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1002 articles
August 202624
Exploring the Feasibility of Ultrasound-Guided Supraclavicular Nerve Blocks for Distal Forearm Fracture Management in Pediatric Patients.
Three pediatric patients presented with distal forearm fractures requiring reduction. Due to various factors, including the need to monitor the Glasgow coma scale and parental preferences, ultrasound-guided…
Minor physical anomalies in ASD and ADHD: a systematic review and meta-analysis.
This systematic review and meta-analysis examined minor physical anomalies (MPAs) in individuals with autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) compared to typically developing…
Functional Outcomes of Pediatrics and Adolescent Pelvic Fractures: A Systematic Review.
This Level III systematic review assessed functional and structural outcomes after pelvic fractures in children and adolescents, drawing on 14 retrospective and prospective cohort studies and case series (n=731).
Autism and Self-Esteem: A Systematic Review Quantifying Differences Between Autistic and Non-Autistic Adolescents and Investigating Associations With Mental Health Difficulties.
This systematic review examined self-esteem in autistic adolescents aged 10–19 years, comparing levels with non-autistic peers and assessing associations with mental health symptoms.
Emergent Reversal of Intracranial Hemorrhage Using 4-Factor Prothrombin Complex Concentrate in a Pediatric Patient.
An 11-year-old male with sinusitis complicated by multifocal intracranial abscesses and a superior sagittal sinus thrombus was treated with rivaroxaban.
Dulaglutide vs insulin in adolescents with thalassaemia-induced diabetes: effect on metabolism and atherogenesis (DIADEMA).
The DIADEMA trial compared dulaglutide to insulin in adolescents (10-18 years) with thalassaemia-induced diabetes. After 24 weeks, dulaglutide significantly reduced glycaemic variability (CV decreased from 39.45% to…
Comparative Efficacy, Safety, and Cost of Different Intrapleural Fibrinolytic Agents for the Management of Empyema Thoracis in Children: A Systematic Review.
This systematic review aimed to evaluate the efficacy, safety, and cost of intrapleural fibrinolytic agents for pediatric empyema thoracis.
Identification and characterisation of a novel homozygous KDM5A variant associated with severe axial hypotonia, seizures, and cardiac anomalies.
A patient with severe neurodevelopmental delay had neuromotor delay, profound axial hypotonia with absent head control, mild upper-limb spasticity, a history of seizures, facial dysmorphism and congenital heart disease.
Prevalence and risk factors of nutritional anaemia among adolescents in India: a systematic review with meta-analysis of prevalence.
This systematic review and meta-analysis assessed the prevalence of nutritional anaemia among Indian adolescents aged 10-19 years, analyzing data from 45 studies involving 159,979 participants.
Pediatric Gastric GIST With SDHA Truncation Despite Retained SDHB Staining: A Case Report.
A 14-year-old boy presented with a gastric GIST, which was positive for KIT and DOG1. Genetic analysis revealed a truncating variant in the SDHA gene, indicating SDH deficiency.
Pediatric Mangled Injury.
A pediatric patient sustained a complex upper extremity injury from a motor vehicle accident, involving brachial plexus injury, vascular compromise, bony injury, and denervated muscles.
Effects of attenuated influenza virus administration to young children on pneumococcal density and acquisition in UK families: a randomised controlled trial.
This randomized controlled trial investigated the effects of live attenuated influenza vaccine (LAIV) on pneumococcal density and acquisition in young children and their household contacts in the UK.
Baseline diet quality indicators and 6-month changes in iron and vitamin A biomarkers among rural Ghanaian adolescent schoolgirls: A secondary analysis of the Ten2Twenty-Ghana trial.
This secondary analysis of the Ten2Twenty-Ghana randomized controlled trial examined the relationship between baseline diet quality and changes in iron and vitamin A biomarkers among 300 rural Ghanaian adolescent girls…
Pediatric Postoperative Acute Kidney Injury After Noncardiac Surgery: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated the incidence of postoperative acute kidney injury (AKI) in children undergoing noncardiac surgery, analyzing data from 27 studies with 21,908 patients.
Pineoblastoma in a 5-Year-Old Male: A Case Report and Review of Literature.
A 5-year-old male presented with symptoms indicative of raised intracranial pressure. Imaging studies identified a tumor in the pineal region, which was confirmed as pineoblastoma through histopathological evaluation.
Bridging Resource Gaps in Toxic Epidermal Necrolysis Management: A Case Report Highlighting Innovative Care.
A 2-year-old girl presented with a 6-day history of fever and a rash that progressed to extensive exfoliation of over 70% of her body surface area after starting amoxicillin and clavulanic acid.
Early Ictal Dynamics in Childhood Absence Epilepsy: Scalp EEG Detection of Direct Current Shifts and High-Frequency Oscillations.
Two children with childhood absence epilepsy had typical absence seizures during hyperventilation-provoked scalp EEG. Wide-band recordings captured both direct-current (DC) shifts and high-frequency oscillations (HFOs)…
Three Generations of X-Linked Hypophosphataemia: The Inter-generational Impact of Burosumab Across the Lifespan.
This case report describes three generations of a family affected by X-linked hypophosphataemia (XLH), each receiving burosumab therapy at different life stages.
Systematic Review of the Relationship Between the Presence and Quality of Sidewalks and Children's Physical Health.
This systematic review examined associations between sidewalk availability or quality and physical health outcomes in children.
Does a clinical assessment of upper airway obstruction in robin sequence correspond to sleep study results?
This randomized controlled trial assessed the correlation between clinical evaluations of obstructive sleep apnea (OSA) severity and sleep study results in 29 infants with Robin sequence.
Neurological effects of encapsulated dexamethasone sodium phosphate in children aged 6-9 years with ataxia telangiectasia (NEAT): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial.
The NEAT trial was a multicentre, randomised, double-blind, placebo-controlled phase 3 study assessing the efficacy and safety of encapsulated dexamethasone sodium phosphate (eDSP) in children aged 6-9 years with ataxia…
Shared Decision-Making and the Role of Maternalism in Resolving Difficult End-of-Life Decisions.
We explore the spectrum of shared decision-making, especially the idea of maternalism, which combines patient or surrogate preferences and goals with the clinician's responsibility to provide care within the boundaries…
Molecular stability overrides size in giant pediatric pheochromocytoma.
A 16-year-old female presented with severe hypertension and hyperglycemia, initially misdiagnosed with essential hypertension and type 2 diabetes.
Biallelic SLC20A2 loss-of-function in severe early-onset neurodevelopmental disorder with brain calcification.
A child presented in early infancy with refractory seizures, severe hypotonia, left hemiplegia, profound developmental impairment, bilateral cataracts, and progressive intracranial calcification.
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