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1316 articles
October 202624
Time-restricted feeding with resistance training is not superior to conventional feeding for body composition and muscle strength: a systematic review and meta-analysis.
This systematic review and meta-analysis examined time-restricted feeding (TRF) versus conventional diets in healthy adults aged 18 or older undertaking resistance training.
Efficacy and safety of intraoperative red blood cell salvage transfusion for spinal deformity surgery: a systematic review and meta-analysis.
This systematic review and meta-analysis pooled 22 observational studies of spinal deformity surgery, including 2,977 patients treated with intraoperative cell salvage (ICS) or without it.
Ketamine and esketamine during breastfeeding: a systematic review of human pharmacokinetic, infant and lactation outcomes.
This systematic review synthesised human evidence on ketamine and esketamine transfer into breast milk, infant exposure and outcomes, and breastfeeding outcomes after postpartum exposure.
Metallic versus plastic stents for the management of biliary obstruction: A GRADE-assessed systematic review and meta-analysis.
This GRADE-assessed systematic review and meta-analysis compared metallic with plastic stents for benign or malignant biliary obstruction, including randomized and observational studies.
Feasibility and perioperative outcomes of Senhance-assisted robotic cholecystectomy: a single-arm meta-analysis.
This single-arm meta-analysis pooled perioperative outcomes from eight studies of Senhance-assisted robotic cholecystectomy, comprising 198 patients.
Efficacy and Safety of Saffron and Ashwagandha for Stress-Related Mental Health Outcomes: A Systematic Review of Randomized Controlled Trials.
This PRISMA-compliant systematic review synthesised randomised controlled trial evidence on saffron and ashwagandha for stress-related mental health outcomes. It included 31 RCTs among 34 eligible studies.
Concurrent biliary atresia and intestinal atresia: a systematic review of clinical characteristics, pathogenesis, management, and outcomes.
This systematic review examined clinical features, management, and outcomes in patients with concurrent biliary atresia (BA) and intestinal atresia (IA), drawing on case reports, case series, and retrospective reviews.
Tofacitinib 20 vs 30 mg in acute severe ulcerative colitis: a double-blind randomized controlled trial.
This double-blind, pilot randomized controlled trial compared tofacitinib 20 mg/day with 30 mg/day, each given alongside intravenous corticosteroids, in adults with acute severe ulcerative colitis.
Effect of Digital Technology-Based Interventions on Core Symptoms and Cognitive Function in Children With Attention-Deficit/Hyperactivity Disorder: Systematic Review and Meta-Analysis.
This systematic review and meta-analysis pooled 37 randomized controlled trials of digital interventions for children with ADHD, covering computer-based interventions, serious video games, exergames, and virtual…
Effects of complementary therapies on physiological and psychological outcomes in chronic obstructive pulmonary disease patients: A systematic review and meta-analysis of randomized controlled trials.
This systematic review and meta-analysis pooled 36 randomized controlled trials involving 3148 people with COPD to assess complementary therapies, including exercise-based and psychological approaches.
Curcumin in ovarian cancer: mechanistic insights and translational potential.
This systematic review assessed curcumin and curcumin nanoformulations in preclinical ovarian cancer models, evaluating 21 studies.
Effects of Sodium Bicarbonate Ringer's Solution versus Lactate Ringer's Solution on Emergence Time in Patients Undergoing Supratentorial Tumor Resection: A Randomized Controlled Trial.
This randomized controlled trial compared intraoperative sodium bicarbonate Ringer’s solution (BRS) with lactated Ringer’s solution (LRS) in patients undergoing elective supratentorial tumor resection.
Feasibility, Acceptability, and Appropriateness of an 8-Week Supervised Aerobic Exercise Intervention for Adults With Epilepsy: Pilot Randomized Controlled Trial.
This Phase IIb pilot randomized controlled trial assessed the feasibility, acceptability, and appropriateness of an 8-week supervised aerobic exercise program for adults with epilepsy aged 18-65 years.
Near point-of-care nucleic acid amplification tests (NPOC-NAATs) using respiratory specimens for detection of pulmonary tuberculosis.
This Cochrane systematic review and meta-analysis assessed near point-of-care nucleic acid amplification testing for pulmonary tuberculosis in adults, adolescents, and children with presumptive disease.
A multicenter randomized phase III trial of weekly cisplatin chemoradiotherapy versus radiotherapy in elderly patients with head and neck squamous cell carcinoma unfit for high-dose cisplatin: JCOG2405 (ELDER-WEEKLY).
JCOG2405 (ELDER-WEEKLY) is a planned multicenter, randomized phase III trial comparing radiotherapy plus weekly cisplatin (40 mg/m2) with radiotherapy alone in patients aged ≥70 years with locally advanced head and neck…
Estimating the Economic Value of Supported Online Parent-Led Cognitive Behavioral Therapy to Prevent Child Anxiety Problems: Economic Evaluation of the MYCATS Cluster Randomized Controlled Trial.
This economic evaluation alongside the MYCATS parallel-group, superiority cluster randomised trial assessed supported online parent-led cognitive behavioural therapy (OSI+TS) plus usual school practice versus usual…
Changes in ectopic lipids, insulin sensitivity, and beta cell function after a low-fat vegan diet in adults with type 2 diabetes: a 16-week single-arm clinical trial.
This 16-week, single-arm clinical trial examined changes in ectopic lipids, insulin sensitivity, advanced glycation end products, and beta-cell function in 25 adults with type 2 diabetes following an ad libitum low-fat…
Comparative effects of inspiratory and expiratory muscle training on diaphragm adaptations and respiratory function in adolescent athletes: a randomized-controlled study.
This randomized controlled study compared inspiratory muscle training (IMT) with expiratory muscle training (EMST) in 26 adolescent female volleyball players.
Multimodal MRI markers of white matter hyperintensities and their impact on cognition in cerebral small vessel disease: a systematic review.
This systematic review examined associations between multimodal MRI markers of white matter hyperintensities (WMH) and cognition in adults with cerebral small vessel disease.
Association Between a Hybrid Video-Guided Multicomponent Exercise Program With Staff Assistance and Free-Living Gait in Older Adults With Knee and Low Back Pain: Secondary Analysis of a Randomized Controlled Trial.
This secondary analysis of a randomized controlled trial examined whether a 12-week hybrid exercise program affected free-living walking in 59 community-dwelling adults aged 65 years or older with mild to moderate knee…
Genotype-informed docosahexaenoic acid dosing based on the FADS Indel to reduce preterm and prolonged gestation: A secondary analysis of the ADORE randomized trial.
This post hoc secondary analysis of the multicentre ADORE randomised trial examined whether FADS Indel genotype modified the association between DHA dose and gestational outcomes.
Astrocytic and Axonal Injury Biomarkers in AQP4 Antibody-Positive NMOSD: Insights From PREVENT and CHAMPION-NMOSD.
This biomarker analysis used samples from the phase 3 PREVENT and CHAMPION-NMOSD trials to assess serum GFAP and NfL in people with AQP4 antibody-positive NMOSD receiving eculizumab or ravulizumab.
The role of physical activity in oral cancer recovery: a systematic review.
This systematic review examined physical activity and recovery-related outcomes among people living with or beyond oral cancer. It included 24 studies spanning randomised trials, pilot trials, and cohort studies.
Age-adjusted shock index vs. reverse shock index multiplied by Glasgow Coma Scale to evaluate mortality in pediatric trauma: a systematic literature review and meta-analysis.
This systematic review and meta-analysis compared the age-adjusted Shock Index (SIPA) with reverse Shock Index multiplied by Glasgow Coma Scale variants (rSIG/rSIM) for predicting outcomes in trauma patients younger…
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