phase II, Single-Arm Clinical Trial.
This Phase II, single-arm clinical trial evaluated the effectiveness of induction FLOT chemotherapy followed by neoadjuvant chemoradiotherapy in patients with resectable distal esophageal and proximal gastric…
Resection of a symptomatic complex anterior mediastinal teratoma via sternotomy.
A patient presented with a large anterior mediastinal teratoma measuring 11 × 10 × 10 cm, causing significant compression of the right atrium, right ventricle, superior vena cava, and aorta, along with perforation into…
Tumoral and Systemic Immune Correlates of Response to Concurrent Pembrolizumab and Chemoradiotherapy in Patients with Resected High-Risk Head and Neck Squamous Cell Carcinoma.
This phase I clinical trial evaluated the safety and immune correlates of adjuvant pembrolizumab combined with chemoradiotherapy (CRT) in 34 patients with high-risk, HPV-negative head and neck squamous cell carcinoma.
Clinical and Genomic Insights into the Allodiploid Hybrid Pathogen Aspergillus latus: A Retrospective Case Series.
This case series describes five patients with infections caused by Aspergillus latus, identified through metagenomic next-generation sequencing (mNGS).
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