Trending archive
Every article that has appeared in Trending stays here. Search by title, journal, author or PMID, and narrow by date.
360 articles
June 20263
Incidence and risk factors of sepsis-associated delirium in the intensive care unit: a systematic review and meta-analysis.
This systematic review and meta-analysis examined the incidence and risk factors of sepsis-associated delirium (SAD) in ICU patients, analyzing data from 52 studies with 89,789 patients.
N-Ethylpentedrone: first hair detection and human metabolic profiling across multiple biological matrices using UHPLC-HRMS, molecular networking and in silico prediction.
A 29-year-old man was found deceased after using N-ethylpentedrone (NEP) in a chemsex context. Analysis of three bags containing NEP confirmed a purity above 98%.
Recurrent bradycardia and hypotension after Oral Lacosamide during hospital boarding in the emergency department: A case report.
A 79-year-old woman with a history of hypertension and seizure disorder presented with confusion and weakness after starting oral lacosamide.
May 202621
Nurse-Led Recognition of Occult Carbon Monoxide Poisoning Following a Minor Motor Vehicle Collision: A Case Report.
A family presented to the emergency department following a low-speed motor vehicle collision, initially exhibiting symptoms attributed to minor trauma.
Ketamine-based ICU sedation and patient-centered outcomes: A systematic review and meta-analysis of mechanical ventilation duration, ICU length of stay, and delirium.
This systematic review and meta-analysis evaluated the effects of ketamine-based sedation on ICU outcomes in 903 patients. It found that ketamine significantly reduced ICU length of stay (MD: -0.86; 95% CI: -1.51…
Effects of midazolam and propofol on EEG detection of epileptiform activity in patients with altered consciousness.
This multicenter randomized controlled trial assessed the effects of midazolam and propofol on EEG detection of epileptiform activity in 364 adult patients with altered consciousness.
Early vs delayed opioid administration for pediatric sickle cell vaso-occlusive crisis: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated early versus delayed opioid administration in pediatric patients with sickle cell vaso-occlusive episodes (VOE).
Eosinophilic vasculitis of aortic valve in EGPA: a life-threatening onset of disease.
A 51-year-old man with eosinophilic severe asthma and chronic rhinosinusitis presented with worsening dyspnea and cardiac arrest after two months of low-grade fever and malaise.
Effect of urinary catheter securement band on meatal pressure injury in male intensive care patients: A randomized controlled trial.
This randomized controlled trial evaluated the effectiveness of a urinary catheter securement band in preventing meatal pressure injury (meatal-PI) among 248 male ICU patients.
Accelerated Diagnostic Pathways for Suspected Acute Coronary Syndrome in Practice: A Randomized Trial of 0/1-Hour vs 0/3-Hour Troponin Testing.
This pragmatic randomized trial compared the 0/1-hour and 0/3-hour high-sensitivity troponin (hs-cTn) testing pathways for suspected acute coronary syndrome (ACS) in 3,543 patients across two emergency departments.
Evaluating the Effectiveness of an Intimate Partner Violence Training Intervention on Healthcare Providers' Preparedness, Knowledge, and Experiences: A Mixed-Methods Study From Nepal.
This randomized controlled trial in Nepal assessed the effectiveness of a 10-day training intervention on healthcare providers' preparedness and knowledge regarding intimate partner violence (IPV).
The effect of peripheral vasopressor protocols on extravasation rates: A systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the impact of peripheral vasopressor protocols on extravasation rates in critically ill patients.
Endovascular thrombectomy versus best medical therapy for acute vertebrobasilar artery occlusion in patients with low NIHSS scores: a meta-analysis.
This meta-analysis evaluated the effectiveness of endovascular thrombectomy (EVT) versus best medical therapy (BMT) in patients with acute vertebrobasilar artery occlusion and mild symptoms (NIHSS score ≤10).
Intravenous Magnesium Sulfate for Acute Nontraumatic Headache in the Emergency Department.
This randomized controlled trial evaluated the efficacy of intravenous magnesium sulfate (MgSO4) combined with paracetamol in adults with acute nontraumatic headache.
Type, severity, frequency and management of adverse reactions associated with ultrasound contrast agents: a systematic review and meta-analysis.
This systematic review and meta-analysis evaluated the incidence of adverse drug reactions (ADRs) associated with ultrasound contrast agents (UCAs) in over 1 million adults and 36,000 children.
Systematic Review of Pediatric Ketamine in Emergency Department Procedural Sedation: Frequency and Predictors of Adverse Events.
This systematic review analyzed 20 studies involving 58,752 children to assess the frequency of adverse events associated with intravenous ketamine sedation in pediatric emergency departments.
SGLT-2 Use and Hypoglycemic Ketoacidosis.
A patient presented with severe hypoglycemic nondiabetic ketoacidosis, a rare variant of diabetic ketoacidosis. The diagnostic challenge arose due to the absence of hyperglycemia, which is typically expected in such…
From Negative Duplex to Phlegmasia in Minutes: Bedside POCUS Identifies Rapid Thrombosis Unmasking Underlying May-Thurner Syndrome.
A 50-year-old female presented with left leg swelling after hospitalization for ulcerative colitis. Initial duplex ultrasound was negative for DVT, but a subsequent point-of-care ultrasound (POCUS) revealed a rapidly…
Venom with an altitude: Coagulopathy following an envenomation by the high-mountain snake Gloydius monticola (Likiang pitviper) in Yunnan Province, China.
A 34-year-old male experienced a severe envenomation after being bitten by a Likiang pitviper (Gloydius monticola) at an elevation of 3500 m.
Prospective evaluation of patient recognition of emergency clinician roles and an intervention to improve recognition.
This prospective controlled trial evaluated clinician role misidentification among 145 emergency department patients. An educational intervention improved correct identification from 40.0% to 64.0% (p = 0.005).
Single-step versus multi-step intranasal naloxone devices for overdose response: A randomized usability study in an at-risk population.
This randomized usability study evaluated single-step versus multi-step intranasal naloxone devices among 40 participants without prior training in an urban emergency department.
Prehospital identification of hypoglycemia-induced seizure using a smartphone-linked continuous glucose monitoring application.
A 37-year-old man with type 1 diabetes experienced a generalized tonic-clonic seizure while shopping. His son used a smartphone app linked to the patient's continuous glucose monitoring (CGM) device to identify a…
Early vasopressin administration in septic shock: A systematic review, meta-analysis, and multicenter retrospective observational study.
This study evaluated the timing of vasopressin initiation in septic shock through a multicenter registry analysis and a systematic review with meta-analysis.
Mothership and Drip-and-Ship Strategies in Mechanical Thrombectomy for Acute Ischemic Stroke.
This systematic review and meta-analysis evaluated the effectiveness of mothership versus drip-and-ship strategies for acute ischemic stroke due to large vascular occlusion in 25,005 patients.
Stay updated for free
Get the 3 most interesting publications in one specialty each week.
Weekly email. Unsubscribe anytime.
Want this personalized?
Stop searching the literature. Choose what you follow and xxcode will build your personalized medical digest.
- Your specialties
- Your filters and thresholds
- Clinical Research + Case Reports, tuned separately
- Automatic weekly delivery
- Audio and text
Prefer listening? Personalized audio digests are available with Pro.