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1064 articles

July 202624

Clinical ResearchGeriatrics

The prevalence and impact of medication-related harm in people living with dementia - a systematic review and meta-analysis.

This systematic review and meta-analysis examined the prevalence and impact of medication-related harm in people living with dementia (PLWD).

Res Social Adm PharmJul 29, 2026Read summary
Clinical ResearchPsychiatry

Primed to feel, not to flare: Early life adversity and psychological sensitivity to interleukin-6 in a randomized trial among middle-aged female breast cancer survivors.

This randomized, placebo-controlled study examined whether early life adversity (ELA) altered inflammatory and psychological responses in 172 female breast cancer survivors.

Brain Behav ImmunJul 29, 2026Read summary
Clinical ResearchPsychiatry

Controlled breathing and heart rate variability biofeedback for substance use-related outcomes: A systematic review and meta-analysis.

This systematic review and meta-analysis assessed controlled-breathing interventions, with or without heart rate variability biofeedback (HRVB), for substance use-related outcomes in people using alcohol, nicotine, and…

AddictionJul 29, 2026Read summary
Clinical ResearchObstetrics & GynecologyOpen access

Cost Effectiveness of Interventions for Perinatal Anxiety and/or Depression: A Systematic Review of Global Evidence.

This systematic review synthesised full economic evaluations of interventions for perinatal anxiety and/or depression. It included 27 studies: 18 trials, eight economic models and one cohort study, with evidence…

Appl Health Econ Health PolicyJul 29, 2026Read summary
Clinical ResearchNephrologyOpen access

Social determinants of health as predictors of latent symptom clusters in patients undergoing maintenance hemodialysis: A secondary analysis of the HOPE consortium randomized trial.

This secondary analysis of baseline data from the HOPE Consortium randomized trial examined symptom clusters and social determinants of health among 643 people receiving maintenance hemodialysis who had chronic pain.

J PainJul 29, 2026Read summary
Clinical ResearchPsychiatry

Internet-based acceptance and commitment therapy (iACT) improves professional psychological help-seeking attitudes: A randomized controlled trial.

This randomized controlled trial evaluated the effectiveness of Internet-based Acceptance and Commitment Therapy (iACT) in improving professional help-seeking attitudes among 91 male participants (Mean Age = 21.09).

J Affect DisordJul 28, 2026Read summary
Clinical ResearchNeurology

Electroencephalographic correlates of sleepiness: A meta-analysis and narrative review.

This meta-analysis and narrative review examined the relationship between EEG power and excessive daytime sleepiness across various conditions.

Sleep MedJul 28, 2026Read summary
Clinical ResearchPsychiatry

Transcranial direct current stimulation enhances offline consolidation of implicit sequential learning in individuals with insomnia.

This randomized controlled trial examined the impact of transcranial direct current stimulation (tDCS) on sleep quality and implicit sequence learning in 42 individuals with insomnia.

J Psychiatr ResJul 28, 2026Read summary
Clinical ResearchPsychiatry

The prevalence of post-traumatic stress disorder in functional / dissociative seizures: A systematic review and meta-analysis.

This systematic review and meta-analysis examined the prevalence of post-traumatic stress disorder (PTSD) in adults with functional/dissociative seizures (FDS).

SeizureJul 28, 2026Read summary
Clinical ResearchPsychiatry

The role of pro-inflammatory cytokine gene polymorphisms in major depressive disorder: a systematic review.

This systematic review evaluated the association between pro-inflammatory cytokine gene polymorphisms, specifically TNF-α and IL-1β, and major depressive disorder (MDD) in adult populations.

Pharmacogenet GenomicsJul 28, 2026Read summary
Clinical ResearchPsychiatry

Effect of atenolol versus ivabradine on heart rate variability in patients of schizophrenia with clozapine-induced tachycardia: a randomized controlled trial.

This randomized controlled trial compared the effects of atenolol and ivabradine on heart rate variability (HRV) in patients with treatment-resistant schizophrenia experiencing clozapine-induced tachycardia.

Psychiatry ResJul 28, 2026Read summary
Clinical ResearchPsychiatry

Driven toward care, avoiding the end: A systematic review and meta-analysis of the relationship between death anxiety and healthcare utilisation.

This systematic review and meta-analysis examined the relationship between death anxiety and healthcare utilization across 21,271 individuals.

Soc Sci MedJul 28, 2026Read summary
Clinical ResearchPsychiatryOpen access

Comparative Bioavailability of Trimodal (CTx-1301) Versus Bimodal Dexmethylphenidate Modified-Release Formulations in Adults with Attention-Deficit/Hyperactivity Disorder: A Randomized, Single-Dose, Crossover Study.

This randomized, single-dose, crossover study evaluated the pharmacokinetics of trimodal CTx-1301 versus bimodal dexmethylphenidate (d-MPH XR) in adults with ADHD.

CNS DrugsJul 28, 2026Read summary
Clinical ResearchPsychiatry

Omega-3 fatty acids, specialized pro-resolving mediators, and depression: A mechanistic meta-analysis of precursors and clinical implications.

This random-effects meta-analysis examined whether omega-3 polyunsaturated fatty acid supplementation increases circulating precursors of specialized pro-resolving mediators in humans.

Brain Behav ImmunJul 28, 2026Read summary
Clinical ResearchGeneral Surgery

Socioeconomic and geographic variation in response to trauma medical home intervention.

This post hoc retrospective analysis of a multicenter randomized trial examined whether response to a trauma medical home (TMH) differed by rurality and area deprivation among adults aged 50 years or older with…

J Trauma Acute Care SurgJul 28, 2026Read summary
Clinical ResearchPsychiatry

Progressing the evaluation of managing emotions groups in severe mental illness: feasibility of methodology for an effectiveness randomised controlled trial of scaled up delivery.

This feasibility randomized controlled trial evaluated a protocolized group emotion regulation intervention for individuals with severe mental illness, delivered online by junior facilitators.

J Behav Ther Exp PsychiatryJul 27, 2026Read summary
Clinical ResearchPsychiatry

Genetic and environmental origins of the co-occurrence of autistic traits, anxiety and depression: Evidence from meta-analysis and twin study.

This study investigated the genetic and environmental origins of the co-occurrence of autistic traits, anxiety, and depression through a meta-analysis and a twin study.

J Affect DisordJul 27, 2026Read summary
Clinical ResearchPsychiatryOpen access

Examining executive functioning: A randomized controlled trial of alcohol misuse interventions for college students with attention-deficit/hyperactivity disorder.

This randomized controlled trial examined the effectiveness of a brief motivational intervention combined with behavioral activation (BMI + BA) versus BMI with supportive counseling in reducing alcohol misuse among 112…

Psychol Addict BehavJul 27, 2026Read summary
Clinical ResearchPsychiatryOpen access

Acceptance and commitment therapy for moral injury (ACT-MI) and present-centered therapy for moral injury (PCT-MI): Results from a randomized controlled pilot trial with war zone deployed veterans.

This randomized controlled pilot trial evaluated Acceptance and Commitment Therapy for Moral Injury (ACT-MI) and Present-Centered Therapy for Moral Injury (PCT-MI) among 74 war zone-deployed veterans.

Psychotherapy (Chic)Jul 27, 2026Read summary
Clinical ResearchPsychiatry

Heart rate variability and anxiety severity: A systematic review and meta-analysis.

This systematic review and meta-analysis examined the relationship between heart rate variability (HRV) and anxiety severity in adult populations using validated anxiety scales.

Compr PsychiatryJul 27, 2026Read summary
Clinical ResearchPsychiatry

Efficacy of smartphone- and bibliotherapy-delivered multicomponent lifestyle medicine interventions for probable depression: A three-arm randomized controlled trial.

This randomized controlled trial evaluated the efficacy of smartphone- and bibliotherapy-delivered lifestyle medicine interventions in 122 adults with probable depression.

J Affect DisordJul 26, 2026Read summary
Clinical ResearchPsychiatry

Efficacy and Safety Outcomes of Different Plasma Clozapine and Norclozapine Levels in Schizophrenia Spectrum Disorder: A Dose-Response Meta-Analysis Exploring "critical" Levels.

This dose-response meta-analysis examined the relationship between plasma clozapine and norclozapine levels and efficacy and safety outcomes in schizophrenia spectrum disorder, analyzing data from 34 studies with…

Psychiatry ResJul 26, 2026Read summary
Clinical ResearchPsychiatry

Pacing in posttraumatic stress disorder therapy: A meta-regression of treatment frequency and completion rates.

This meta-analysis examined the relationship between treatment frequency and completion rates in PTSD therapies, specifically cognitive processing therapy (CPT), prolonged exposure (PE), and eye movement desensitization…

J Trauma StressJul 26, 2026Read summary
Clinical ResearchPediatrics

Longitudinal MRI studies of children with attention-deficit/hyperactivity disorder: A systematic review.

This systematic review examined longitudinal MRI studies of brain development in children with ADHD, covering 32 studies selected from 3385 screened papers and participants aged 4–18 years at baseline.

Psychiatry Clin NeurosciJul 26, 2026Read summary

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