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1002 articles

July 202624

Clinical ResearchPulmonology

Effectiveness of short-acting beta-2 agonists delivered by metered-dose inhaler with spacer versus nebulizer in acute asthma exacerbations: a systematic review and meta-analysis.

This systematic review and meta-analysis compared short-acting beta-2 agonists delivered by metered-dose inhaler (MDI) with spacer versus nebulizer for acute asthma exacerbations.

J AsthmaJul 13, 2026Read summary
Clinical ResearchPediatrics

Safety and Efficacy of a Novel Aerosolized Surfactant (APC-0101) for the Treatment of Respiratory Distress Syndrome in Preterm Infants: A Randomized Phase 2b Study.

This multicenter, randomized phase 2b trial evaluated two doses of aerosolized surfactant (APC-0101) in 261 preterm infants born at 26–31 weeks’ gestation with early respiratory distress syndrome receiving noninvasive…

J PediatrJul 13, 2026Read summary
Clinical ResearchPediatrics

Effect of Extended Infusion Versus Intermittent Bolus Feedings on Hospital Weight Gain in Extremely Low Birth Weight Infants Born at <29 Weeks of Gestation: A Randomized Noninferiority Clinical Trial.

This randomized noninferiority trial compared extended milk-infusion feeding with every-2-hour intermittent bolus feeding in extremely low birth weight infants born before 29 weeks’ gestation who were starting enteral…

J PediatrJul 13, 2026Read summary
Clinical ResearchPediatrics

Microbial Interactions with Protein Intake and Preterm Infant Body Composition: Secondary Analysis of a Randomized Trial.

This secondary analysis of a randomized controlled trial examined the impact of additional enteral protein supplementation on gut microbiota and body composition in preterm infants (25-28 weeks gestation).

J NutrJul 12, 2026Read summary
Clinical ResearchOtolaryngology (ENT)

"Impact of adenotonsillectomy or adenoidectomy on dentofacial development of children with obstructed sleep disordered breathing - Systematic review".

This systematic review evaluated the impact of adenotonsillectomy and adenoidectomy on dentofacial development in children with obstructed sleep-disordered breathing.

Int J Pediatr OtorhinolaryngolJul 11, 2026Read summary
Clinical ResearchRheumatology

Diagnosis, treatment and monitoring of pediatric Behçet's disease: Systematic literature review informing the ISSAID/PRES recommendations.

This systematic review analyzed 52 studies involving 2929 pediatric patients with Behçet's disease (BD), highlighting its distinct clinical features and treatment variability.

Autoimmun RevJul 11, 2026Read summary
Clinical ResearchPediatrics

Prevalence of plasma coagulation deficiencies and antiphospholipid antibodies positivity in the pediatric population of the Małopolska region: A single-center study from a pediatric hospital in Kraków.

This single-center study assessed the prevalence of plasma coagulation disorders and antiphospholipid antibodies in 120 children aged 3-10 years in the Małopolska region.

Pediatr Hematol OncolJul 10, 2026Read summary
Clinical ResearchPediatrics

Prenatal exposure to indoor PM 2.5 and children's cognitive performance at 4 years of age: an observational analysis from the UGAAR randomized controlled trial.

This observational analysis from the Ulaanbaatar Gestation and Air Pollution Research (UGAAR) randomized controlled trial examined the impact of indoor PM 2.5 exposure during pregnancy on children's cognitive…

Environ PollutJul 10, 2026Read summary
Clinical ResearchPediatrics

Short-term exposure to urban air pollution and asthma-related morbidity in children under five: a PRISMA-guided systematic review with narrative synthesis (2021-2025).

This systematic review examined the impact of short-term urban air pollution exposure on asthma-related morbidity in children under five.

Expert Rev Respir MedJul 10, 2026Read summary
Clinical ResearchPediatrics

Anxiety and depression associated oral health problems in pediatric populations: A systematic review and meta-analysis.

This systematic review and meta-analysis examined the association between anxiety, depression, and oral health problems (OHPs) in pediatric populations.

J Affect DisordJul 9, 2026Read summary
Case ReportCardiology

Hammock mitral valve in a 12-day-old female: pathophysiology, management and legal issues.

A 12-day-old female infant presented with acute heart failure due to undiagnosed hammock mitral valve (HMV), a rare congenital anomaly.

Leg Med (Tokyo)Jul 9, 2026Read case
Clinical ResearchEndocrinology

Prevalence and types of insulin-pump-related skin complications in children and adolescents with type 1 diabetes: A systematic review and meta-analysis.

This systematic review and meta-analysis examined the prevalence and types of insulin-pump-related skin complications in children and adolescents with type 1 diabetes.

Diabetes Res Clin PractJul 9, 2026Read summary
Clinical ResearchPsychiatry

Diet, Sleep, and Physical Activity in Children and Adolescents With Depression: An Umbrella Review of Systematic Reviews.

This umbrella review synthesized evidence from 49 systematic reviews involving 1.9 million participants under 19 years to evaluate the impact of diet, sleep, and physical activity on depression in children and…

J Adolesc HealthJul 9, 2026Read summary
Clinical ResearchPediatricsOpen access

Microbial Etiology of Empyema Thoracis in Children: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis examined the microbial etiology of empyema in children, analyzing 36 studies. It found that Staphylococcus aureus was the most prevalent organism in pleural fluid (38.99%) and…

Indian PediatrJul 9, 2026Read summary
Clinical ResearchPediatrics

Exploring the mechanism of Zhichuanling oral liquid in treating childhood bronchial asthma based on network pharmacology and experimental verification.

This randomized controlled study assessed Zhichuanling Oral Liquid (ZCL) added to conventional treatment in 60 children with bronchial asthma, alongside network pharmacology and mouse and cell experiments.

J AsthmaJul 9, 2026Read summary
Clinical ResearchNeurology

Responsive neurostimulation in pediatric drug-resistant epilepsy: A systematic review and meta-analysis of seizure and non-seizure outcomes, safety, and predictors of response.

This systematic review and meta-analysis evaluated the efficacy and safety of responsive neurostimulation (RNS) in 413 pediatric patients with drug-resistant epilepsy.

SeizureJul 8, 2026Read summary
Case ReportMedical Genetics

From Self-Mutilation to Genetic Diagnosis: A Case Report of Hereditary Sensory and Autonomic Neuropathy Type VIII Illuminating the Role of a Rare PRDM12 Mutation.

A 10-month-old female presented with Hereditary Sensory and Autonomic Neuropathy Type VIII, characterized by congenital insensitivity to pain, self-mutilation, and autonomic dysfunction.

Pediatr NeurolJul 8, 2026Read case
Case ReportNephrologyOpen access

Early-onset lipoprotein glomerulopathy in a 23-month-old boy with homozygous APOE Kyoto variant.

A 23-month-old boy presented with nephrotic syndrome and severe anaemia. A family history of kidney disease, parental consanguinity and enlarged echogenic kidneys on ultrasound prompted early renal biopsy, which showed…

Pediatr NephrolJul 8, 2026Read case
Case ReportPediatricsOpen access

Subcostal single-port robot-assisted resection of a posterior mediastinal tumor in an infant.

A 6-month-old female infant weighing 5.46 kg underwent resection of a 7.0-cm cystic posterior mediastinal tumor. Surgeons used a subcostal approach with the da Vinci Single Port system, creating a 3.5-cm incision and…

Gen Thorac Cardiovasc SurgJul 8, 2026Read case
Clinical ResearchPsychiatryOpen access

Assessment of functional impairment related to post-traumatic stress in children and adolescents: a systematic review.

This systematic review evaluated 15 instruments for assessing post-traumatic stress symptoms (PTSS) and related functional impairment in children and adolescents.

Eur J PsychotraumatolJul 7, 2026Read summary
Clinical ResearchPediatrics

Pediatric triage education for nursing students: Examining the effectiveness of multimedia training.

This randomized controlled trial evaluated the effectiveness of multimedia training on pediatric triage education among 80 nursing students in western Iran.

Int Emerg NursJul 7, 2026Read summary
Clinical ResearchDermatology

Dupilumab treatment improves linear growth and bone biomarkers in children with atopic dermatitis: Post hoc analysis of a phase 3 randomized, placebo-controlled clinical trial and an open-label extension study.

This post hoc analysis of a phase 3 randomized, placebo-controlled trial and its open-label extension examined height and bone alkaline phosphatase (BALP) in children aged 6 to 11 years with severe atopic dermatitis.

J Am Acad DermatolJul 7, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Determination of the effect of simulation-based and booklet-based training on breastfeeding self-efficacy and breastfeeding problems: a randomized controlled study.

This randomized controlled trial evaluated the impact of simulation-based and booklet-based training on breastfeeding self-efficacy and breastfeeding problems among women receiving antenatal care.

NutritionJul 6, 2026Read summary
Clinical ResearchPediatrics

Effect of fortified bovine colostrum on linear growth of children aged 9 to 36 mo: a community-based 3-arm randomized controlled trial in urban slums of Belagavi city, India.

This randomized controlled trial evaluated the impact of fortified bovine colostrum (FBC) on the linear growth of children aged 9 to 36 months in urban slums of Belagavi, India.

Am J Clin NutrJul 6, 2026Read summary

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