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433 articles

June 202623

Clinical ResearchInternal Medicine (General)Open access

Environmental Burden of Lead and Public Health Issues in Nigeria: A Systematic Review of Emerging Evidence.

This systematic review examined the environmental burden of lead exposure in Nigeria, highlighting severe contamination in artisanal mining areas and urban centers.

Biol Trace Elem ResJun 15, 2026Read summary
Case ReportHematology

PROS1 Cys475Tyr mutation associated with a type III protein S deficiency pattern.

A 35-year-old woman with a history of deep vein thrombosis was diagnosed with protein S deficiency. After initial treatment with parenteral anticoagulation, she transitioned to a direct oral anticoagulant.

Blood Coagul FibrinolysisJun 15, 2026Read case
Clinical ResearchHematologyOpen access

Safety and Effectiveness of Direct Oral Anticoagulants Versus Low-Molecular-Weight Heparin for Cancer-Associated Thrombosis: A Systematic Review and Meta-analysis.

This systematic review and meta-analysis compared the safety and effectiveness of direct oral anticoagulants (DOACs) versus low-molecular-weight heparin (LMWH) in patients with cancer-associated thrombosis.

Drug SafJun 15, 2026Read summary
Clinical ResearchHematology

Asymptomatic atrial fibrillation in patients treated with BTK inhibitors in hematologic malignancies: a systematic review and metanalysis.

This systematic review and meta-analysis evaluated the prevalence of asymptomatic atrial fibrillation (AF) in patients with hematologic malignancies undergoing Bruton's tyrosine kinase inhibitor (BTKi) therapy.

Eur J Intern MedJun 15, 2026Read summary
Clinical ResearchHematologyOpen access

Second Primary Malignancies in Patients With B-Cell Lymphomas Treated With Bruton's Tyrosine Kinase Inhibitors: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated the incidence of second primary malignancies (SPMs) in 9337 patients with B-cell lymphomas treated with Bruton's tyrosine kinase (BTK) inhibitors.

Eur J HaematolJun 14, 2026Read summary
Clinical ResearchHematology

Erythroferrone in β-thalassemia: Systematic review and meta-analysis.

This systematic review and meta-analysis evaluated erythroferrone (ERFE) levels in patients with β-thalassemia, analyzing data from 13 studies involving 975 patients.

Clin Chim ActaJun 12, 2026Read summary
Clinical ResearchInfectious DiseasesOpen access

Efficacy and safety of maribavir in Japanese patients with post-transplant cytomegalovirus infections: a phase III study.

This phase III, multicenter study evaluated the efficacy and safety of maribavir in Japanese patients aged ≥16 years with cytomegalovirus (CMV) infections post-transplant.

Int J HematolJun 12, 2026Read summary
Clinical ResearchHematologyOpen access

Indirect Comparison of the Efficacy of Zanubrutinib vs Ibrutinib and Acalabrutinib in Treatment-Naive Chronic Lymphocytic Leukemia: 6-Year Follow-Up.

This comparative study evaluated the efficacy of zanubrutinib versus ibrutinib and acalabrutinib in treatment-naive chronic lymphocytic leukemia (CLL) over a 6-year follow-up.

Adv TherJun 11, 2026Read summary
Case ReportDermatology

Skin Lesion Reconstruction in Graft Versus Host Disease Using Autograft From the Bone Marrow Donor Panniculectomy Tissue.

A pediatric patient with a history of Ph-like B-cell acute lymphoblastic leukemia developed chronic graft-versus-host disease (cGVHD) affecting the skin after a haploidentical bone marrow transplant.

Ann Plast SurgJun 11, 2026Read case
Clinical ResearchHematology

Exa-cel in Children with Transfusion-Dependent β-Thalassemia or Sickle Cell Disease.

This phase 3 clinical trial evaluated exa-cel, a cell therapy, in children aged 5 to 11 with transfusion-dependent β-thalassemia or sickle cell disease.

N Engl J MedJun 11, 2026Read summary
Case ReportInfectious Diseases

Anti-interferon-γ autoantibody syndrome mimicking lymphoproliferative disorders: a case series.

Two patients presented with prolonged fever, weight loss, and generalized lymphadenopathy, initially misdiagnosed as lymphoproliferative disorders based on lymph node biopsies suggesting multicentric Castleman disease…

Int J Infect DisJun 10, 2026Read case
Clinical ResearchHematologyOpen access

The Effect of Diet and Dietary Supplements on Iron Status of Active Females: A Systematic Review and Meta-analysis of Interventional Trials.

This systematic review and meta-analysis evaluated the impact of dietary interventions on iron status in active females of reproductive age.

Sports MedJun 10, 2026Read summary
Case ReportPathology (Anatomic & Clinical)

Case Series of Cutaneous Rothia Mucilaginosa Infection and an Important Potential Pitfall Case.

Three immunocompromised patients with hematolymphoid malignancies and profound neutropenia presented with suspected cutaneous infections caused by Rothia mucilaginosa.

Am J DermatopatholJun 9, 2026Read case
Case ReportHematologyOpen access

Calciphylaxis complicated by NDM-1-producing Pseudomonas aeruginosa: first experience with cefepime-zidebactam alongside phage therapy in the USA.

A young woman with acute myeloid leukaemia presented with calciphylaxis, characterized by arteriolar calcification and ischemic skin necrosis.

Lancet Infect DisJun 9, 2026Read case
Case ReportDermatology

Clinicopathological Challenge: A Rapidly Progressive Bullous Ulcer in a Patient Receiving Gilteritinib.

An 80-year-old woman with therapy-related acute myeloid leukemia developed a painful violaceous papulonodule on her right shin five months after starting gilteritinib.

Int J DermatolJun 9, 2026Read case
Clinical ResearchHematology

Use of extracellular vesicles as a therapeutic option for graft-versus-host disease: systematic review of in vivo studies.

This systematic review evaluated the therapeutic potential of extracellular vesicles (EVs) in animal models of graft-versus-host disease (GVHD).

Int ImmunopharmacolJun 8, 2026Read summary
Case ReportHematology

Alpha-2 antiplasmin deficiency: a rare fibrinolytic disorder identified after decades of diagnostic delay.

A woman presented with decades of postoperative bleeding and transfusion dependence, initially misdiagnosed with von Willebrand disease.

Blood Coagul FibrinolysisJun 8, 2026Read case
Clinical ResearchHematologyOpen access

Longitudinal Neurocognitive Changes for Patients With Hematologic Malignancies Undergoing Hematopoietic Stem Cell Transplantation: A Systematic Review With Structured Narrative Synthesis.

This systematic review evaluated longitudinal neurocognitive changes in patients with hematologic malignancies undergoing hematopoietic stem cell transplantation (HSCT).

Eur J HaematolJun 7, 2026Read summary
Clinical ResearchDermatologyOpen access

Is tattooing associated with an increased risk of cancer? A systematic review and meta-analysis.

This systematic review and meta-analysis assessed whether tattoo exposure was associated with skin cancer or hematological malignancies in adults, pooling seven observational studies with 140,841 participants.

Clin Transl OncolJun 6, 2026Read summary
Clinical ResearchCardiology

Management of anticoagulation in patients with heparin-induced thrombocytopenia requiring cardiac surgery with cardiopulmonary bypass: guidance from the ISTH SSC on Perioperative and Critical Care Haemostasis and Thrombosis.

This systematic review evaluated anticoagulation strategies for patients with heparin-induced thrombocytopenia (HIT) undergoing cardiac surgery with cardiopulmonary bypass.

J Thromb HaemostJun 4, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Evaluation of ex-utero collection for umbilical cord blood banking: A randomized clinical trial comparing cord blood quality with the in-utero technique.

This prospective, unblinded randomized clinical trial compared ex-utero with standard in-utero umbilical cord blood collection among pregnant women at a Barcelona hospital and cord blood program.

Int J Gynaecol ObstetJun 4, 2026Read summary
Clinical ResearchOphthalmology

Orbital involvement in sickle cell disease: A systematic review.

This systematic review analyzed 76 cases of orbital involvement in sickle cell disease (SCD) from 53 studies. Predominantly affecting males with an average age of 13.2 years, the review highlighted that 6.6% presented…

Surv OphthalmolJun 3, 2026Read summary
Clinical ResearchHematology

Acquired ring chromosomes in hematological malignancies: A systematic evidence review for diagnostic advances, cytogenomic insights, and clinical significance by an International Consortium on Human Ring Chromosomes (ICHRC) working group.

This systematic review by the International Consortium on Human Ring Chromosomes (ICHRC) examines acquired ring chromosomes (aRCs) in hematological malignancies.

Cancer GenetJun 1, 2026Read summary

May 20261

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