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72 articles
September 20267
Bone metastases in lung carcinoids: current challenges in diagnosis and treatment -A systematic review of an unexplored issue.
This systematic review examined bone metastases (BMs) in lung carcinoid patients, revealing an incidence of 17.2%. The study highlighted the challenges in diagnosis and treatment, noting that BMs were predominantly…
Utility of 99m Tc-FAPI-46 SPECT/CT in Restaging Hepatocellular Carcinoma : A Case Report.
A 54-year-old man with hepatocellular carcinoma developed diffuse bone pain six months after radiofrequency ablation. Restaging with 99mTc-FAPI-46 SPECT/CT showed locally active primary HCC and widespread FAPI-avid bone…
Detected Huge Urinoma With 99mTc-PSMA Activity on Initial Prostate Cancer Staging.
A 62-year-old man with newly diagnosed prostate adenocarcinoma underwent staging with 99mTc-PSMA and 99mTc-MDP scans. The bone scan indicated tracer activity near the left kidney, which was further evaluated with…
Unexpected ¹⁸F-DOPA Uptake in Pediatric Posterior Mediastinal Ewing Sarcoma: A Diagnostic Pitfall in Pediatric Oncology.
A pediatric patient with posterior mediastinal Ewing sarcoma had an unexpected finding on ¹⁸F-DOPA PET/CT: the tumor showed tracer uptake.
Solitary Flat Bone Metastasis of Follicular Thyroid Carcinoma: Complete Molecular and Partial Structural Response After 2 131 I Therapies.
A patient with follicular thyroid carcinoma presented with a solitary metastasis in the right iliac bone, which remained structurally unchanged after two high-dose 131 I therapies.
Functional Renal Assessment via Dynamic LAFOV 18 F-FDG PET/CT in a Patient with Recurrent Extranodal Marginal-Zone Lymphoma.
A 72-year-old man with recurrent extranodal marginal-zone B-cell lymphoma underwent dynamic long-axial-field-of-view 18 F-FDG PET/CT.
Targeting Fibroblast Activation Protein with [177Lu]Lu-FAP-2286 in Patients with Advanced Solid Tumors in the Phase I LuMIERE Trial.
The Phase I LuMIERE trial evaluated the safety of [177Lu]Lu-FAP-2286 in 27 heavily pretreated patients with advanced solid tumors.
August 202611
A Novel Protocol for Pre-Treatment Diagnostic 131 I Scan Within 24 Hours Post-Second rhTSH Administration to Guide Radioiodine Therapy in Differentiated Thyroid Cancer.
This single-center, prospective clinical trial evaluated the feasibility of performing a diagnostic 131 I whole-body scan (Dx-WBS) within 24 hours after the second rhTSH injection in patients with differentiated thyroid…
Two Cases of Solitary Corpus Cavernosum Metastasis From Prostate Cancer Detected by 68 Ga-PSMA PET Imaging.
Two patients with prostate cancer developed rapidly rising PSA after radical prostatectomy, with no prior evidence of metastatic disease.
False-Positive 123I-MIBG Uptake Attributable to Contralateral Erector Spinae Muscle Hypertrophy Following Retroperitoneal Surgery in a Child With Neuroblastoma.
A 5-year-old girl with high-risk neuroblastoma underwent ¹²³I-MIBG SPECT/CT after resection of a right adrenal tumor; baseline imaging showed no abnormal uptake.
Persistent Colonic Activity on 99m Tc-MDP Whole Bone Scintigraphy Revealing a Complex Ureterorectal Fistula.
Intense bowel activity on 99m Tc-MDP bone scintigraphy is often dismissed as urinary contamination or radiopharmaceutical instability, but persistent uptake should prompt an anatomic search.
SSTR Antagonist PET/CT Unveils Occult Hepatic Metastases in Rectal Neuroendocrine Tumor: Superiority Over 68 Ga-DOTANOC and Clinical Upstaging.
68 Gallium NODAGA-JR11, a somatostatin receptor (SSTR) antagonist, exhibits superior sensitivity in detecting hepatic metastases of neuroendocrine tumors compared with the agonist tracer 68 Ga-DOTANOC PET/CT.
Multiple Radioiodine-avid Skin Metastases From Thyroid Carcinoma Detected on Posttherapy 131 I SPECT/CT.
A 77-year-old man with papillary thyroid carcinoma had achieved remission after radioactive iodine treatment for metastatic disease.
Multitarget Molecular Imaging-based Characterization of Gastrointestinal Stromal Tumor.
An incidental gastric gastrointestinal stromal tumor (GIST) was identified and evaluated using three separate PET radiopharmaceuticals.
Metabolic Tumor Volume Is More Accurate Than SUV Metrics in PSMA-PET/CT Analysis Across Different PET/CT Scanners.
A 66-year-old man with metastatic prostate cancer had PSMA-avid local recurrence on follow-up PSMA-PET/CT and MRI. Across three PET studies, SUVmax, SUVmean, and total lesion glycolysis (TLG) did not track consistently…
From static to dynamic SPECT/CT: A systematic review of clinical applications and perspectives.
This systematic review evaluates the clinical applications of dynamic SPECT/CT across various organ systems, particularly in cardiology and nephrology.
Focal Vascular Photopenia as a Metabolic Signature of Pulmonary Embolism on AI-Enhanced 18 F-FDG PET/CT.
Artificial intelligence (AI)-enhanced reconstruction of 18 F-FDG PET/CT may reveal important metabolic patterns barely visible on standard reconstructions.
Discordance of 99mTc-PYP Uptake in the Myocardium and Breast Both Before and After Treatment in Transthyretin Cardiac Amyloidosis.
An 87-year-old man with wild-type transthyretin cardiac amyloidosis (ATTRwt-CM) presented with discordant 99mTc-PYP uptake in the myocardium and breast.
July 20266
Near-complete Response of Bilateral Adrenal Metastases to 177Lu-PSMA Therapy in Castration-resistant Prostate Cancer on Posttherapeutic SPECT-CT Follow Up.
A 72-year-old man with castration-resistant prostate adenocarcinoma underwent 68Ga-PSMA-11 PET/CT for restaging due to significantly increased PSA levels during chemotherapy.
Renal Ewing Sarcoma Mimicking Neuroblastoma: A Multitracer PET/Scintigraphic Imaging Pitfall.
A 6-year-old boy presented with a left suprarenal mass initially suspected to be neuroblastoma. An inconclusive biopsy led to further imaging, where I-131 mIBG scintigraphy showed no uptake, Ga-68 DOTANOC PET/CT…
Pre-therapeutic PSMA PET Imaging Biomarkers Demonstrate Prognostic Value in Patients Undergoing [ 177 Lu]Lu-PSMA Therapy: A Systematic Review and Meta-analysis.
This systematic review and meta-analysis evaluated the prognostic value of pre-therapeutic PSMA PET imaging biomarkers in 2993 patients undergoing [177 Lu]Lu-PSMA therapy for metastatic castration-resistant prostate…
More Prominent 18 F-FDG Uptake Than 68 Ga-FAPI-04 in Nongestational Choriocarcinoma.
A 56-year-old man was found to have nongestational choriocarcinoma of unknown primary with multiple metastases. On PET/CT, the lesions showed intense 18F-FDG uptake but limited accumulation of 68Ga-FAPI-04.
Iodine Avid Muscle Metastases Mimicking Skeletal Lesions on Whole-Body Iodine Scan in Poorly Differentiated Thyroid Carcinoma -SPECT/CT to the Rescue.
A patient with poorly differentiated thyroid carcinoma (PDTC) presented with multifocal muscle metastases that were iodine-avid, leading to confusion with skeletal lesions on whole-body iodine scans.
[ 18 F]FDG PET/MRI for axillary staging in node positive breast cancer patients receiving primary systemic therapy. A prospective single arm trial.
[18F]FDG PET/MRI was evaluated for axillary staging in node-positive breast cancer patients undergoing primary systemic therapy in a prospective single-arm trial.
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