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353 articles

March 202611

Clinical ResearchOphthalmology

The efficacy and safety of reducing intraocular pressure to single-digit levels in Normal-tension glaucoma: A systematic review and meta-analysis.

This systematic review and meta-analysis assessed whether lowering intraocular pressure (IOP) to single-digit levels benefits treated patients with progressive normal-tension glaucoma.

Acta OphthalmolMar 20, 2026Read summary
Case ReportOphthalmology

Epithelial Downgrowth Mimicking Recurrent Retroprosthetic Membrane After Boston Keratoprosthesis Implantation.

A 74-year-old monocular man with prior penetrating corneal injury, multiple failed corneal transplants, and a Boston type 1 keratoprosthesis developed reduced vision and opaque material behind the device’s optical…

CorneaMar 18, 2026Read case
Clinical ResearchOphthalmology

Systematic Literature Review on the Effect of Cenegermin on Corneal Sensation and Innervation in Patients with Neurotrophic Keratopathy.

This systematic literature review assessed changes in corneal sensation (CS) and corneal innervation (CI) after cenegermin treatment in patients with neurotrophic keratopathy (NK).

J Ocul Pharmacol TherMar 18, 2026Read summary
Clinical ResearchOphthalmology

Beyond keratoplasty: The role of Descemet stripping only in the management of Fuchs endothelial dystrophy-a systematic review and meta-analysis.

This systematic review and meta-analysis assessed Descemet stripping only (DSO) for Fuchs endothelial corneal dystrophy (FECD), including prospective and retrospective clinical series with at least 5 patients and 6…

Surv OphthalmolMar 17, 2026Read summary
Case ReportOphthalmology

Drusenoid macular dystrophies in Singaporean Chinese: first report of Doyne honeycomb retinal dystrophy and late-onset retinal degeneration from Southeast Asia.

We report two ethnic Chinese families affected by distinct drusenoid inherited maculopathies: Doyne Honeycomb Retinal Dystrophy (DHRD) and Late-Onset Retinal Degeneration (L-ORD)-to expand their recognized phenotypic…

Ophthalmic GenetMar 15, 2026Read case
Clinical ResearchOphthalmology

Photodynamic therapy and anti-vascular endothelial growth factor for acute central serous chorioretinopathy: An updated systematic review and meta-analysis.

This PRISMA-compliant systematic review and meta-analysis compared photodynamic therapy (PDT) and anti-vascular endothelial growth factor (anti-VEGF) treatment with observation for acute central serous chorioretinopathy…

Surv OphthalmolMar 14, 2026Read summary
Clinical ResearchOphthalmology

Lidocaine gel provides superior analgesia compared to oxybuprocaine drops in pterygium surgery: A double-masked randomized trial.

This double-masked randomized trial compared topical 2% lidocaine gel with 0.4% oxybuprocaine drops for anesthesia during pterygium surgery in adults with bilateral primary nasal pterygia.

Eur J OphthalmolMar 10, 2026Read summary
Clinical ResearchOncology (Medical)Open access

What is the incidence and clinical significance of dry eye disease in patients treated with immune checkpoint inhibitors? A systematic review and meta-analysis of ocular immune-related adverse events.

This systematic review and meta-analysis assessed dry eye disease (DED) in adults treated with immune checkpoint inhibitors (ICIs), drawing on 13 studies.

Acta OphthalmolMar 9, 2026Read summary
Clinical ResearchOphthalmology

Efficacy and safety of conbercept, ranibizumab and laser in retinopathy of prematurity: A systematic review and network meta-analysis.

This systematic review and network meta-analysis compared conbercept, ranibizumab, and laser therapy for retinopathy of prematurity across 53 studies involving 8787 eyes.

Surv OphthalmolMar 7, 2026Read summary
Clinical ResearchOphthalmologyOpen access

Prenatal and childhood exposure to smoking and retinal nerve fibre layer thickness: A meta-analysis of three independent birth cohorts.

This meta-analysis combined optical coherence tomography data from three independent Danish and Australian birth cohorts to assess retinal nerve fibre layer (RNFL) thickness in relation to prenatal and childhood smoking…

Acta OphthalmolMar 7, 2026Read summary
Case ReportOphthalmology

Cultured Human Corneal Endothelial Cell Injection (Vyznova) in Eyes with Extremely Low Intraocular Pressure After Glaucoma Surgery: Case Reports.

Two patients with bullous keratopathy and intraocular pressure (IOP) of ≤4 mm Hg after glaucoma-filtering surgery received cultured human corneal endothelial cell (cHCEC) injection with Vyznova.

CorneaMar 6, 2026Read case

February 20268

Clinical ResearchNeurosurgery

Surgical Management of Optic Pathway-Hypothalamic Gliomas: Institutional Experience and Systematic Review.

This retrospective institutional series and systematic review examined surgical outcomes for optic pathway-hypothalamic gliomas (OPHGs).

Oper NeurosurgFeb 18, 2026Read summary
Clinical ResearchOphthalmologyOpen access

Non-physician delivered intravitreal injection service: A systematic review of safety, implementation, training and patient experience.

This systematic review assessed the safety, implementation, training and patient experience of intravitreal anti-VEGF injections delivered by non-physician healthcare professionals.

Acta OphthalmolFeb 11, 2026Read summary
Clinical ResearchOphthalmology

Sharper than human eyes? A systematic review and meta-analysis of machine learning for retinal detachment detection.

This diagnostic test accuracy systematic review and meta-analysis assessed machine-learning methods for detecting retinal detachment across imaging modalities. The authors included 20 studies and analysed 69 models.

Eur J OphthalmolFeb 10, 2026Read summary
Case ReportOphthalmology

Atypical Cogan's Syndrome Is Common among Japanese Patients: A Case Report and Literature Review in Japan.

A 55-year-old Japanese woman presented with fever, headache, vertigo, sensorineural hearing loss, and scleritis. These findings led to a diagnosis of Cogan’s syndrome.

Intern MedFeb 10, 2026Read case
Clinical ResearchOphthalmology

Outer nuclear layer hyperreflectivity as an optical coherence tomography finding in Danon disease.

To describe an optical coherence tomography (OCT) finding that is highly prevalent in Danon disease.

Acta OphthalmolFeb 10, 2026Read summary
Case ReportEmergency Medicine

Subcutaneous and Orbital Emphysema With Pneumocephalus Secondary to Compressed-Air Gun Injury to the Face.

A healthy 26-year-old man presented with right periorbital swelling and headache after compressed air struck his face while he was cleaning work clothes with an air gun.

Am J Forensic Med PatholFeb 5, 2026Read case
Case ReportOphthalmology

Monocular elevation deficiency associated ptosis misdiagnosed as simple congenital ptosis: management with Müller Muscle-Conjunctival Resection.

A 14-year-old girl referred with presumed congenital ptosis was found on ophthalmic examination to have marked right-eye elevation restriction in all gaze positions and mild hypotropia, consistent with monocular…

StrabismusFeb 2, 2026Read case
Clinical ResearchOphthalmology

Adherence of glaucoma intervention studies to World Glaucoma Association guidelines.

This systematic review assessed how well published glaucoma surgical and laser studies followed World Glaucoma Association (WGA) reporting guidelines.

Acta OphthalmolFeb 2, 2026Read summary

January 20265

Clinical ResearchOphthalmology

A prospective randomized pilot study comparing fibrin glue, buried suture knot and exposed suture knot techniques for conjunctival closure in bilateral symmetrical fornix approach squint surgery.

This prospective randomized pilot study compared fibrin glue (FG), buried suture knot (BSK), and exposed suture knot (ESK) for conjunctival closure in patients over 10 years old undergoing bilateral symmetric strabismus…

StrabismusJan 5, 2026Read summary
Case ReportOphthalmologyOpen access

Bilateral non-hereditary foveomacular and peripheral retinoschisis in a young female with electrophysiological abnormalities.

A 25-year-old woman with recent left-eye visual diminution had bilateral foveal and peripheral retinoschisis on fundus examination and OCT, with schisis predominantly in the outer plexiform and outer nuclear layers and…

Doc OphthalmolJan 3, 2026Read case
Clinical ResearchOphthalmology

Clinical Outcomes of Index Needle Revision for Failed Deep Sclerectomy in Vietnamese Eyes.

This prospective study assessed first-time needle revision augmented with subconjunctival 5-fluorouracil (5-FU) for failed non-penetrating deep sclerectomy (NPDS) in Vietnamese patients.

Clin TerJan 1, 2026Read summary
Clinical ResearchOphthalmology

Six-Month Outcomes of Ahmed Glaucoma Valve Implantation Using a Patch Graft-Free Scleral Tunnel Technique in Eyes with Refractory Glaucoma: A prospective, non-comparative interventional study.

This prospective, non-comparative interventional case series assessed six-month outcomes of Ahmed FP7 valve implantation using a patch graft-free scleral tunnel technique in 35 eyes of 35 patients with refractory…

Clin TerJan 1, 2026Read summary
Clinical ResearchOphthalmology

Secondary Ophthalmic Artery Chemotherapy for Bilateral Retinoblastoma After Incomplete Response to Intravenous Chemotherapy: Initial Prospective Experience from a Resource-Limited Setting.

This prospective single-centre study assessed short-term outcomes of secondary ophthalmic artery chemotherapy (OAC) in 20 children with bilateral retinoblastoma whose eyes had responded incompletely to intravenous…

Clin TerJan 1, 2026Read summary

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