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359 articles

January 20268

Clinical ResearchCardiology

Impaired endotoxin inactivation, rather than gut translocation, is associated with organ injury in cardiac surgery with cardiopulmonary bypass: An ancilliary analysis of a randomised control trial.

This ancillary analysis of a randomised controlled trial examined endotoxin mass and activity in adults undergoing cardiac surgery with expected cardiopulmonary bypass (CPB) longer than 90 minutes, and assessed…

Eur J AnaesthesiolJan 13, 2026Read summary
Clinical ResearchAnesthesiologyOpen access

Effects of different fractions of inspired oxygen on delayed neurocognitive recovery in patients with one-lung ventilation: a randomized clinical trial.

This randomized clinical trial compared 70% with 100% inspired oxygen during one-lung ventilation in 88 patients aged 30–70 years undergoing thoracoscopic pulmonary lobectomy.

Med Gas ResJan 6, 2026Read summary
Clinical ResearchOrthopedic SurgeryOpen access

Risk prediction models for blood transfusion in patients undergoing total hip and knee arthroplasty: a systematic review and meta-analysis.

This systematic review and meta-analysis evaluated published models predicting perioperative blood transfusion in patients undergoing total hip or knee arthroplasty.

Ann MedJan 5, 2026Read summary
Clinical ResearchAnesthesiologyOpen access

Effects of phenylephrine and norepinephrine with restrictive infusion on oxygenation during one-lung ventilation for lung surgery: a randomized controlled trial.

This randomized controlled trial compared phenylephrine and norepinephrine, each combined with restrictive infusion, against control during thoracoscopic one-lung ventilation in 90 patients undergoing lung surgery.

Ann MedJan 5, 2026Read summary
Case ReportCardiologyOpen access

Intraoperative Discovery of Bioprosthetic Mitral Valve Thrombus on TEE During HeartMate 3 Implantation: Implications for Anesthetic Management and Surgical Planning.

A 73-year-old woman with chemotherapy-induced cardiomyopathy, atrial fibrillation, and a bioprosthetic mitral valve was assessed for LVAD implantation.

Semin Cardiothorac Vasc AnesthJan 5, 2026Read case
Clinical ResearchGeneral SurgeryOpen access

Pain and Analgesic Doses Versus Free Interleukin 18 (IL-18F) Blood Levels Following Surgery: A Prospective Randomized Study of Patients With Minilaparotomy Cholecystectomy Versus Laparoscopic Cholecystectomy.

This prospective randomized study compared patients undergoing laparoscopic or minilaparotomy cholecystectomy, examining perioperative blood levels of IL-18, IL-18 binding protein (IL-18BP), free IL-18 (IL-18F), and…

In VivoJan 1, 2026Read summary
Clinical ResearchAnesthesiology

Dexamethasone Versus Dexmedetomidine as Adjuncts to Serratus Anterior Plane Block for Postoperative Analgesia After Modified Radical Mastectomy: A Randomized Clinical Trial.

This randomized clinical trial compared dexamethasone with dexmedetomidine as an adjunct to serratus anterior plane block in 126 female patients undergoing modified radical mastectomy.

Clin TerJan 1, 2026Read summary
Clinical ResearchAnesthesiology

Comparison of Sevoflurane and Propofol-Fentanyl for Laryngeal Mask Airway Insertion in Pediatric cases.

This prospective, single-blinded randomized study compared sevoflurane with intravenous propofol-fentanyl for laryngeal mask airway (LMA) insertion in 60 children aged 4–12 years with ASA physical status I or II…

Clin TerJan 1, 2026Read summary

December 20256

Clinical ResearchAnesthesiology

Lung Ultrasound Evaluation of the Impact of Inspired Oxygen Fraction on Atelectasis During Induction of General Anesthesia in Pediatric Patients: A Randomized Controlled Trial.

This prospective randomized controlled trial compared 100% with 50% inspired oxygen during induction of general anesthesia in 114 children aged 1–7 years with ASA physical status I–II.

ShockDec 30, 2025Read summary
Clinical ResearchOtolaryngology (ENT)

The Retropharyngeal Internal Carotid Artery: A Systematic Review, Meta-Analysis of the Current Literature, and Evidence Sampling.

This systematic review and meta-analysis assessed the prevalence and imaging features of retropharyngeal internal carotid arteries (RP-ICAs) in adult imaging cohorts.

Clin AnatDec 27, 2025Read summary
Clinical ResearchAnesthesiologyOpen access

Efficacy of esketamine in reducing nausea and vomiting after anesthesia: a systematic review and meta-analysis of randomized controlled trials.

This systematic review and meta-analysis assessed perioperative esketamine for preventing postoperative nausea and vomiting (PONV), drawing on 38 randomized controlled trials involving 3,425 patients.

Ann MedDec 26, 2025Read summary
Clinical ResearchCardiology

Association of Preoperative Frailty and Postoperative Outcomes in Older Adults Undergoing Major Cardiac Procedures: A Systematic Review and Meta-Analysis.

This systematic review and random-effects meta-analysis examined preoperative frailty and postoperative outcomes in older adults undergoing major cardiac procedures.

Anesth AnalgDec 23, 2025Read summary
Clinical ResearchAnesthesiology

A Comparison of the Efficacy and Complications Between Intraosseous and Periarticular Multimodal Analgesic Cocktail Injections After Primary Total Knee Arthroplasty: A Randomized Controlled Trial.

This prospective randomised controlled trial compared intraosseous (IO) with periarticular (PA) multimodal analgesic injections after primary total knee arthroplasty.

J ArthroplastyDec 18, 2025Read summary
Clinical ResearchAnesthesiologyOpen access

Thoracic Ultrasound-Guided Regional Nerve Blockade for Pain Management Following Open Heart Surgery in Children: A Systematic Review and Network Meta-analysis of Analgesic Efficacy and Impact on Postoperative Opioid Requirements.

This systematic review and network meta-analysis compared single-shot ultrasound-guided regional nerve blocks used within multimodal analgesia for children undergoing open cardiac surgery through median sternotomy.

Pediatr CardiolDec 8, 2025Read summary

November 20256

Clinical ResearchAnesthesiology

Comparison of the Effect of Left Head Rotation versus the Direct Epiglottis Lifting Technique on Glottic View during C-MAC Videolaryngoscopy in Patients with Difficult Airway.

This prospective, randomized, double-blinded trial compared left head rotation (LeHeR) with direct epiglottis lifting during C-MAC D-blade videolaryngoscopy in 60 adults with difficult airways.

Ann Afr MedNov 28, 2025Read summary
Clinical ResearchNephrology

Risk factors for postoperative acute kidney injury in major non-cardiac surgery: Systematic review with meta-analysis.

This systematic review and meta-analysis examined preoperative and intraoperative factors associated with acute kidney injury after major non-cardiac surgery. Of 533 studies identified, ten met the inclusion criteria.

J Perioper PractNov 27, 2025Read summary
Clinical ResearchGeneral Surgery

Comparison of Postoperative Pain Following Modified Radical Mastectomy under Thoracic Epidural Anesthesia versus General Anesthesia: A Randomized Control Trial.

This randomized controlled trial compared thoracic epidural anesthesia with general anesthesia using a laryngeal mask airway in 100 patients undergoing unilateral modified radical mastectomy.

Ann Afr MedNov 27, 2025Read summary
Clinical ResearchAnesthesiology

Comparison of inhalational methoxyflurane, intranasal fentanyl, and intravenous morphine for treatment of prehospital acute pain in Norway (PreMeFen): a randomised, non-inferiority, three-arm, phase 3 trial.

PreMeFen was a randomised, open-label, three-arm phase 3 non-inferiority trial in Norwegian ambulance services, comparing inhaled methoxyflurane with intranasal fentanyl and intravenous morphine for acute traumatic or…

LancetNov 20, 2025Read summary
Clinical ResearchAnesthesiologyOpen access

Comparison of Ultrasound-assisted versus Landmark-guided Subarachnoid Block in Patients of Ankylosing Spondylitis Undergoing Total Hip Replacement: A Prospective Randomized Trial.

This prospective randomized trial compared ultrasound-assisted with landmark-guided subarachnoid block in 60 patients with ankylosing spondylitis undergoing elective total hip arthroplasty.

Ann Afr MedNov 20, 2025Read summary
Clinical ResearchAnesthesiology

Comparison of Ease of Awake Intubation Using Traditional Fibreoptic Bronchoscope Versus Hybrid Technique with Videolaryngoscopic Assistance in Patients with Difficult Airway.

This prospective randomized study compared traditional awake fibreoptic intubation with a hybrid fibreoptic technique assisted by a C-MAC videolaryngoscope in 60 patients with difficult airways and a glottic opening…

Ann Afr MedNov 20, 2025Read summary

September 20252

May 20251

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