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406 articles
March 20263
A Systematic Review of Machine Learning Models For Sepsis Prediction: An Appraise-Ai Approach.
This systematic review assessed machine-learning models for sepsis prediction and the quality of the supporting research. It included 53 studies, mainly retrospective cohort studies published from 2020 to 2024, and…
Effects of Moderate-Frequency Resistance Training on Cardiometabolic Risk Factors in Adults With Overweight or Obesity: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed moderate-frequency resistance training (2–3 sessions per week) in nonathletic adults with overweight or obesity.
High-Flow Nasal Oxygen and the Risk of Gastric Insufflation: A Systematic Review and Meta-Analysis Supplemented by Narrative Synthesis.
High-flow nasal oxygen (HFNO) generates positive airway pressure, raising concerns about gastric insufflation and aspiration risk.
February 20266
Changes in hemoglobin levels and cardiometabolic health in adults with metabolic syndrome - a secondary outcome analysis of a six-month randomized controlled trial.
This secondary outcome analysis of a six-month randomized controlled trial examined whether hemoglobin (Hb) changes tracked cardiometabolic changes in 64 adults with metabolic syndrome participating in a…
High-flow oxygen therapy in comparison with low-level pressure support ventilation for spontaneous breathing trials: A two-center, non-inferiority, randomized controlled study.
This two-centre, open-label, non-inferiority randomised controlled trial compared high-flow oxygen therapy (HFOT) with low-level pressure support ventilation (PSV) during 30-minute spontaneous breathing trials (SBTs) in…
Views and Experiences of People With Dementia, Informal Caregivers and Professionals on Eating and Drinking Difficulties: A Qualitative Systematic Review.
This qualitative systematic review examined how people with dementia, informal caregivers and professionals experience eating and drinking difficulties.
Rehabilitation Course Through Compassionate Use of JenaValve Trilogy Heart Valve System in a Patient With Left Ventricular Assist Device: A Case Study.
A 47-year-old man with a destination HeartMate 3 LVAD developed methicillin-susceptible Staphylococcus aureus bacteremia and severe aortic insufficiency, leading to cardiogenic shock.
Sex differences in the clinical and surgical management after intracerebral hemorrhage: A post hoc analysis of the INTERACT3 clinical trial.
This post hoc analysis of the international, stepped-wedge cluster-randomised INTERACT3 trial examined sex differences in acute clinical and surgical care among 7,036 adults with intracerebral hemorrhage; 36% were…
Macrophage Activation Syndrome Associated with Adult-onset Still's Disease Successfully Treated with Plasma Exchange and Canakinumab.
A 20-year-old Japanese woman with adult-onset Still’s disease developed macrophage activation syndrome despite prednisolone and tocilizumab.
January 20268
Prevalence and incidence of post-intensive care syndrome among intensive care unit survivors: a systematic review and meta-analysis.
This systematic review and random-effects meta-analysis examined post-intensive care syndrome (PICS) among intensive care unit survivors, synthesising 34 cross-sectional and cohort studies with 6230 participants.
A Case of Diagnostic Delay: Autoimmune Adrenalitis Mimicking Functional Gastrointestinal Disorder.
A 23-year-old man with previously treated tuberculous meningitis presented with recurrent vomiting, generalized weakness, and altered behavior. He was hypotensive and drowsy, with hyponatremia and hyperkalemia.
Low-Dose Aspirin Continuation During Gastric Endoscopic Submucosal Dissection in Patients With Low Thrombotic Risk: A Randomized Trial.
This randomized trial compared continuing versus discontinuing low-dose aspirin around gastric endoscopic submucosal dissection in patients with gastric mucosal neoplasms and low thrombotic risk.
The Endoscopic Removal of a Gastric Bezoar Made of Sodium Zirconium Cyclosilicate Hydrate.
A 77-year-old woman receiving intensive care for acute adrenal insufficiency developed a 37-mm gastric bezoar after sodium zirconium cyclosilicate hydrate (SZC) was administered through a nasogastric tube.
Risk factors of venous thromboembolism in ICU patients: a systematic review and meta-analysis.
This systematic review and meta-analysis examined factors associated with venous thromboembolism (VTE) among patients admitted to intensive care units. Of 2465 studies identified, 30 were included in pooled analyses.
Comparison of the predictive performance of systemic immune-inflammation index and neutrophil-to-lymphocyte ratio for three-month poor functional outcome in ischemic stroke: a systematic review and meta-analysis.
This systematic review and meta-analysis compared the prognostic performance of the systemic immune-inflammation index (SII) and neutrophil-to-lymphocyte ratio (NLR) for poor functional outcome at three months after…
Methodological insights and correlations of short-term BP variability indices.
This analysis examined how four indices of short-term systolic blood pressure variability relate to one another in 65 hypertensive participants aged ≥40 years with obstructive sleep apnoea, using baseline 24-hour…
Workplace Health promotion and Mediterranean diet: a case series.
In a workplace health-promotion study at a university hospital in Rome, two workers received an integrated pathway involving occupational health assessment and personalized dietary counseling.
December 20255
The effect of acupuncture on 24-hour ambulatory blood pressure and circadian rhythm in patients with essential hypertension: a systematic review and meta-analysis of randomised controlled trials.
This systematic review and meta-analysis assessed acupuncture’s effects on 24-hour ambulatory blood pressure and circadian rhythm in people with essential hypertension.
Association of Preoperative Frailty and Postoperative Outcomes in Older Adults Undergoing Major Cardiac Procedures: A Systematic Review and Meta-Analysis.
This systematic review and random-effects meta-analysis examined preoperative frailty and postoperative outcomes in older adults undergoing major cardiac procedures.
A systematic review and meta-analysis of routine white blood cell concentrations in people with eating disorders.
This systematic review and meta-analysis examined white blood cell (WBC) concentrations and subtypes in people with anorexia nervosa (AN) or bulimia nervosa (BN), compared with healthy controls, and during weight…
Cognitive impairment after cerebral venous thrombosis: A systematic review and meta-analysis.
This systematic review and meta-analysis assessed cognitive impairment after cerebral venous thrombosis (CVT), using studies with at least 6 months of follow-up.
Novel de novo CLCN7 mutation in refractory osteopetrosis-related osteomyelitis: A case report and multidisciplinary therapeutic dilemmas.
A 57-year-old man with ADO-II presented with refractory mandibular osteomyelitis, facial swelling, and trismus. Imaging showed mandibular osteolysis alongside “sandwich vertebrae” and “Erlenmeyer flask” deformities…
November 20252
Orforglipron, an oral small-molecule GLP-1 receptor agonist, for the treatment of obesity in people with type 2 diabetes (ATTAIN-2): a phase 3, double-blind, randomised, multicentre, placebo-controlled trial.
ATTAIN-2 was a 72-week, phase 3, double-blind, randomised, multicentre, placebo-controlled trial of once-daily oral orforglipron added to lifestyle modification in adults with type 2 diabetes and BMI of at least 27…
Diabetes Self-Care among South Asians in Western Countries: A Systematic Review.
This mixed-methods systematic review synthesised qualitative and quantitative evidence on diabetes self-care among South Asians living in Western countries.
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