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1316 articles
October 202624
Effect of injectable platelet rich fibrin augmented with vitamin c compared to injectable platelet rich fibrin alone on healing of necrotic mature single rooted teeth with chronic periapical periodontitis following regenerative endodontic therapy (a randomized controlled trial).
This randomized controlled trial compared injectable platelet-rich fibrin (i-PRF) with and without vitamin C during regenerative endodontic treatment in 28 healthy patients with necrotic mature single-rooted teeth and…
Menstrual health challenges and associated barriers among tribal adolescent girls in India: A systematic review.
This systematic review synthesised quantitative, qualitative and mixed-methods research on menstrual health among tribal adolescent girls in India.
Immediate Versus Staged Complete Revascularization in Multivessel Disease and STEMI: A Meta-Analysis of Randomized Trials.
This frequentist meta-analysis of four multicentre randomised trials compared immediate with staged complete revascularization in 2,651 patients with STEMI and multivessel disease.
Osteopathic manual therapy in fibromyalgia: a pilot study.
This pilot randomised controlled trial assessed whether adding osteopathic manual therapy to Clinical Pilates improved pain, symptom severity, pressure pain threshold, and sleep in 20 women with fibromyalgia.
Analgesic efficacy of uni-level erector spinae plane block in breast cancer surgery patients: a systematic review and Meta-analysis.
This systematic review and meta-analysis assessed uni-level erector spinae plane block (ESPB) as an adjunct to general anesthesia and opioids for breast cancer surgery.
Occlusion-Focused Triage vs Very-High-Risk NSTEMI Criteria: A DIFOCCULT-3 Substudy.
This substudy of the multicenter, cluster-randomized DIFOCCULT-3 trial compared occlusion/nonocclusion (OMI/NOMI) classification with the conventional STEMI/NSTEMI framework and guideline-defined very-high-risk NSTEMI…
Impact of Extent of Coronary Artery Disease in Transcatheter Aortic Valve Replacement: A PRO-TAVI Substudy.
This post hoc substudy of the multicentre randomised PRO-TAVI trial examined whether coronary disease complexity, measured by SYNTAX score, was associated with outcomes among 466 patients with significant coronary…
Robotic-assisted versus conventional coronary artery bypass grafting: a systematic review, meta-analysis, and trial sequential analysis of 39,918 patients.
This systematic review and meta-analysis compared robotic-assisted with conventional coronary artery bypass grafting (CABG) across nine observational studies involving 39,918 patients.
The effectiveness of guided botulinum toxin "A" injection to the masticatory muscles in the management of condylar and sub condylar fractures: a randomized controlled clinical trial.
This randomized controlled clinical trial compared ultrasound-guided botulinum toxin A injections into the masseter, temporalis and lateral pterygoid muscles plus closed reduction with closed reduction alone in 16…
Predictors of immunological non-response despite virological suppression in people living with HIV on antiretroviral therapy: A systematic review and meta-analysis.
This systematic review and meta-analysis examined clinical, demographic and molecular predictors of inadequate CD4+ T-cell recovery despite viral suppression on antiretroviral therapy in people living with HIV.
Continuous intrathecal therapy for refractory cancer pain: A systematic review and meta-analysis focusing on partially implanted devices.
This systematic review and meta-analysis assessed partially implanted intrathecal devices (PIDs) for adults with refractory cancer-related pain, comparing them with conventional medical management and, in comparative…
Progestogens, cervical cerclage, and cervical pessary for preventing preterm birth in asymptomatic singleton pregnancies with a sonographic short cervix and no previous history of spontaneous preterm birth: systematic review and bayesian network meta-analysis.
This systematic review and Bayesian network meta-analysis compared interventions to prevent preterm birth in asymptomatic women with singleton pregnancies, a sonographic short cervix, and no previous spontaneous preterm…
Improvement in peripheral airway function after a 12-week exercise intervention in COPD.
This prospective, multicenter, single-arm non-randomized intervention study assessed lung function, exercise capacity and symptoms before and after a 12-week supervised exercise program in 62 people with COPD.
Next-generation pharmacological strategies for Parkinson's disease: a systematic literature review of symptom management and disease modification.
This PRISMA 2020 systematic literature review assessed pharmacological and emerging therapeutic strategies for symptom management and disease modification in Parkinson disease.
Comparative efficacy of topical garlic extract and 20% podophyllin solution in the treatment of female genital warts: a triple-blind randomized clinical trial.
This triple-blind randomized clinical trial compared topical 5% garlic extract with 20% podophyllin in 74 women with genital warts, applied weekly for four weeks.
Effectiveness of a fully digital mandibular advancement appliance compared with CPAP in the treatment of obstructive sleep apnea.
This crossover clinical study compared a fully digital mandibular advancement appliance (MAA) with CPAP in 20 adults with obstructive sleep apnea (OSA), confirmed by polysomnography and non-adherent to CPAP.
Effectiveness of a self-management intervention on clinical outcomes among patients with type 2 diabetes at high risk for Diabetic Kidney Disease: A Randomised Controlled Trial.
This prospective, two-arm randomised controlled trial at a tertiary hospital in China evaluated a structured self-management programme in 134 adults with type 2 diabetes classified as at high risk of diabetic kidney…
Sustained potassium control and recurrent hyperkalemia during individualized potassium-guided sodium zirconium cyclosilicate titration in maintenance hemodialysis: a post hoc analysis of a randomized trial.
This exploratory post hoc analysis of a single-centre, open-label randomised trial assessed sustained potassium control with individualized potassium-guided sodium zirconium cyclosilicate (SZC) in 116 maintenance…
Necroptosis as a key player in cervical cancer progression and management: a systematic review and transcriptomic cross-study consensus analysis.
This systematic review and transcriptomic cross-study consensus analysis examined published evidence on necroptosis in cervical cancer, including seven prognostic gene models and exploratory analyses of overlapping…
How Do Mindfulness-Based and Cognitive Behavioral Therapies Help Adults With Opioid-Treated Chronic Low Back Pain? A Qualitative Study.
This qualitative study explored how mindfulness-based therapy (MBT) and cognitive behavioral therapy (CBT) may help adults with chronic low back pain treated with opioids.
Negotiating Care Over Time: A Systematic Review of Alzheimer's Disease Caregiving Through a Life Course Approach.
This systematic review examined sociological research published between 2004 and 2024 on family caregiving for people with Alzheimer’s disease, focusing on how caregiving intersects with caregivers’ life trajectories…
Can't Name It, Can't Log Off: Alexithymia and Problematic Internet-Related Behaviors: A Systematic Review and Meta-Analysis.
This preregistered systematic review and meta-analysis examined quantitative associations between alexithymia and problematic Internet-related behaviors (PIB), including problematic Internet, smartphone, social media…
Inhibin B as a biomarker for ovarian reserve and ovarian response: systematic reviews and meta-analyses of diagnostic test accuracy.
This systematic review and meta-analysis assessed the diagnostic accuracy of inhibin B compared with anti-Müllerian hormone (AMH) for ovarian reserve and ovarian response.
Exercise modality and planned weekly exercise exposure for motor outcomes in Parkinson's disease: a systematic review, Bayesian network meta-analysis, and meta-regression.
This systematic review and Bayesian network meta-analysis synthesized 173 randomized trials of exercise in people with Parkinson’s disease, assessing motor symptoms, balance, walking speed, and Timed Up and Go (TUG).
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